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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link O95348
Original Database ID EN ENSP00000330237.5
Organism Homo sapiens, synthetic construct
Annotation recname: full=caspase-9;short=casp-9;ec=3.4.22.62;altname:
full=apoptotic protea se mch-6;altname:
full=apoptotic protease-activating
factor 3;short=a ...
Sequence Length 416
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs1052576 Q221 QR   X
rs1052574 L197 LP  
rs2308939 R192 RSGC   X
rs9282624 I185 IM   X
rs2308949 G176 GR   X
rs2308950 R173 RH   X
12 SNPs found but only 6 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1nw9structure of caspase-9 in an inhibitory complex with xiap-bir3 ; PFAM: PF00653 PF00656
DBALI1nw9B 
CATH3.40.50.1460 Domain: 1nw9B00 Rossmann fold (100%)
JenaImageLibrary1nw9 
Target Sequence
UniProtKBQ9UEQ3RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProQ9UEQ3 
PFAMQ9UEQ3 
ProdomQ9UEQ3 
UniProtKBQ9UIJ8RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProQ9UIJ8 
PFAMQ9UIJ8 
ProdomQ9UIJ8 
UniProtKBQ9BQ62Caspase 9, apoptosis-related cysteine protease (BA265F14.4) (caspaseDE 9, apoptosis-related cysteine protease (MCH6))
InterProQ9BQ62 
PFAMQ9BQ62 
ProdomQ9BQ62 
UniProtKBQ53Y70SubName: Full=Caspase 9, apoptosis-related cysteine protease;SubName: Full=Caspase 9, apoptosis-related cysteine peptidase, isoform CRA_a;
InterProQ53Y70 
PFAMQ53Y70 
ProdomQ53Y70 
UniProtKBP55211.3CASP9_HUMAN RecName: Full=Caspase-9; Short=CASP-9; AltName: Full=Apoptotic protease Mch-6; AltName: Full=Apoptotic protease-activating factor 3; Short=APAF-3; AltName: Full=ICE-like apoptotic protease
InterProP55211.3 
PFAMP55211.3 
ProdomP55211.3 
UniProtKBO95348RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProO95348 
PFAMO95348 
ProdomO95348 
UniProtKBP55211RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProP55211 
PFAMP55211 
ProdomP55211 
UniProtKBQ53Y70RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProQ53Y70 
PFAMQ53Y70 
ProdomQ53Y70 
UniProtKBQ5JRU9RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProQ5JRU9 
PFAMQ5JRU9 
ProdomQ5JRU9 
UniProtKBQ92852RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProQ92852 
PFAMQ92852 
ProdomQ92852 
UniProtKBQ9BQ62RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProQ9BQ62 
PFAMQ9BQ62 
ProdomQ9BQ62 
UniProtKBQ9UEQ3RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProQ9UEQ3 
PFAMQ9UEQ3 
ProdomQ9UEQ3 
UniProtKBQ9UIJ8RecName: Full=Caspase-9;Short=CASP-9;EC=3.4.22.62;AltName: Full=Apoptotic protease Mch-6;AltName: Full=Apoptotic protease-activating factor 3;Short=APAF-3;AltName: Full=ICE-like apoptotic protease 6;S
InterProQ9UIJ8 
PFAMQ9UIJ8 
ProdomQ9UIJ8 
RefSeqNP_001220.2 caspase-9 isoform alpha preproprotein [Homo sapiens]
GenPept14744000 caspase 9, isoform beta preproprotein [Homo sapiens]
GenPept757280399Sequence 351 from patent US 8663633
GenPept649098922CASP9, partial
GenPept60656071caspase 9
GenPept307684510caspase 9, apoptosis-related cysteine peptidase, partial
GenPept30582661caspase 9, apoptosis-related cysteine protease
GenPept28558771CASP9_HUMAN RecName: Full=Caspase-9; Short=CASP-9; AltName: Full=Apoptotic protease Mch-6; AltName: Full=Apoptotic protease-activating factor 3; Short=APAF-3; AltName: Full=ICE-like apoptotic protease
GenPept14790124 caspase-9 isoform alpha preproprotein [Homo sapiens]
GenPept14744006 caspase 9, isoform alpha preproprotein [Homo sapiens]
GenPept14744002 caspase 9, apoptosis-related cysteine protease [Homo sapiens]
GenPept14530778caspase 9, apoptosis-related cysteine peptidase
GenPept13623673Caspase 9, apoptosis-related cysteine peptidase
GenPept12803273Caspase 9, apoptosis-related cysteine peptidase
GenPept123981580caspase 9, apoptosis-related cysteine peptidase
GenPept312150460caspase 9, apoptosis-related cysteine peptidase, partial
GenPept397146721Sequence 351 from patent US 8211428
GenPept60656069caspase 9
GenPept544090409Sequence 68 from patent US 8530168
GenPept119572115caspase 9, apoptosis-related cysteine peptidase, isoform CRA_a
GenBankABM82619.1 caspase 9, apoptosis-related cysteine peptidase [synthetic construct]
GenBankAAX32599.1 caspase 9 [synthetic construct]
GenBankAAP35557.1 caspase 9, apoptosis-related cysteine protease [Homo sapiens]
GenBankEAW51730.1 caspase 9, apoptosis-related cysteine peptidase, isoform CRA_a [Homo sapiens]
GenBankAAH06463.1 Caspase 9, apoptosis-related cysteine peptidase [Homo sapiens]
GenBankAAH02452.1 Caspase 9, apoptosis-related cysteine peptidase [Homo sapiens]
GenBankAAX32598.1 caspase 9 [synthetic construct]
ENSEMBLENSP00000330237Caspase-9 precursor (EC 3.4.22.-) (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6) (Apoptotic protease Mch-6) (Apoptotic protease activating factor 3) (APAF-3). [Homo sapiens]
EMBLCAC42423.1 
ENSEMBLENSP00000330237 
ENSEMBLENSP00000330237TDI sequence
ENSEMBLENSP00000330237 
UCSCGenomeBrowserP55211