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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P24941.2
Original Database ID 2A4L_1 Chain A
Organism Cercocebus atys, Cercocebus torquatus atys, etc.
Annotation cdk2_human recname: full=cell
division protein kinase 2; altname:
full=p33 prote in kinase
Sequence Length 298
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs3087335 Y15 YS   X
rs11554376 V18 VL   *
rs2069413 T290 TS   X

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB6q49
DBALI6q49A 
JenaImageLibrary6q49 
Target Sequence
UniProtKBA0A024RB77SubName: Full=Cyclin-dependent kinase 2, isoform CRA_b;
InterProA0A024RB77 
PFAMA0A024RB77 
ProdomA0A024RB77 
UniProtKBH2Q670SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|EMBL:JAA03488.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000008631};
InterProH2Q670 
PFAMH2Q670 
ProdomH2Q670 
UniProtKBG7PIG0SubName: Full=Cell division protein kinase 2 {ECO:0000313|EMBL:EHH66383.1};
InterProG7PIG0 
PFAMG7PIG0 
ProdomG7PIG0 
UniProtKBA8K7C6RecName: Full=Cyclin-dependent kinase 2;EC=2.7.11.22;AltName: Full=Cell division protein kinase 2;AltName: Full=p33 protein kinase;
InterProA8K7C6 
PFAMA8K7C6 
ProdomA8K7C6 
UniProtKBH2NHM8SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000005283};
InterProH2NHM8 
PFAMH2NHM8 
ProdomH2NHM8 
UniProtKBG7N7A7SubName: Full=Cell division protein kinase 2;SubName: Full=Cyclin-dependent kinase 2 isoform 1 {ECO:0000313|EMBL:AFE64714.1};
InterProG7N7A7 
PFAMG7N7A7 
ProdomG7N7A7 
UniProtKBA0A0D9QZ04SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000001593};
InterProA0A0D9QZ04 
PFAMA0A0D9QZ04 
ProdomA0A0D9QZ04 
UniProtKBG3QIR0SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000002276};
InterProG3QIR0 
PFAMG3QIR0 
ProdomG3QIR0 
UniProtKBP24941RecName: Full=Cyclin-dependent kinase 2;EC=2.7.11.22;AltName: Full=Cell division protein kinase 2;AltName: Full=p33 protein kinase;
InterProP24941 
PFAMP24941 
ProdomP24941 
UniProtKBO75100RecName: Full=Cyclin-dependent kinase 2;EC=2.7.11.22;AltName: Full=Cell division protein kinase 2;AltName: Full=p33 protein kinase;
InterProO75100 
PFAMO75100 
ProdomO75100 
UniProtKBA0A096MYH8SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPANP00000004995};
InterProA0A096MYH8 
PFAMA0A096MYH8 
ProdomA0A096MYH8 
UniProtKBA0A8D2F5K7SubName: Full=Cyclin dependent kinase 2 {ECO:0000313|Ensembl:ENSTGEP00000015525}
InterProA0A8D2F5K7 
PFAMA0A8D2F5K7 
ProdomA0A8D2F5K7 
UniProtKBA0A6D2WHB3SubName: Full=CDK2 isoform 1 {ECO:0000313|EMBL:PNI90081.1}
InterProA0A6D2WHB3 
PFAMA0A6D2WHB3 
ProdomA0A6D2WHB3 
UniProtKBH2NHM8SubName: Full=Uncharacterized protein;
InterProH2NHM8 
PFAMH2NHM8 
ProdomH2NHM8 
UniProtKBA0A2K5XCR8Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5XCR8 
PFAMA0A2K5XCR8 
ProdomA0A2K5XCR8 
UniProtKBH2Q670SubName: Full=Uncharacterized protein;
InterProH2Q670 
PFAMH2Q670 
ProdomH2Q670 
UniProtKBA0A6D2W5S7SubName: Full=CDK2 isoform 1 {ECO:0000313|EMBL:PNJ44889.1}
InterProA0A6D2W5S7 
PFAMA0A6D2W5S7 
