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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link 181395
Original Database ID GI 29697562
Organism Homo sapiens
Annotation cytosolic epoxide hydrolase
Sequence Length 554
 

SNP Information

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ResidueAA-Residue
Variants
InterfaceLigandStabilityValidated
rs17057255 R103 RC   X
rs751141 R286 RQ   X
rs4149251 S406 SI  
4 SNPs found but only 3 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
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Cross-references

Show obsolete/secondary identifiers
Mutation Data
PharmGKB   PharmGKB data available for EPHX2
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3i28crystal structure of soluble epoxide hydrolase
DBALI3i28A 
CATH3.40.50.1000 Domain: 3i28A01 Rossmann fold (100%)
CATH1.10.150.240 Domain: 3i28A02 Putative phosphatase; domain 2 (100%)
CATH3.40.50.1820 Domain: 3i28A03 Rossmann fold (100%)
JenaImageLibrary3i28 
Target Sequence
SFLD407104653Structure Function Linkage Database entry: Member of the Haloacid dehalogenase superfamily.
UniProtKBP34913Soluble epoxide hydrolase (SEH) (EC 3.3.2.3) (Epoxide hydratase)DE (Cytosolic epoxide hydrolase) (CEH)
InterProP34913 
PFAMP34913 
ProdomP34913 
GenPept997591Sequence 2 from patent US 5445956
GenPept462369HYES_HUMAN SOLUBLE EPOXIDE HYDROLASE (SEH) (EPOXIDE HYDRATASE) (CYTOSOLIC EPOXIDE HYDROLASE) (CEH)
GenPept4503585 epoxide hydrolase 2, cytoplasmic [Homo sapiens]
GenPept422818S35587 epoxide hydrolase - human
GenPept407104653Sequence 1 from patent US 8263651
GenPept402628289Sequence 1 from patent US 8242170
GenPept29697562Sequence 7 from patent US 6495737
GenPept181395cytosolic epoxide hydrolase
GenBankAAA02756.1 cytosolic epoxide hydrolase [Homo sapiens]
UCSCGenomeBrowserP34913