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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link A4QPA9
Original Database ID EN ENSP00000302486.4
Organism Pteropus alecto, Callithrix jacchus, etc.
Annotation subname: full=mitogen-activated
protein kinase kinase 1;subname:
full=mitogen-ac tivated protein
kinase kinase 1, isoform cra_a;subname:
full=cdna flj ...
Sequence Length 393

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region39-382
Protein Length393
Template PDB Code3eqcA
Template Region39-382
Sequence Identity100%
E-Value0
GA3411
MPQS1.96032
z-DOPE-1.16
TSVMod MethodMSALL
TSVMod RMSD1.513
TSVMod NO350.954
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Template Structure
PDB3eqcx-ray structure of the human mitogen-activated protein kinase kinase 1 (mek1) in a ternary complex with compound 1, atp-gs and mg2p
DBALI3eqcA 
JenaImageLibrary3eqc 
Target Sequence
UniProtKBQ0VD16SubName: Full=MAP2K1 protein {ECO:0000313|EMBL:AAI19887.2};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSBTAP00000045293};
InterProQ0VD16 
PFAMQ0VD16 
ProdomQ0VD16 
UniProtKBL5K149SubName: Full=Dual specificity mitogen-activated protein kinase kinase 1 {ECO:0000313|EMBL:ELK05310.1};
InterProL5K149 
PFAML5K149 
ProdomL5K149 
UniProtKBH2Q9N2SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 1 {ECO:0000313|Ensembl:ENSPTRP00000012302};SubName: Full=Mitogen-activated protein kinase kinase 1 {ECO:0000313|EMBL:JAA09397.1};
InterProH2Q9N2 
PFAMH2Q9N2 
ProdomH2Q9N2 
UniProtKBG1RR24SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000015688};
InterProG1RR24 
PFAMG1RR24 
ProdomG1RR24 
UniProtKBH0XE68SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOGAP00000014222};
InterProH0XE68 
PFAMH0XE68 
ProdomH0XE68 
UniProtKBG3QM92SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000003627};
InterProG3QM92 
PFAMG3QM92 
ProdomG3QM92 
UniProtKBA4QPA9SubName: Full=Mitogen-activated protein kinase kinase 1 {ECO:0000313|EMBL:AAI39730.1};SubName: Full=Mitogen-activated protein kinase kinase 1, isoform CRA_a {ECO:0000313|EMBL:EAW77765.1};SubName: Full
InterProA4QPA9 
PFAMA4QPA9 
ProdomA4QPA9 
UniProtKBF2Z4G4SubName: Full=MAP2K1 protein {ECO:0000313|EMBL:AAI19887.2};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSBTAP00000045293};
InterProF2Z4G4 
PFAMF2Z4G4 
ProdomF2Z4G4 
UniProtKBQ02750RecName: Full=Dual specificity mitogen-activated protein kinase kinase 1;Short=MAP kinase kinase 1;Short=MAPKK 1;Short=MKK1;EC=2.7.12.2;AltName: Full=ERK activator kinase 1;AltName: Full=MAPK/ERK kina
InterProQ02750 
PFAMQ02750 
ProdomQ02750 
UniProtKBF6XQS5SubName: Full=Dual specificity mitogen-activated protein kinase kinase 1 {ECO:0000313|EMBL:JAB06971.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCJAP00000013904};
InterProF6XQS5 
PFAMF6XQS5 
ProdomF6XQS5 
UniProtKBA0A4W2D4M5Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A4W2D4M5 
PFAMA0A4W2D4M5 
ProdomA0A4W2D4M5 
UniProtKBA0A2R9A4U3Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2R9A4U3 
PFAMA0A2R9A4U3 
ProdomA0A2R9A4U3 
