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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P05187
Original Database ID EN ENSP00000375881.2
Organism Homo sapiens
Annotation recname: full=alkaline phosphatase,
placental type;ec=3.1.3.1;altname:
full=alka line phosphatase regan
isozyme;altname: full=placental
alkaline phosp ...
Sequence Length 535
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs1130335 P25 PL   X
rs13026692 I89 IL  
rs17412756 N106 NS  
rs1048988 R231 RP  
rs12617638 R263 RH  
rs17838624 R263 RH   X
rs2853378 R263 RH  
rs1048991 M276 ML   *
rs1048992 R319 RL   * X
rs1048994 E451 EG  
13 SNPs found but only 10 displayed. View all SNPs for this sequence.
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1zedalkaline phosphatase from human placenta in complex with p-nitrophenyl-phosphonate
DBALI1zedA 
CATH3.40.720.10 Domain: 1zedA00 Alkaline Phosphatase, subunit A (100%)
JenaImageLibrary1zed 
Target Sequence
UniProtKBQ96DB7RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProQ96DB7 
PFAMQ96DB7 
ProdomQ96DB7 
UniProtKBP05187RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProP05187 
PFAMP05187 
ProdomP05187 
UniProtKBP05188RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProP05188 
PFAMP05188 
ProdomP05188 
UniProtKBP06861RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProP06861 
PFAMP06861 
ProdomP06861 
UniProtKBQ53S78RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProQ53S78 
PFAMQ53S78 
ProdomQ53S78 
UniProtKBQ53S78Hypothetical protein ALPP (Placental alkaline phosphatase,)
InterProQ53S78 
PFAMQ53S78 
ProdomQ53S78 
UniProtKBP05187RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProP05187 
PFAMP05187 
ProdomP05187 
UniProtKBQ96DB7RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProQ96DB7 
PFAMQ96DB7 
ProdomQ96DB7 
UniProtKBP05187.2PPB1_HUMAN RecName: Full=Alkaline phosphatase, placental type; AltName: Full=Alkaline phosphatase Regan isozyme; AltName: Full=Placental alkaline phosphatase 1; Short=PLAP-1; Flags: Precursor
InterProP05187.2 
PFAMP05187.2 
ProdomP05187.2 
UniProtKBP05188RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProP05188 
PFAMP05188 
ProdomP05188 
UniProtKBP06861RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProP06861 
PFAMP06861 
ProdomP06861 
UniProtKBQ53S78RecName: Full=Alkaline phosphatase, placental type;EC=3.1.3.1;AltName: Full=Alkaline phosphatase Regan isozyme;AltName: Full=Placental alkaline phosphatase 1;Short=PLAP-1;Flags: Precursor;
InterProQ53S78 
PFAMQ53S78 
ProdomQ53S78 
RefSeqNP_001623.3 alkaline phosphatase, placental type preproprotein [Homo sapiens]
GenPept1070483PAHUA alkaline phosphatase (EC 3.1.3.1) precursor, placental - human
GenPept62988700unknown
GenPept130737PPB1_HUMAN RecName: Full=Alkaline phosphatase, placental type; AltName: Full=Alkaline phosphatase Regan isozyme; AltName: Full=Placental alkaline phosphatase 1; Short=PLAP-1; Flags: Precursor
GenPept16157393 (XM_044131) placental alkaline phosphatase precursor [Homo sapiens]
GenPept178476placental alkaline phosphatase-1
GenPept94721246 alkaline phosphatase, placental type preproprotein [Homo sapiens]
GenPept756923015Sequence 113 from patent US 8859256
GenPept63100304Alkaline phosphatase, placental (Regan isozyme)
GenPept261385134unnamed protein product
GenPept46250429Alkaline phosphatase, placental (Regan isozyme)
GenBankAAY24087.1 unknown [Homo sapiens]
GenBankAAA51710.1 placental alkaline phosphatase-1 [Homo sapiens]
GenBankAAH68501.1 Alkaline phosphatase, placental (Regan isozyme) [Homo sapiens]
GenBankAAH94743.1 Alkaline phosphatase, placental (Regan isozyme) [Homo sapiens]
ENSEMBLENSP00000295450Alkaline phosphatase, placental type precursor (EC 3.1.3.1) (PLAP-1) (Regan isozyme). [Homo sapiens]
ENSEMBLENSP00000295450 
ENSEMBLENSP00000295450TDI sequence
ENSEMBLGENSCAN00000034293 
ENSEMBLENSP00000375881 
UCSCGenomeBrowserP05187