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ModBase: Database of Comparative Protein Structure Models

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Sequence Information

Primary Database Link O14666
Original Database ID sp O15111
Organism Homo sapiens
Annotation recname: full=inhibitor of nuclear
factor kappa-b kinase subunit
alpha;short=i-k appa-b kinase
alpha;short=ikbka;short=ikk-alpha;short=ikk-a;short=ika
...
Sequence Length 745

Dataset Information:

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Model Information

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Target Region13-297
Protein Length745
Template PDB Code1o6lA
Template Region150-402
Sequence Identity29%
E-Value8e-49
GA3411
Datasetsnp-human4
ModPipe VersionModPipe1.0
Model Date2006-06-16

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1o6lcrystal structure of an activated akt/protein kinase b (pkb-pif chimera) ternary complex with amp-pnp and gsk3 peptide
DBALI1o6lA 
CATH1.10.510.10 Domain: 1o6lA01 Transferase(Phosphotransferase) domain 1 (86%)
CATH3.30.200.20 Domain: 1o6lA02 Phosphorylase Kinase; domain 1 (39%)
JenaImageLibrary1o6l 
Target Sequence
UniProtKBQ92467RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha;Short=I-kappa-B kinase alpha;Short=IkBKA;Short=IKK-alpha;Short=IKK-A;Short=IkappaB kinase;EC=2.7.11.10;AltName: Full=I-kappa-B ki
InterProQ92467 
PFAMQ92467 
ProdomQ92467 
UniProtKBQ5W0I4RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha;Short=I-kappa-B kinase alpha;Short=IkBKA;Short=IKK-alpha;Short=IKK-A;Short=IkappaB kinase;EC=2.7.11.10;AltName: Full=I-kappa-B ki
InterProQ5W0I4 
PFAMQ5W0I4 
ProdomQ5W0I4 
UniProtKBQ13132RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha;Short=I-kappa-B kinase alpha;Short=IkBKA;Short=IKK-alpha;Short=IKK-A;Short=IkappaB kinase;EC=2.7.11.10;AltName: Full=I-kappa-B ki
InterProQ13132 
PFAMQ13132 
ProdomQ13132 
UniProtKBO15111.1IKKA_HUMAN RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserve
InterProO15111.1 
PFAMO15111.1 
ProdomO15111.1 
UniProtKBO15111RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha;Short=I-kappa-B kinase alpha;Short=IkBKA;Short=IKK-alpha;Short=IKK-A;Short=IkappaB kinase;EC=2.7.11.10;AltName: Full=I-kappa-B ki
InterProO15111 
PFAMO15111 
ProdomO15111 
UniProtKBO14666RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha;Short=I-kappa-B kinase alpha;Short=IkBKA;Short=IKK-alpha;Short=IKK-A;Short=IkappaB kinase;EC=2.7.11.10;AltName: Full=I-kappa-B ki
InterProO14666 
PFAMO14666 
ProdomO14666 
GenPept407102871Sequence 45 from patent US 8263357
GenPept4185273IkB kinase-a
GenPept49066027conserved helix-loop-helix ubiquitous kinase
GenPept5999900Sequence 4 from patent US 5851812
GenPept756757599Sequence 45 from patent US 8815530
GenPept756818690Sequence 480 from patent US 8828944
GenPept756950718Sequence 480 from patent US 8865653
GenPept380289034Sequence 5 from patent US 8129345
GenPept375662595Sequence 8 from patent US 8088915
GenPept33737645Sequence 3 from patent US 6576439
GenPept14285498IKKA_HUMAN RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserve
GenPept15121559Sequence 4 from patent US 6235492
GenPept15121607Sequence 4 from patent US 6235512
GenPept15121609Sequence 4 from patent US 6235513
GenPept155076319Sequence 32 from patent US 7202033
GenPept111978810Sequence 4 from patent US 7045613
GenPept228162380Sequence 1 from patent US 7491506
GenPept2286223IKK-a kinase
GenPept27302388Sequence 4 from patent US 6479266
GenPept281081963Sequence 24 from patent US 7618787
GenPept307685427conserved helix-loop-helix ubiquitous kinase, partial
GenPept314820549Sequence 8 from patent US 7838268
GenPept333689329Sequence 45 from patent US 7943732
GenBankAAD08996.1 IkB kinase-a [Homo sapiens]
GenBankAAT49098.1 conserved helix-loop-helix ubiquitous kinase [Homo sapiens]
GenBankAAC51662.1 IKK-a kinase [Homo sapiens]
UCSCGenomeBrowserO15111