UniProtKBA0A452FI55Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A452FI55 
PFAMA0A452FI55 
ProdomA0A452FI55 
UniProtKBA0A5E4C9G4Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A5E4C9G4 
PFAMA0A5E4C9G4 
ProdomA0A5E4C9G4 
UniProtKBA0A6D2Y129SubName: Full=MAP2K1 isoform 1 {ECO:0000313|EMBL:PNI74267.1}
InterProA0A6D2Y129 
PFAMA0A6D2Y129 
ProdomA0A6D2Y129 
UniProtKBA0A6J0W498SubName: Full=dual specificity mitogen-activated protein kinase kinase 1 {ECO:0000313|RefSeq:XP_020732513.1}
InterProA0A6J0W498 
PFAMA0A6J0W498 
ProdomA0A6J0W498 
UniProtKBA0A2K6SZ10SubName: Full=Mitogen-activated protein kinase kinase 1 {ECO:0000313|Ensembl:ENSSBOP00000012637}
InterProA0A2K6SZ10 
PFAMA0A2K6SZ10 
ProdomA0A2K6SZ10 
UniProtKBA0A6J3FNR8SubName: Full=dual specificity mitogen-activated protein kinase kinase 1 isoform X1 {ECO:0000313|RefSeq:XP_032106942.1}
InterProA0A6J3FNR8 
PFAMA0A6J3FNR8 
ProdomA0A6J3FNR8 
UniProtKBA0A6P3H1F9SubName: Full=dual specificity mitogen-activated protein kinase kinase 1 isoform X1 {ECO:0000313|RefSeq:XP_010832837.1}
InterProA0A6P3H1F9 
PFAMA0A6P3H1F9 
ProdomA0A6P3H1F9 
UniProtKBF6XQS5SubName: Full=Uncharacterized protein;
InterProF6XQS5 
PFAMF6XQS5 
ProdomF6XQS5 
UniProtKBG1RR24SubName: Full=Uncharacterized protein;
InterProG1RR24 
PFAMG1RR24 
ProdomG1RR24 
UniProtKBA4QPA9SubName: Full=Mitogen-activated protein kinase kinase 1;SubName: Full=Mitogen-activated protein kinase kinase 1, isoform CRA_a;SubName: Full=cDNA FLJ76051, highly similar to Homo sapiens mitogen-activ
InterProA4QPA9 
PFAMA4QPA9 
ProdomA4QPA9 
UniProtKBA0A8D2KLL3SubName: Full=Mitogen-activated protein kinase kinase 1 {ECO:0000313|Ensembl:ENSUPAP00010022868}
InterProA0A8D2KLL3 
PFAMA0A8D2KLL3 
ProdomA0A8D2KLL3 
UniProtKBA0A8D2DYJ8SubName: Full=Mitogen-activated protein kinase kinase 1 {ECO:0000313|Ensembl:ENSSVLP00005031356}
InterProA0A8D2DYJ8 
PFAMA0A8D2DYJ8 
ProdomA0A8D2DYJ8 
UniProtKBA0A8C3WV68SubName: Full=Mitogen-activated protein kinase kinase 1 {ECO:0000313|Ensembl:ENSCWAP00000020266}
InterProA0A8C3WV68 
PFAMA0A8C3WV68 
ProdomA0A8C3WV68 
UniProtKBA0A8B9YVX2SubName: Full=Mitogen-activated protein kinase kinase 1 {ECO:0000313|Ensembl:ENSBGRP00000039305}
InterProA0A8B9YVX2 
PFAMA0A8B9YVX2 
ProdomA0A8B9YVX2 
UniProtKBA0A6P5CDE2SubName: Full=dual specificity mitogen-activated protein kinase kinase 1 isoform X1 {ECO:0000313|RefSeq:XP_019823715.1}
InterProA0A6P5CDE2 
PFAMA0A6P5CDE2 
ProdomA0A6P5CDE2 
UniProtKBA0A6P3YIM5SubName: Full=dual specificity mitogen-activated protein kinase kinase 1 isoform X1 {ECO:0000313|RefSeq:XP_014952319.2}
InterProA0A6P3YIM5 
PFAMA0A6P3YIM5 
ProdomA0A6P3YIM5 
UniProtKBA0A6P3S323SubName: Full=dual specificity mitogen-activated protein kinase kinase 1 isoform X1 {ECO:0000313|RefSeq:XP_011384342.1}
InterProA0A6P3S323 
PFAMA0A6P3S323 
ProdomA0A6P3S323 
UniProtKBF2Z4G4SubName: Full=MAP2K1 protein;SubName: Full=Uncharacterized protein;
InterProF2Z4G4 
PFAMF2Z4G4 
ProdomF2Z4G4 
UniProtKBA0A2J8NR99SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 1 {ECO:0000313|Ensembl:ENSPTRP00000063228}SubName: Full=Mitogen-activated protein kinase kinase 1 {ECO:0000313|EMBL:JAA09397.1}
