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ModBase: Database of Comparative Protein Structure Models

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Sequence Information

Primary Database Link O95278
Original Database ID EN ENSP00000356489.3
Organism Homo sapiens
Annotation laforin (progressive myoclonus
epilepsy type 2)
Sequence Length 331

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region1-325
Protein Length331
Template PDB Code4rkkA
Template Region1-325
Sequence Identity100%
E-Value0
GA3411
MPQS2.19337
z-DOPE-1.48
TSVMod MethodMSALL
TSVMod RMSD0.507
TSVMod NO350.964
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in advanced pancreatic tumor for CCDS5206.1 R108C
Template Structure
PDB4rkk
DBALI4rkkA 
JenaImageLibrary4rkk 
Target Sequence
UniProtKBQ9UEN2RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ9UEN2 
PFAMQ9UEN2 
ProdomQ9UEN2 
UniProtKBQ9BS66RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ9BS66 
PFAMQ9BS66 
ProdomQ9BS66 
UniProtKBQ8IX25RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ8IX25 
PFAMQ8IX25 
ProdomQ8IX25 
UniProtKBO95278LAFORIN (PROGRESSIVE MYOCLONUS epilepsy type 2)
InterProO95278 
PFAMO95278 
ProdomO95278 
UniProtKBQ5T3F5SubName: Full=Epilepsy, progressive myoclonus type 2A, Lafora disease (Laforin) (Epilepsy, progressive myoclonus type 2A, Lafora disease (Laforin), isoform CRA_b);
InterProQ5T3F5 
PFAMQ5T3F5 
ProdomQ5T3F5 
UniProtKBQ5THQ4Epilepsy, progressive myoclonus type 2A, Lafora disease (Laforin)(Epilepsy, progressive myoclonus type 2A, Lafora disease (Laforin),isoform CRA_b).
InterProQ5THQ4 
PFAMQ5THQ4 
ProdomQ5THQ4 
UniProtKBQ8IX24RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ8IX24 
PFAMQ8IX24 
ProdomQ8IX24 
UniProtKBQ9UEN2RecName: Full=Laforin;EC=3.1.3.-;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Glucan phosphatase;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ9UEN2 
PFAMQ9UEN2 
ProdomQ9UEN2 
UniProtKBO95278RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProO95278 
PFAMO95278 
ProdomO95278 
UniProtKBO95278.2EPM2A_HUMAN RecName: Full=Laforin; AltName: Full=Lafora PTPase; Short=LAFPTPase
InterProO95278.2 
PFAMO95278.2 
ProdomO95278.2 
UniProtKBO95483RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProO95483 
PFAMO95483 
ProdomO95483 
UniProtKBQ9BS66RecName: Full=Laforin;EC=3.1.3.-;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Glucan phosphatase;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ9BS66 
PFAMQ9BS66 
ProdomQ9BS66 
UniProtKBQ5T3F5RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ5T3F5 
PFAMQ5T3F5 
ProdomQ5T3F5 
UniProtKBQ8IX25RecName: Full=Laforin;EC=3.1.3.-;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Glucan phosphatase;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ8IX25 
PFAMQ8IX25 
ProdomQ8IX25 
UniProtKBQ8IU96RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ8IU96 
PFAMQ8IU96 
ProdomQ8IU96 
RefSeqNP_005661.1 laforin isoform a [Homo sapiens]
GenPept10505185AF284580_1 progressive myoclonus epilepsy type 2
GenPept56205604epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
GenPept50400258EPM2A_HUMAN RecName: Full=Laforin; AltName: Full=Lafora PTPase; Short=LAFPTPase
GenPept56202640epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
GenPept353304860Sequence 125 from patent US 8039210
GenPept56666740Sequence 2 from patent US 6825328
GenPept6005986laforin
GenPept757872457Sequence 2 from patent US 8486624
GenPept915840006Sequence 125 from patent US 9012145
GenPept259183746Sequence 2 from patent US 7550571
GenPept12731903 epilepsy, progressive myoclonus type 2, Lafora disease (laforin) [Homo sapiens]
GenPept119568229epilepsy, progressive myoclonus type 2A, Lafora disease (laforin), isoform CRA_b
GenPept11321613 laforin isoform a [Homo sapiens]
GenPept414902967Sequence 275 from patent US 8298775
GenBankEAW47844.1 epilepsy, progressive myoclonus type 2A, Lafora disease (laforin), isoform CRA_b [Homo sapiens]
GenBankAAC83347.2 laforin [Homo sapiens]
GenBankAAG18377.1AF284580_1 progressive myoclonus epilepsy type 2 [Homo sapiens]
ENSEMBLENSP00000262907Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase). [Homo sapiens]
EMBLCAI21419.1 
EMBLCAI21675.1 
UCSCGenomeBrowserO95278 
ENSEMBLENSP00000262907 
ENSEMBLENSP00000262907TDI sequence
ENSEMBLENSP00000356489