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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link 15559784
Original Database ID gi 31543838
Organism Homo sapiens, synthetic construct
Annotation tyrosine kinase 2
Sequence Length 1187
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs1140386 Q1017 QH  
5 SNPs found but only 1 displayed. (SNPs in modeled regions)
 

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Cross-references

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Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3e64fragment based discovery of jak-2 inhibitors
DBALI3e64A 
CATH3.30.200.20 Domain: 3e64A01 Phosphorylase Kinase; domain 1 (99%)
CATH1.10.510.10 Domain: 3e64A02 Transferase(Phosphotransferase) domain 1 (95%)
JenaImageLibrary3e64 
Target Sequence
UniProtKBQ96CH0Hypothetical protein
InterProQ96CH0 
PFAMQ96CH0 
ProdomQ96CH0 
UniProtKBP29597Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.1.112)
InterProP29597 
PFAMP29597 
ProdomP29597 
RefSeqNP_003322.2 tyrosine kinase 2 [Homo sapiens]
GenPept123984545tyrosine kinase 2
GenPept61363602tyrosine kinase 2
GenPept31543838 tyrosine kinase 2 [Homo sapiens]
GenPept307685239tyrosine kinase 2, partial
GenPept15559784Tyrosine kinase 2
GenPept123998559tyrosine kinase 2, partial
GenBankAAX42416.1 tyrosine kinase 2 [synthetic construct]
GenBankABM83618.1 tyrosine kinase 2 [synthetic construct]
GenBankABM86881.1 tyrosine kinase 2 [synthetic construct]
GenBankAAH14243.1 Tyrosine kinase 2 [Homo sapiens]