InterProA0A2J8NR99 
PFAMA0A2J8NR99 
ProdomA0A2J8NR99 
UniProtKBA0A2I3RF04SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 1 {ECO:0000313|Ensembl:ENSPTRP00000063228}SubName: Full=Mitogen-activated protein kinase kinase 1 {ECO:0000313|EMBL:JAA09397.1}
InterProA0A2I3RF04 
PFAMA0A2I3RF04 
ProdomA0A2I3RF04 
UniProtKBA0A2I3GXI0Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2I3GXI0 
PFAMA0A2I3GXI0 
ProdomA0A2I3GXI0 
UniProtKBA0A9N7A6D0Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A9N7A6D0 
PFAMA0A9N7A6D0 
ProdomA0A9N7A6D0 
UniProtKBA0A8D1H8V1SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00045011641}
InterProA0A8D1H8V1 
PFAMA0A8D1H8V1 
ProdomA0A8D1H8V1 
UniProtKBQ0VD16SubName: Full=MAP2K1 protein;SubName: Full=Uncharacterized protein;
InterProQ0VD16 
PFAMQ0VD16 
ProdomQ0VD16 
UniProtKBH2Q9N2SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 1;
InterProH2Q9N2 
PFAMH2Q9N2 
ProdomH2Q9N2 
UniProtKBU3CZR8SubName: Full=Dual specificity mitogen-activated protein kinase kinase 1 {ECO:0000313|EMBL:JAB06971.1}
InterProU3CZR8 
PFAMU3CZR8 
ProdomU3CZR8 
UniProtKBG3QM92SubName: Full=Uncharacterized protein;
InterProG3QM92 
PFAMG3QM92 
ProdomG3QM92 
UniProtKBA0A287BK75SubName: Full=Dual specificity mitogen-activated protein kinase kinase 1 {ECO:0000313|EMBL:HDA38998.1}
InterProA0A287BK75 
PFAMA0A287BK75 
ProdomA0A287BK75 
UniProtKBH0XE68SubName: Full=Uncharacterized protein;
InterProH0XE68 
PFAMH0XE68 
ProdomH0XE68 
UniProtKBQ02750.2MP2K1_HUMAN RecName: Full=Dual specificity mitogen-activated protein kinase kinase 1; Short=MAP kinase kinase 1; Short=MAPKK 1; AltName: Full=ERK activator kinase 1; AltName: Full=MAPK/ERK kinase 1; S
InterProQ02750.2 
PFAMQ02750.2 
ProdomQ02750.2 
UniProtKBQ02750RecName: Full=Dual specificity mitogen-activated protein kinase kinase 1;Short=MAP kinase kinase 1;Short=MAPKK 1;Short=MKK1;EC=2.7.12.2;AltName: Full=ERK activator kinase 1;AltName: Full=MAPK/ERK kina
InterProQ02750 
PFAMQ02750 
ProdomQ02750 
RefSeqXP_039721175.1dual specificity mitogen-activated protein kinase kinase 1 isoform X1
RefSeqXP_036788171.1dual specificity mitogen-activated protein kinase kinase 1
RefSeqXP_040081746.1dual specificity mitogen-activated protein kinase kinase 1 isoform X1
RefSeqXP_032031523.1dual specificity mitogen-activated protein kinase kinase 1
RefSeqXP_031308752.1dual specificity mitogen-activated protein kinase kinase 1
RefSeqXP_027779977.1dual specificity mitogen-activated protein kinase kinase 1
RefSeqXP_037358659.1dual specificity mitogen-activated protein kinase kinase 1 isoform X2
RefSeqXP_027408828.1dual specificity mitogen-activated protein kinase kinase 1 isoform X1
RefSeqXP_026264596.1dual specificity mitogen-activated protein kinase kinase 1 isoform X1
RefSeqXP_016064131.1PREDICTED: dual specificity mitogen-activated protein kinase kinase 1
RefSeqXP_006050282.1dual specificity mitogen-activated protein kinase kinase 1
RefSeqXP_002753305.1 PREDICTED: dual specificity mitogen-activated protein kinase kinase 1 [Callithrix jacchus]