ProdomA0A6D2W5S7 
UniProtKBA0A2R9B4E4Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2R9B4E4 
PFAMA0A2R9B4E4 
ProdomA0A2R9B4E4 
UniProtKBA0A8J8XG04SubName: Full=Cell division protein kinase 2 {ECO:0000313|EMBL:EHH20842.1}
InterProA0A8J8XG04 
PFAMA0A8J8XG04 
ProdomA0A8J8XG04 
UniProtKBA0A2K6P9I2Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K6P9I2 
PFAMA0A2K6P9I2 
ProdomA0A2K6P9I2 
UniProtKBA0A2J8Q1C4SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|EMBL:JAA03488.1, ECO:0000313|Ensembl:ENSPTRP00000008631}
InterProA0A2J8Q1C4 
PFAMA0A2J8Q1C4 
ProdomA0A2J8Q1C4 
UniProtKBG7N7A7SubName: Full=Cell division protein kinase 2;SubName: Full=Cyclin-dependent kinase 2 isoform 1;
InterProG7N7A7 
PFAMG7N7A7 
ProdomG7N7A7 
UniProtKBG3QIR0SubName: Full=Uncharacterized protein;
InterProG3QIR0 
PFAMG3QIR0 
ProdomG3QIR0 
UniProtKBH9EQQ5SubName: Full=Cell division protein kinase 2 {ECO:0000313|EMBL:EHH20842.1}
InterProH9EQQ5 
PFAMH9EQQ5 
ProdomH9EQQ5 
UniProtKBA0A2J8UHZ4SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000005283}
InterProA0A2J8UHZ4 
PFAMA0A2J8UHZ4 
ProdomA0A2J8UHZ4 
UniProtKBA8K7C6SubName: Full=cDNA FLJ76907, highly similar to Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 1, mRNA;SubName: Full=Cyclin-dependent kinase 2, isoform CRA_b;
InterProA8K7C6 
PFAMA8K7C6 
ProdomA8K7C6 
UniProtKBA0A2K5NT27Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5NT27 
PFAMA0A2K5NT27 
ProdomA0A2K5NT27 
UniProtKBA0A2K5VPV1SubName: Full=Cell division protein kinase 2 {ECO:0000313|EMBL:EHH66383.1}
InterProA0A2K5VPV1 
PFAMA0A2K5VPV1 
ProdomA0A2K5VPV1 
UniProtKBA0A2K5IHJ1Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5IHJ1 
PFAMA0A2K5IHJ1 
ProdomA0A2K5IHJ1 
UniProtKBA0A2K6E4W9Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K6E4W9 
PFAMA0A2K6E4W9 
ProdomA0A2K6E4W9 
UniProtKBA0A2K6MMD4Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K6MMD4 
PFAMA0A2K6MMD4 
ProdomA0A2K6MMD4 
UniProtKBG7PIG0SubName: Full=Cell division protein kinase 2;
InterProG7PIG0 
PFAMG7PIG0 
ProdomG7PIG0 
UniProtKBP24941.2CDK2_HUMAN RecName: Full=Cell division protein kinase 2; AltName: Full=p33 protein kinase
InterProP24941.2 
PFAMP24941.2 
ProdomP24941.2 
UniProtKBP24941RecName: Full=Cyclin-dependent kinase 2;EC=2.7.11.22;AltName: Full=Cell division protein kinase 2;AltName: Full=p33 protein kinase;
InterProP24941 
PFAMP24941 
ProdomP24941 
UniProtKBO75100RecName: Full=Cyclin-dependent kinase 2;EC=2.7.11.22;AltName: Full=Cell division protein kinase 2;AltName: Full=p33 protein kinase;
InterProO75100 
PFAMO75100 
ProdomO75100 
UniProtKBA8K7C6RecName: Full=Cyclin-dependent kinase 2;EC=2.7.11.22;AltName: Full=Cell division protein kinase 2;AltName: Full=p33 protein kinase;
InterProA8K7C6 
PFAMA8K7C6 
ProdomA8K7C6 
RefSeqXP_023066604.1cyclin-dependent kinase 2
RefSeqXP_008593099.1PREDICTED: cyclin-dependent kinase 2 isoform X2
RefSeqXP_025256626.1cyclin-dependent kinase 2 isoform X2
RefSeqXP_030678342.1cyclin-dependent kinase 2
