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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link Q5R5M7.1
Original Database ID EN ENSP00000251849.4
Organism Cercocebus atys, Cercocebus torquatus atys, etc.
Annotation raf1_ponab recname: full=raf proto-oncogene
serine/threonine-protein kinase;
alt name: full=proto-oncogene
c-raf; short=craf; altname: full=raf-1
Sequence Length 648
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs3729929 E425 EQ   *
rs3730273 M409 MV  
rs5746220 P308 PL  
rs3730271 S259 SP  
5 SNPs found but only 4 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1fmkcrystal structure of human tyrosine-protein kinase c-src ; EC: 2.7.1.112 ; PFAM: PF00017 PF00018 PF00069 ; SCOP: 24511 40436 41690
DBALI1fmkA 
CATH3.30.505.10 Domain: 1fmkA02 SHC Adaptor Protein (100%)
CATH3.30.200.20 Domain: 1fmkA03 Phosphorylase Kinase; domain 1 (100%)
CATH1.10.510.10 Domain: 1fmkA04 Transferase(Phosphotransferase) domain 1 (99%)
JenaImageLibrary1fmk 
Target Sequence
UniProtKBM3ZCA6SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000024343};
InterProM3ZCA6 
PFAMM3ZCA6 
ProdomM3ZCA6 
UniProtKBB0LPH8RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProB0LPH8 
PFAMB0LPH8 
ProdomB0LPH8 
UniProtKBQ9UC20RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProQ9UC20 
PFAMQ9UC20 
ProdomQ9UC20 
UniProtKBQ15278RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProQ15278 
PFAMQ15278 
ProdomQ15278 
UniProtKBQ5R5M7RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProQ5R5M7 
PFAMQ5R5M7 
ProdomQ5R5M7 
UniProtKBB2R5N3RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProB2R5N3 
PFAMB2R5N3 
ProdomB2R5N3 
UniProtKBF6SWC0SubName: Full=RAF proto-oncogene serine/threonine-protein kinase {ECO:0000313|EMBL:AFE64298.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000009777};
InterProF6SWC0 
PFAMF6SWC0 
ProdomF6SWC0 
UniProtKBP04049RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProP04049 
PFAMP04049 
ProdomP04049 
UniProtKBL7RRS6SubName: Full=V-raf-1 murine leukemia viral oncogene homolog 1 {ECO:0000313|EMBL:AGC09606.1};SubName: Full=V-raf-1 murine leukemia viral oncogene homolog 1, isoform CRA_a;
InterProL7RRS6 
PFAML7RRS6 
ProdomL7RRS6 
UniProtKBA0A096NYS4RecName: Full=Protein kinase C {ECO:0000256|SAAS:SAAS00253193};EC=2.7.11.13 {ECO:0000256|SAAS:SAAS00253193};
InterProA0A096NYS4 
PFAMA0A096NYS4 
ProdomA0A096NYS4 
UniProtKBQ5R5M7Hypothetical protein DKFZp469F0314
InterProQ5R5M7 
PFAMQ5R5M7 
ProdomQ5R5M7 
UniProtKBF6SWC0SubName: Full=RAF proto-oncogene serine/threonine-protein kinase;SubName: Full=Uncharacterized protein;
InterProF6SWC0 
PFAMF6SWC0 
ProdomF6SWC0 
UniProtKBA0A8D2FDX4SubName: Full=Raf-1 proto-oncogene, serine/threonine kinase {ECO:0000313|Ensembl:ENSTGEP00000019306}
InterProA0A8D2FDX4 
PFAMA0A8D2FDX4 
ProdomA0A8D2FDX4 
UniProtKBB0LPH8V-raf-1 murine leukemia viral oncogene homolog 1 (V-raf-1 murineleukemia viral oncogene homolog 1, isoform CRA_a).
InterProB0LPH8 
PFAMB0LPH8 
ProdomB0LPH8 
UniProtKBA0A2K6DFP8Non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513}EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513}
InterProA0A2K6DFP8 
PFAMA0A2K6DFP8 
ProdomA0A2K6DFP8 
UniProtKBA0A2K5MHK1Non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513}EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513}
InterProA0A2K5MHK1 
PFAMA0A2K5MHK1 
ProdomA0A2K5MHK1 
UniProtKBA0A2J8TVZ9Non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513}EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513}
InterProA0A2J8TVZ9 
PFAMA0A2J8TVZ9 
ProdomA0A2J8TVZ9 
UniProtKBA0A024R2G5Non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513}EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513}
InterProA0A024R2G5 
PFAMA0A024R2G5 
ProdomA0A024R2G5 
UniProtKBB2R5N3RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProB2R5N3 
PFAMB2R5N3 
ProdomB2R5N3 
UniProtKBB0LPH8RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProB0LPH8 
PFAMB0LPH8 
ProdomB0LPH8 
UniProtKBQ5R5M7.1RAF1_PONAB RecName: Full=RAF proto-oncogene serine/threonine-protein kinase; AltName: Full=Proto-oncogene c-RAF; Short=cRaf; AltName: Full=Raf-1
InterProQ5R5M7.1 
PFAMQ5R5M7.1 
ProdomQ5R5M7.1 
UniProtKBQ5R5M7RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProQ5R5M7 
PFAMQ5R5M7 
ProdomQ5R5M7 
UniProtKBP04049RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProP04049 
PFAMP04049 
ProdomP04049 
UniProtKBP04049.1RAF1_HUMAN RecName: Full=RAF proto-oncogene serine/threonine-protein kinase; AltName: Full=Proto-oncogene c-RAF; Short=cRaf; AltName: Full=Raf-1
