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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link A0A024RBX9
Original Database ID EN ENSP00000394382.2
Organism Callithrix jacchus, Cebus apella, etc.
Annotation recname: full=pyruvate dehydrogenase
e1 component subunit alpha {eco:0000256|rul
ebase:ru361139};ec=1.2.4.1 {eco:0000256|rulebase:ru361139};
Sequence Length 390
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs11554111 H113 HY  
rs28935188 L216 LF   *
rs28935186 Y242 YN  
rs28936081 R263 RG  
rs3810710 M282 ML   X
rs28935187 D315 DN   *
rs2228067 E333 ED  

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3exicrystal structure of the pyruvate dehydrogenase (e1p) component of human pyruvate dehydrogenase complex with the subunit-binding domain (sbd) of e2p, but sbd cannot be modeled into the electron densit
DBALI3exiA 
JenaImageLibrary3exi 
Target Sequence
UniProtKBG3RCK8RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139};EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139};
InterProG3RCK8 
PFAMG3RCK8 
ProdomG3RCK8 
UniProtKBF7HBM4RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139};EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139};
InterProF7HBM4 
PFAMF7HBM4 
ProdomF7HBM4 
UniProtKBQ9UBU0RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ9UBU0 
PFAMQ9UBU0 
ProdomQ9UBU0 
UniProtKBG1RFJ2RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139};EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139};
InterProG1RFJ2 
PFAMG1RFJ2 
ProdomG1RFJ2 
UniProtKBQ9UNG4RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ9UNG4 
PFAMQ9UNG4 
ProdomQ9UNG4 
UniProtKBQ9UNG5RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ9UNG5 
PFAMQ9UNG5 
ProdomQ9UNG5 
UniProtKBA0A024RBX9RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139};EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139};
InterProA0A024RBX9 
PFAMA0A024RBX9 
ProdomA0A024RBX9 
UniProtKBH2QYD5RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139};EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139};
InterProH2QYD5 
PFAMH2QYD5 
ProdomH2QYD5 
UniProtKBF7H490RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139};EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139};
InterProF7H490 
PFAMF7H490 
ProdomF7H490 
UniProtKBG3RCK8SubName: Full=Uncharacterized protein;
InterProG3RCK8 
PFAMG3RCK8 
ProdomG3RCK8 
UniProtKBF7HBM4SubName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform 1;SubName: Full=Uncharacterized protein;
InterProF7HBM4 
PFAMF7HBM4 
ProdomF7HBM4 
UniProtKBF7H490SubName: Full=Uncharacterized protein;
InterProF7H490 
PFAMF7H490 
ProdomF7H490 
UniProtKBA0A6J3III1Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139}EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139}
InterProA0A6J3III1 
PFAMA0A6J3III1 
ProdomA0A6J3III1 
UniProtKBA0A6D2WWB4Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139}EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139}
InterProA0A6D2WWB4 
PFAMA0A6D2WWB4 
ProdomA0A6D2WWB4 
UniProtKBA0A2K5PQV9Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139}EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139}
InterProA0A2K5PQV9 
PFAMA0A2K5PQV9 
ProdomA0A2K5PQV9 
UniProtKBA0A2K5P3B4Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139}EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139}
InterProA0A2K5P3B4 
PFAMA0A2K5P3B4 
ProdomA0A2K5P3B4 
UniProtKBA0A2J8W447Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139}EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139}
InterProA0A2J8W447 
PFAMA0A2J8W447 
ProdomA0A2J8W447 
UniProtKBA0A2I2Y5G2Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139}EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139}
InterProA0A2I2Y5G2 
PFAMA0A2I2Y5G2 
ProdomA0A2I2Y5G2 
UniProtKBA0A2J8IZ93Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139}EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139}
InterProA0A2J8IZ93 
PFAMA0A2J8IZ93 
ProdomA0A2J8IZ93 
UniProtKBH2PV27SubName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;
InterProH2PV27 
PFAMH2PV27 
ProdomH2PV27 
UniProtKBH2QYD5SubName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;