RefSeqXP_522432.2 PREDICTED: cyclin-dependent kinase 2 [Pan troglodytes]
RefSeqXP_032029332.1cyclin-dependent kinase 2
RefSeqNP_001789.2 cell division protein kinase 2 isoform 1 [Homo sapiens]
RefSeqXP_033077640.1cyclin-dependent kinase 2
RefSeqXP_002823433.1 PREDICTED: cell division protein kinase 2-like isoform 1 [Pongo abelii]
1717387A1717387A cyclin A dependent p33 kinase:SUBUNIT=2
PDB1F5QCChain C, Crystal Structure Of Murine Gamma Herpesvirus Cyclin Complexed To Human Cyclin Dependent Kinase 2
PDB1DM2AChain A, Human Cyclin-Dependent Kinase 2 Complexed With The Inhibitor Hymenialdisine
PDB1DM2A Chain A, Human Cyclin-Dependent Kinase 2 Complexed With The Inhibitor Hymenialdisine
PDB1FVVC Chain C, The Structure Of Cdk2CYCLIN A IN COMPLEX WITH AN OXINDOLE Inhibitor
PDB1DI8AChain A, The Structure Of Cyclin-Dependent Kinase 2 (Cdk2) In Complex With 4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline
PDB1FVTAChain A, The Structure Of Cyclin-Dependent Kinase 2 (Cdk2) In Complex With An Oxindole Inhibitor
PDB1FVTA Chain A, The Structure Of Cyclin-Dependent Kinase 2 (Cdk2) In Complex With An Oxindole Inhibitor
PDB1DI8A Chain A, The Structure Of Cyclin-Dependent Kinase 2 (Cdk2) In Complex With 4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline
PDB1E1XA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor Nu6027
PDB1E1XAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor Nu6027
PDB1FINCChain C, Cyclin A-Cyclin-Dependent Kinase 2 Complex
PDB1F5QC Chain C, Crystal Structure Of Murine Gamma Herpesvirus Cyclin Complexed To Human Cyclin Dependent Kinase 2
PDB1FINAChain A, Cyclin A-Cyclin-Dependent Kinase 2 Complex
PDB1F5QAChain A, Crystal Structure Of Murine Gamma Herpesvirus Cyclin Complexed To Human Cyclin Dependent Kinase 2
PDB1FINC Chain C, Cyclin A-Cyclin-Dependent Kinase 2 Complex
PDB1E1VAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor Nu2058
PDB1E1VA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor Nu2058
PDB1R78AChain A, Cdk2 Complex With A 4-alkynyl Oxindole Inhibitor
PDB1R78A Chain A, Cdk2 Complex With A 4-Alkynyl Oxindole Inhibitor
PDB1PXPAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor N-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]- N',N'-Dimethyl-Benzene-1,4-Diamine
PDB1PXNAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)- Pyrimidin-2-Ylamino]-Phenol
PDB1PXMA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2- Ylamino]-Phenol
PDB1PXJAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine
PDB1PXIA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2- Ylamine
PDB1P2AAChain A, The Structure Of Cyclin Dependent Kinase 2 (Ckd2) With A Trisubstituted Naphthostyril Inhibitor
PDB1OL2AChain A, Cyclin A Binding Groove Inhibitor H-Arg-Arg-Leu-Asn-(P-F-Phe)-Nh2
PDB1OKVAChain A, Cyclin A Binding Groove Inhibitor H-arg-arg-leu-ile-phe-nh2
PDB1KE9AChain A, Cyclin-Dependent Kinase 2 (Cdk2) Complexed With 3-{[4- ({[amino(Imino)methyl]aminosulfonyl)anilino]methylene}-2- Oxo-2,3-Dihydro-1h-Indole