InterProP04049.1 
PFAMP04049.1 
ProdomP04049.1 
UniProtKBQ15278RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProQ15278 
PFAMQ15278 
ProdomQ15278 
UniProtKBQ9UC20RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;EC=2.7.11.1;AltName: Full=Proto-oncogene c-RAF;Short=cRaf;AltName: Full=Raf-1;
InterProQ9UC20 
PFAMQ9UC20 
ProdomQ9UC20 
RefSeqXP_025233631.1RAF proto-oncogene serine/threonine-protein kinase isoform X2
RefSeqXP_030865419.1RAF proto-oncogene serine/threonine-protein kinase isoform X1
RefSeqNP_001126730.1 RAF proto-oncogene serine/threonine-protein kinase [Pongo abelii]
RefSeqXP_032005642.1RAF proto-oncogene serine/threonine-protein kinase isoform X1
RefSeqXP_025233630.1RAF proto-oncogene serine/threonine-protein kinase isoform X2
RefSeqXP_021789869.1RAF proto-oncogene serine/threonine-protein kinase isoform X2
RefSeqNP_001341619.1RAF proto-oncogene serine/threonine-protein kinase isoform b
RefSeqXP_007983458.2RAF proto-oncogene serine/threonine-protein kinase isoform X1
RefSeqXP_001086154.1 PREDICTED: RAF proto-oncogene serine/threonine-protein kinase isoform 2 [Macaca mulatta]
RefSeqNP_002871.1 RAF proto-oncogene serine/threonine-protein kinase [Homo sapiens]
RefSeqXP_037859453.1RAF proto-oncogene serine/threonine-protein kinase isoform X1
GenPept109034318 PREDICTED: RAF proto-oncogene serine/threonine-protein kinase isoform 2 [Macaca mulatta]
GenPept2095933Sequence 12 from patent US 5618670
GenPept21387246unnamed protein product
GenPept29419512unnamed protein product
GenPept294600021Sequence 12 from patent US 7691599
GenPept30016945v-raf-1 murine leukemia viral oncogene homolog 1
GenPept34605642Sequence 1 from patent US 6300081
GenPept35842unnamed protein product
GenPept380784845RAF proto-oncogene serine/threonine-protein kinase
GenPept383420445RAF proto-oncogene serine/threonine-protein kinase
GenPept197102540 RAF proto-oncogene serine/threonine-protein kinase [Pongo abelii]
GenPept1831738Sequence 2 from patent US 5597719
GenPept119584538v-raf-1 murine leukemia viral oncogene homolog 1, isoform CRA_a
GenPept119584539v-raf-1 murine leukemia viral oncogene homolog 1, isoform CRA_a
GenPept125651RAF1_HUMAN RecName: Full=RAF proto-oncogene serine/threonine-protein kinase; AltName: Full=Proto-oncogene c-RAF; Short=cRaf; AltName: Full=Raf-1
GenPept12827406Sequence 13 from patent US 6114517
GenPept14730790 v-raf-1 murine leukemia viral oncogene homolog 1 [Homo sapiens]
GenPept155076342Sequence 55 from patent US 7202033
GenPept166706819v-raf-1 murine leukemia viral oncogene homolog 1
GenPept168277678RAF proto-oncogene serine/threonine-protein kinase, partial
GenPept17390263V-raf-1 murine leukemia viral oncogene homolog 1
GenPept384948566RAF proto-oncogene serine/threonine-protein kinase
GenPept397038173Sequence 2 from patent US 8221979
GenPept42711885Sequence 3 from patent US 6689560
GenPept75070482RAF1_PONAB RecName: Full=RAF proto-oncogene serine/threonine-protein kinase; AltName: Full=Proto-oncogene c-RAF; Short=cRaf; AltName: Full=Raf-1
GenPept66762TVHUF6 protein kinase raf-1 (EC 2.7.1.-) - human
GenPept649151205RAF1, partial
GenPept60820534v-raf-1 murine leukemia viral oncogene-like 1
GenPept576060879unnamed protein product
GenPept55732477hypothetical protein
GenPept534486363Sequence 101 from patent US 8506948
GenPept4506401 RAF proto-oncogene serine/threonine-protein kinase [Homo sapiens]
GenPept61363318v-raf-1 murine leukemia viral oncogene-like 1
GenPept440503027v-raf-1 murine leukemia viral oncogene homolog 1
GenPept311851678unnamed protein product
GenPept757047278Sequence 5 from patent US 8900845
GenBankABY87557.1 v-raf-1 murine leukemia viral oncogene homolog 1 [Homo sapiens]
GenBankEAW64134.1 v-raf-1 murine leukemia viral oncogene homolog 1, isoform CRA_a [Homo sapiens]
GenBankEAW64135.1 v-raf-1 murine leukemia viral oncogene homolog 1, isoform CRA_a [Homo sapiens]
GenBankAAH18119.1 V-raf-1 murine leukemia viral oncogene homolog 1 [Homo sapiens]
GenBankAAX36539.1 v-raf-1 murine leukemia viral oncogene-like 1 [synthetic construct]
GenBankAAX42370.1 v-raf-1 murine leukemia viral oncogene-like 1 [synthetic construct]
GenBankAAP03432.1 v-raf-1 murine leukemia viral oncogene homolog 1 [Homo sapiens]
ENSEMBLENSP00000251849RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.1.37) (Raf- 1) (C-RAF) (cRaf). [Homo sapiens]
EMBLCAH92939.1 
EMBLCAA27204.1 
UCSCGenomeBrowserP04049 
ENSEMBLENSP00000251849 
ENSEMBLENSP00000251849TDI sequence
ENSEMBLENSP00000251849