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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P52333
Original Database ID gi 508731
Organism Homo sapiens
Annotation tyrosine-protein kinase jak3 (ec
2.7.1.112) (janus kinase 3) (jak-3)de
(leukoc yte janus kinase) (l-jak)
Sequence Length 1124
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs916019 F45 FS   X
rs3212723 P132 PT   H X
5 SNPs found but only 2 displayed. (SNPs in modeled regions)
 

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1isncrystal structure of merlin ferm domain ; PFAM: PF00373 PF00769 ; SCOP: 71400 71401 71402
DBALI1isnA 
CATH3.10.20.90 Domain: 1isnA01 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 (87%)
CATH1.20.80.10 Domain: 1isnA02 Acyl-CoA Binding Protein (100%)
CATH2.30.29.30 Domain: 1isnA03 Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) (100%)
JenaImageLibrary1isn 
Target Sequence
UniProtKBP52333Tyrosine-protein kinase JAK3 (EC 2.7.1.112) (Janus kinase 3) (JAK-3)DE (Leukocyte janus kinase) (L-JAK)
InterProP52333 
PFAMP52333 
ProdomP52333 
GenPept76000248Sequence 199 from patent US 6936450
GenPept508731JAK family protein tyrosine kinase
GenPept4557681 Janus kinase 3; L-JAK [Homo sapiens]
GenPept331498439Sequence 9 from patent US 7902348
GenPept223630057Sequence 9 from patent US 7488808
GenPept21507217Sequence 1 from patent US 6372898
GenPept1708581JAK3_HUMAN TYROSINE-PROTEIN KINASE JAK3 (JANUS KINASE 3) (JAK-3) (LEUKOCYTE JANUS KINASE) (L-JAK)
GenPept155076324Sequence 37 from patent US 7202033
GenPept112061068Sequence 9 from patent US 7070972
GenPept1082565A55747 L-JAK protein-tyrosine kinase - human
GenBankAAA19626.1 JAK family protein tyrosine kinase [Homo sapiens]
UCSCGenomeBrowserP52333