PDB1KE8A Chain A, Cyclin-Dependent Kinase 2 (Cdk2) Complexed With 4-{[(2-Oxo- 1,2-Dihydro-3h-Indol-3-Ylidene)methyl]amino}-N-(1,3- Thiazol-2-Yl)benzenesulfonamide
PDB1PXPA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor N-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]- N',N'-Dimethyl-Benzene-1,4-Diamine
PDB1PXLAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor [4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]- (4-trifluoromethyl-phenyl)-amine
PDB1OL2C Chain C, Cyclin A Binding Groove Inhibitor H-Arg-Arg-Leu-Asn- (P-F-Phe)-Nh2
PDB1OKVC Chain C, Cyclin A Binding Groove Inhibitor H-Arg-Arg-Leu-Ile-Phe-Nh2
PDB1PXLA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor [4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]- (4-Trifluoromethyl-Phenyl)-Amine
PDB1OL1CChain C, Cyclin A Binding Groove Inhibitor H-Cit-Cit-Leu-Ile-(P-F-Phe)-Nh2
PDB1OIQA Chain A, Imidazopyridines: A Potent And Selective Class Of Cyclin- Dependent Kinase Inhibitors Identified Through Structure- Based Hybridisation
PDB1OIQAChain A, Imidazopyridines: A Potent And Selective Class Of Cyclin- Dependent Kinase Inhibitors Identified Through Structure- Based Hybridisation
PDB1PYEAChain A, Crystal Structure Of Cdk2 With Inhibitor
PDB1PYEA Chain A, Crystal Structure Of Cdk2 With Inhibitor
PDB1PXOAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor [4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2- Yl]-(3-Nitro-Phenyl)-Amine
PDB1PXOA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor [4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2- Yl]-(3-Nitro-Phenyl)-Amine
PDB1PXNA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)- Pyrimidin-2-Ylamino]-Phenol
PDB1PXMAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2- Ylamino]-Phenol
PDB1PXKAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor N-[4-(2,4-dimethyl-thiazol-5-yl)pyrimidin-2-yl]- N'-hydroxyiminoformamide
PDB1PXKA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor N-[4-(2,4-Dimethyl-Thiazol-5-Yl)pyrimidin-2-Yl]- N'-Hydroxyiminoformamide
PDB1PXJA Chain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine
PDB1PXIAChain A, Human Cyclin Dependent Kinase 2 Complexed With The Inhibitor 4-(2,5-dichloro-thiophen-3-yl)-pyrimidin-2- Ylamine
PDB1PW2AChain A, Apo Structure Of Human Cyclin-Dependent Kinase 2
PDB1PW2A Chain A, Apo Structure Of Human Cyclin-Dependent Kinase 2
PDB1P2AA Chain A, The Structure Of Cyclin Dependent Kinase 2 (Ckd2) With A Trisubstituted Naphthostyril Inhibitor
PDB1OL2CChain C, Cyclin A Binding Groove Inhibitor H-Arg-Arg-Leu-Asn-(P-F-Phe)-Nh2
PDB1OL1C Chain C, Cyclin A Binding Groove Inhibitor H-Cit-Cit-Leu-Ile- (P-F-Phe)-Nh2
PDB1OKWC Chain C, Cyclin A Binding Groove Inhibitor Ac-Arg-Arg-Leu-Asn- (M-Cl-Phe)-Nh2
PDB1OKVCChain C, Cyclin A Binding Groove Inhibitor H-arg-arg-leu-ile-phe-nh2
UCSCGenomeBrowserP24941 
UCSCGenomeBrowserENSPTRT00000009330.1 
ENSEMBLENSP00000266970 
ENSEMBLENSPTRP00000008631 
ENSEMBLENSP00000266970TDI sequence
ENSEMBLGENSCAN00000011141 
ENSEMBLENSP00000266970