University of California San Francisco | About UCSF | UCSF Benioff Children's Hospital San Francisco

ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link Q5XLC2
Original Database ID EN ENSP00000373240.2
Organism Pan paniscus, Pan troglodytes, etc.
Annotation subname: full=6-phosphofructo-2-kinase/fructose-2,
6-biphosphatase 4 splice isof
orm 5;ec=2.7.1.105;ec=3.1.3.46;subname:
full=fructose-2,6-bisphosphat
...
Sequence Length 434

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

The calculation typically takes 1-2 days, and the results will be added to this page. Registered users will receive an email notification.

Information for additional models of this sequences are available by clicking on the model thumbnails below.  

Model Information

Perform action on this model:

Quality criteria indicate whether the model is considered
reliable (green)
or unreliable (red).
 
Target Region6-417
Protein Length434
Template PDB Code2axnA
Template Region3-455
Sequence Identity70%
E-Value0
GA3411
MPQS1.74651
z-DOPE-1.16
TSVMod MethodMSALL
TSVMod RMSD1.738
TSVMod NO350.937
DatasetH_sapiens_2013_D1
ModPipe VersionSVN.r1513
Model Date2013-10-23

Mouse over the images for more information

Sequence Model Coverage Summary
for all Models of this Sequence:

Filtered models for current sequence (Show all models)

 

Cross-references

Show obsolete/secondary identifiers
Mutation Data
PharmGKB   PharmGKB data available for PFKFB4
Template Structure
PDB2axncrystal structure of the human inducible form 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
DBALI2axnA 
CATH3.40.50.300 Domain: 2axnA01 P-loop containing nucleotide triphosphate hydrolases (100%)
CATH3.40.50.1240 Domain: 2axnA02 Phosphoglycerate mutase-like (100%)
JenaImageLibrary2axn 
Target Sequence
UniProtKBQ5XLC2SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 splice isoform 5;EC=2.7.1.105;EC=3.1.3.46;SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;
InterProQ5XLC2 
PFAMQ5XLC2 
ProdomQ5XLC2 
UniProtKBA0A2R9C0X16-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2R9C0X1 
PFAMA0A2R9C0X1 
ProdomA0A2R9C0X1 
UniProtKBQ5XLC2SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 splice isoform 5;EC=2.7.1.105;EC=3.1.3.46;SubName: Full=Fructose-2,6-bisphosphatase;
InterProQ5XLC2 
PFAMQ5XLC2 
ProdomQ5XLC2 
UniProtKBA0A6D2W3586-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A6D2W358 
PFAMA0A6D2W358 
ProdomA0A6D2W358 
UniProtKBA0A2I3RFQ56-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2I3RFQ5 
PFAMA0A2I3RFQ5 
ProdomA0A2I3RFQ5 
UniProtKBA0A2J8P9W96-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2J8P9W9 
PFAMA0A2J8P9W9 
ProdomA0A2J8P9W9 
RefSeqXP_001158238.1 PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 isoform 5 [Pan troglodytes]
GenPept541120276-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 splice isoform 5
GenPept407103183Sequence 3 from patent US 8263378
GenPept314681617Sequence 3 from patent US 7829682
GenPept114586701 PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 5 [Pan troglodytes]
GenBankAAV28719.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 splice isoform 5 [Homo sapiens]
ENSEMBLENSP00000373240