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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P10912
Original Database ID EN ENSP00000230882.4
Organism Homo sapiens
Annotation recname: full=growth hormone receptor;short=gh
receptor;altname: full=somatotrop
in receptor;contains:recname:
full=growth hormone-binding protein;sho
...
Sequence Length 638
 

SNP Information

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ResidueAA-Residue
Variants
InterfaceLigandStabilityValidated
rs6413484 V162 VF * X
rs6181 R179 RH   X
rs6177 R229 RH  
7 SNPs found but only 3 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1axistructural plasticity at the hgh:hghbp interface ; PFAM: PF00041 PF00103 ; SCOP: 21997 21998
DBALI1axiB 
CATH2.60.40.10 Domain: 1axiB01 Immunoglobulins (100%)
CATH2.60.40.10 Domain: 1axiB02 Immunoglobulins (100%)
JenaImageLibrary1axi 
Target Sequence
UniProtKBQ9HCX2RecName: Full=Growth hormone receptor;Short=GH receptor;AltName: Full=Somatotropin receptor;Contains:RecName: Full=Growth hormone-binding protein;Short=GH-binding protein;Short=GHBP;AltName: Full=Seru
InterProQ9HCX2 
PFAMQ9HCX2 
ProdomQ9HCX2 
UniProtKBP10912RecName: Full=Growth hormone receptor;Short=GH receptor;AltName: Full=Somatotropin receptor;Contains:RecName: Full=Growth hormone-binding protein;Short=GH-binding protein;Short=GHBP;AltName: Full=Seru
InterProP10912 
PFAMP10912 
ProdomP10912 
UniProtKBQ9HCX2RecName: Full=Growth hormone receptor;Short=GH receptor;AltName: Full=Somatotropin receptor;Contains:RecName: Full=Growth hormone-binding protein;Short=GH-binding protein;Short=GHBP;AltName: Full=Seru
InterProQ9HCX2 
PFAMQ9HCX2 
ProdomQ9HCX2 
UniProtKBP10912.1GHR_HUMAN RecName: Full=Growth hormone receptor; Short=GH receptor; AltName: Full=Somatotropin receptor; Contains: RecName: Full=Growth hormone-binding protein; Short=GH-binding protein; Short=GHBP; A
InterProP10912.1 
PFAMP10912.1 
ProdomP10912.1 
UniProtKBP10912RecName: Full=Growth hormone receptor;Short=GH receptor;AltName: Full=Somatotropin receptor;Contains:RecName: Full=Growth hormone-binding protein;Short=GH-binding protein;Short=GHBP;AltName: Full=Seru
InterProP10912 
PFAMP10912 
ProdomP10912 
RefSeqNP_000154.1 growth hormone receptor precursor [Homo sapiens]
GenPept88618S04530 somatotropin receptor, hepatic precursor - human
GenPept583353612unnamed protein product
GenPept568655140Sequence 21 from patent US 8613929
GenPept50832232unnamed protein product
GenPept4503993 growth hormone receptor precursor [Homo sapiens]
GenPept121180GHR_HUMAN RecName: Full=Growth hormone receptor; Short=GH receptor; AltName: Full=Somatotropin receptor; Contains: RecName: Full=Growth hormone-binding protein; Short=GH-binding protein; Short=GHBP; A
GenPept126468541unnamed protein product
GenPept270287Sequence 5 from Patent US 4857637
GenPept283915527unnamed protein product
GenPept284806899unnamed protein product
GenPept31738unnamed protein product
GenPept348083154Sequence 21 from patent US 8026209
GenPept119576427growth hormone receptor
GenBankEAW56023.1 growth hormone receptor [Homo sapiens]
ENSEMBLENSP00000230882Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone binding protein (GH binding protein) (GHBP) (Serum binding protein)]. [Homo sapiens]
EMBLCAA29808.1 
ENSEMBLENSP00000230882 
ENSEMBLENSP00000230882TDI sequence
ENSEMBLENSP00000230882 
UCSCGenomeBrowserP10912