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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link Q64EX5
Original Database ID REF XP_024309363.1
Organism Pan paniscus, Homo sapiens
Annotation subname: full=6-phosphofructo-2-kinase/fructose-2,
6-biphosphatase 4 splice isof
orm 3;ec=2.7.1.105;ec=3.1.3.46;subname:
full=6-phosphofructo-2-kinase
...
Sequence Length 435

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region4-435
Protein Length435
Template PDB Code1bifA
Template Region37-468
Sequence Identity97%
E-Value0
GA3411
MPQS2.2136
z-DOPE-1.58
TSVMod MethodMTALL
TSVMod RMSD0.782
TSVMod NO350.957
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
PharmGKB   PharmGKB data available for PFKFB4
Template Structure
PDB1bif6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase bifunctional enzyme complexed with atp-g-s and phosphate ; EC: 3.1.3.46 ; PFAM: PF00300 PF01591 ; SCOP: 31961 34003
DBALI1bifA 
CATH3.40.50.300 Domain: 1bifA01 P-loop containing nucleotide triphosphate hydrolases (100%)
CATH3.40.50.1240 Domain: 1bifA02 Phosphoglycerate mutase-like (100%)
JenaImageLibrary1bif 
Target Sequence
UniProtKBQ64EX5SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 splice isoform 3;EC=2.7.1.105;EC=3.1.3.46;SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase-4 isoform 2;EC=2.7.1.1
InterProQ64EX5 
PFAMQ64EX5 
ProdomQ64EX5 
UniProtKBA0A2R9BY446-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2R9BY44 
PFAMA0A2R9BY44 
ProdomA0A2R9BY44 
UniProtKBQ64EX5SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 splice isoform 3;EC=2.7.1.105;EC=3.1.3.46;SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase-4 isoform 2;EC=2.7.1.1
InterProQ64EX5 
PFAMQ64EX5 
ProdomQ64EX5 
RefSeqXP_016796546.16-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X6
RefSeqXP_024309363.16-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X6
GenPept519505966-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 isoform 2
GenPept541120236-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 splice isoform 3
GenBankAAU14998.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 isoform 2 [Homo sapiens]
GenBankAAV28717.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 splice isoform 3 [Homo sapiens]
UCSCGenomeBrowserQ64EX5 
ENSEMBLENSP00000437446