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Sequence Information

Primary Database Link Q16877
Original Database ID EN ENSP00000232375.3
Organism Pan paniscus, Pan troglodytes, etc.
Annotation recname: full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
4;short=6pf-2 -k/fru-2,6-p2ase
4;short=pfk/fbpase 4;altname:
full=6pf-2-k/fru-2,6-p ...
Sequence Length 469

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region38-469
Protein Length469
Template PDB Code1bifA
Template Region37-468
Sequence Identity97%
E-Value0
GA3411
MPQS2.14381
z-DOPE-1.6
TSVMod MethodMTALL
TSVMod RMSD0.791
TSVMod NO350.966
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
PharmGKB   PharmGKB data available for PFKFB4
Template Structure
PDB1bif6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase bifunctional enzyme complexed with atp-g-s and phosphate ; EC: 3.1.3.46 ; PFAM: PF00300 PF01591 ; SCOP: 31961 34003
DBALI1bifA 
CATH3.40.50.300 Domain: 1bifA01 P-loop containing nucleotide triphosphate hydrolases (100%)
CATH3.40.50.1240 Domain: 1bifA02 Phosphoglycerate mutase-like (100%)
JenaImageLibrary1bif 
Target Sequence
UniProtKBQ5S3G5RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;Short=6PF-2-K/Fru-2,6-P2ase 4;Short=PFK/FBPase 4;AltName: Full=6PF-2-K/Fru-2,6-P2ase testis-type isozyme;Includes:RecName: Full=6-p
InterProQ5S3G5 
PFAMQ5S3G5 
ProdomQ5S3G5 
UniProtKBH2QMJ4SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 {ECO:0000313|EMBL:JAA01300.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000025688};
InterProH2QMJ4 
PFAMH2QMJ4 
ProdomH2QMJ4 
UniProtKBQ16877RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;Short=6PF-2-K/Fru-2,6-P2ase 4;Short=PFK/FBPase 4;AltName: Full=6PF-2-K/Fru-2,6-P2ase testis-type isozyme;Includes:RecName: Full=6-p
InterProQ16877 
PFAMQ16877 
ProdomQ16877 
UniProtKBA0A2J8P9X26-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2J8P9X2 
PFAMA0A2J8P9X2 
ProdomA0A2J8P9X2 
UniProtKBA0A2R9C0V96-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2R9C0V9 
PFAMA0A2R9C0V9 
ProdomA0A2R9C0V9 
UniProtKBA0A6D2VU346-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A6D2VU34 
PFAMA0A6D2VU34 
ProdomA0A6D2VU34 
UniProtKBH2QMJ4SubName: Full=Uncharacterized protein;
InterProH2QMJ4 
PFAMH2QMJ4 
ProdomH2QMJ4 
UniProtKBQ5S3G5SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4;SubName: Full=Testis PFKFB4;
InterProQ5S3G5 
PFAMQ5S3G5 
ProdomQ5S3G5 
UniProtKBQ16877RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;Short=6PF-2-K/Fru-2,6-P2ase 4;Short=PFK/FBPase 4;AltName: Full=6PF-2-K/Fru-2,6-P2ase testis-type isozyme;Includes:RecName: Full=6-p
InterProQ16877 
PFAMQ16877 
ProdomQ16877 
UniProtKBQ16877.6F264_HUMAN RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4; Short=6PF-2-K/Fru-2,6-P2ase 4; Short=PFK/FBPase 4; AltName: Full=6PF-2-K/Fru-2,6-P2ase testis-type isozyme; Includes: Re
InterProQ16877.6 
PFAMQ16877.6 
ProdomQ16877.6 
UniProtKBQ5S3G5RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;Short=6PF-2-K/Fru-2,6-P2ase 4;Short=PFK/FBPase 4;AltName: Full=6PF-2-K/Fru-2,6-P2ase testis-type isozyme;Includes:RecName: Full=6-p
InterProQ5S3G5 
PFAMQ5S3G5 
ProdomQ5S3G5 
UniProtKBQ5XLC2RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;Short=6PF-2-K/Fru-2,6-P2ase 4;Short=PFK/FBPase 4;AltName: Full=6PF-2-K/Fru-2,6-P2ase testis-type isozyme;Includes:RecName: Full=6-p
InterProQ5XLC2 
PFAMQ5XLC2 
ProdomQ5XLC2 
UniProtKBQ64EX5RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;Short=6PF-2-K/Fru-2,6-P2ase 4;Short=PFK/FBPase 4;AltName: Full=6PF-2-K/Fru-2,6-P2ase testis-type isozyme;Includes:RecName: Full=6-p
InterProQ64EX5 
PFAMQ64EX5 
ProdomQ64EX5 
RefSeqNP_004558.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Homo sapiens]
RefSeqXP_001158394.1 PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 isoform 8 [Pan troglodytes]
GenPept11449812 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Homo sapiens]
GenPept6226609F264_HUMAN RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4; Short=6PF-2-K/Fru-2,6-P2ase 4; Short=PFK/FBPase 4; AltName: Full=6PF-2-K/Fru-2,6-P2ase testis-type isozyme; Includes: Re
GenPept213506109unnamed protein product
GenPept207100669unnamed protein product
GenPept19057616-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase
GenPept163074446-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
GenPept14736265 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Homo sapiens]
GenPept1239962996-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, partial
GenPept1195852946-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
GenPept114586691 PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 8 [Pan troglodytes]
GenPept311643968unnamed protein product
GenPept4165894testis 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase
GenPept4758902 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Homo sapiens]
GenPept592999537Sequence 470 from patent US 8647822
GenPept55793506testis PFKFB4
GenBankAAH10269.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Homo sapiens]
GenBankAAV65753.1 testis PFKFB4 [Homo sapiens]
GenBankABM85751.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [synthetic construct]
GenBankEAW64890.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Homo sapiens]
GenBankAAD09427.1 testis 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase [Homo sapiens]
ENSEMBLENSP000002323756-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (6PF-2-K/Fru- 2,6-P2ASE testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]. [Homo
ENSEMBLENSP00000232375 
ENSEMBLENSP00000232375TDI sequence
ENSEMBLENSP00000232375 
UCSCGenomeBrowserQ16877