RefSeqXP_040092555.1dual specificity mitogen-activated protein kinase kinase 1 isoform X1
RefSeqNP_002746.1 dual specificity mitogen-activated protein kinase kinase 1 [Homo sapiens]
RefSeqNP_001124224.1 dual specificity mitogen-activated protein kinase kinase 1 [Bos taurus]
RefSeqXP_013374406.1PREDICTED: dual specificity mitogen-activated protein kinase kinase 1
PDB7MFDBDual specificity mitogen-activated protein kinase kinase 1
GenPept119598171mitogen-activated protein kinase kinase 1, isoform CRA_a
GenPept261860392mitogen-activated protein kinase kinase 1, partial
GenPept296213521 PREDICTED: dual specificity mitogen-activated protein kinase kinase 1 [Callithrix jacchus]
GenPept296483644 mitogen-activated protein kinase kinase 1 [Bos taurus]
GenPept314264517Sequence 28 from patent US 7763425
GenPept31691339Sequence 11 from patent US 6541605
GenPept346266A45100 mitogen-activated protein kinase kinase (EC 2.7.1.-) 1, splice form A - human
GenPept2491525I64375 Sequence 33 from patent US 5663314
GenPept195539553 dual specificity mitogen-activated protein kinase kinase 1 [Bos taurus]
GenPept188569MAP kinase kinase
GenPept187953569Mitogen-activated protein kinase kinase 1
GenPept158455119MAP2K1 protein
GenPept158256432unnamed protein product
GenPept15102963Sequence 11 from patent US 6174676
GenPept14477828Sequence 11 from patent US 6136596
GenPept141796928Mitogen-activated protein kinase kinase 1
GenPept375661051Sequence 22 from patent US 8088589
GenPept380287547Sequence 22 from patent US 8129125
GenPept3991116AR000966 Sequence 11 from patent US 5736381
GenPept757047103Sequence 22 from patent US 8900820
GenPept756521883Sequence 22 from patent US 8741559
GenPept756521766Sequence 164 from patent US 8741556
GenPept756322239Sequence 118 from patent US 8680041
GenPept5579478 dual specificity mitogen-activated protein kinase kinase 1 [Homo sapiens]
GenPept508103451Sequence 12 from patent US 8440443
GenPept431895892Dual specificity mitogen-activated protein kinase kinase 1
GenPept40091398Sequence 11 from patent US 6610523
GenPept400274MP2K1_HUMAN RecName: Full=Dual specificity mitogen-activated protein kinase kinase 1; Short=MAP kinase kinase 1; Short=MAPKK 1; AltName: Full=ERK activator kinase 1; AltName: Full=MAPK/ERK kinase 1; S
GenBankDAA25759.1 mitogen-activated protein kinase kinase 1 [Bos taurus]
GenBankAAI39730.1 Mitogen-activated protein kinase kinase 1 [Homo sapiens]
GenBankAAI37460.1 Mitogen-activated protein kinase kinase 1 [Homo sapiens]
GenBankAAI19887.2 MAP2K1 protein [Bos taurus]
GenBankAAA36318.1 MAP kinase kinase [Homo sapiens]
GenBankEAW77765.1 mitogen-activated protein kinase kinase 1, isoform CRA_a [Homo sapiens]
ENSEMBLENSP00000302486Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.1.-) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1). [Homo sapiens]
UCSCGenomeBrowserQ02750 
UCSCGenomeBrowserENSPTRT00000013275.1 
ENSEMBLENSP00000302486 
ENSEMBLENSPTRP00000012302 
ENSEMBLENSP00000302486TDI sequence
ENSEMBLENSP00000302486