InterProH2QYD5 
PFAMH2QYD5 
ProdomH2QYD5 
UniProtKBU3FGT0Pyruvate dehydrogenase E1 component subunit alpha {ECO:0000256|RuleBase:RU361139}EC=1.2.4.1 {ECO:0000256|RuleBase:RU361139}
InterProU3FGT0 
PFAMU3FGT0 
ProdomU3FGT0 
UniProtKBQ5JPT8SubName: Full=Pyruvate dehydrogenase (Lipoamide) alpha 1;SubName: Full=Pyruvate dehydrogenase (Lipoamide) alpha 1, isoform CRA_a;
InterProQ5JPT8 
PFAMQ5JPT8 
ProdomQ5JPT8 
UniProtKBQ9UNG5RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ9UNG5 
PFAMQ9UNG5 
ProdomQ9UNG5 
UniProtKBQ9UNG4RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ9UNG4 
PFAMQ9UNG4 
ProdomQ9UNG4 
UniProtKBQ9UBU0RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ9UBU0 
PFAMQ9UBU0 
ProdomQ9UBU0 
UniProtKBQ9UBJ8RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ9UBJ8 
PFAMQ9UBJ8 
ProdomQ9UBJ8 
UniProtKBQ9NP12RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ9NP12 
PFAMQ9NP12 
ProdomQ9NP12 
UniProtKBQ5JPT8RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ5JPT8 
PFAMQ5JPT8 
ProdomQ5JPT8 
UniProtKBQ53H41RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProQ53H41 
PFAMQ53H41 
ProdomQ53H41 
UniProtKBP08559.3ODPA_HUMAN RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; AltName: Full=PDHE1-A type I; Flags: Precursor
InterProP08559.3 
PFAMP08559.3 
ProdomP08559.3 
UniProtKBP08559RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type I;Flags: Precursor;
InterProP08559 
PFAMP08559 
ProdomP08559 
RefSeqNP_000275.1 pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform 1 precursor [Homo sapiens]
RefSeqXP_003819601.1pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
RefSeqXP_011781591.1PREDICTED: pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
GenPept14762225 pyruvate dehydrogenase (lipoamide) alpha 1 [Homo sapiens]
GenPept119619367pyruvate dehydrogenase (lipoamide) alpha 1, isoform CRA_a
GenPept219982pyruvate dehydrogenase alpha subunit
GenPept292413pyruvate dehydrogenase E1-alpha subunit
GenPept353306103Sequence 68 from patent US 8039587
GenPept35379unnamed protein product
GenPept358782496Sequence 68 from patent US 8062891
GenPept380813630pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform 1 precursor
GenPept383419059pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform 1 precursor
GenPept384947596pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform 1 precursor
GenPept387009pyruvate dehydrogenase E1-alpha subunit
GenPept190762pyruvate dehydrogenase alpha subunit precursor (EC 1.2.4.1)
GenPept189738pyruvate dehydrogenase alpha subunit
GenPept123981924pyruvate dehydrogenase (lipoamide) alpha 1
GenPept123996757pyruvate dehydrogenase (lipoamide) alpha 1, partial
GenPept123996763pyruvate dehydrogenase (lipoamide) alpha 1, partial
GenPept12803199Pyruvate dehydrogenase (lipoamide) alpha 1
GenPept129063ODPA_HUMAN RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; AltName: Full=PDHE1-A type I; Flags: Precursor
GenPept14762191 pyruvate dehydrogenase (lipoamide) alpha 1 [Homo sapiens]
GenPept14762207 pyruvate dehydrogenase (lipoamide) alpha 1 [Homo sapiens]
GenPept14762211 pyruvate dehydrogenase (lipoamide) alpha 1 [Homo sapiens]
GenPept119619366pyruvate dehydrogenase (lipoamide) alpha 1, isoform CRA_a
GenPept42683589Sequence 5 from patent US 6677144
GenPept4505685 pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform 1 precursor [Homo sapiens]
GenPept549828337Sequence 68 from patent US 8541550
GenPept56577252Sequence 36 from patent US 6773917
GenPept568533841Sequence 19606 from patent US 8586006
GenPept57209621pyruvate dehydrogenase (lipoamide) alpha 1
GenPept649102011PDHA1, partial
GenPept66034DEHUPA pyruvate dehydrogenase (lipoamide) (EC 1.2.4.1) alpha chain precursor - human
GenPept35381unnamed protein product
GenPept534490753Sequence 68 from patent US 8507277
GenPept516171713Sequence 68 from patent US 8470972
GenBankAAA60050.1 pyruvate dehydrogenase alpha subunit [Homo sapiens]
GenBankAAA60051.1 pyruvate dehydrogenase E1-alpha subunit [Homo sapiens]
GenBankAAA60227.1 pyruvate dehydrogenase E1-alpha subunit [Homo sapiens]
GenBankAAH02406.1 Pyruvate dehydrogenase (lipoamide) alpha 1 [Homo sapiens]
GenBankABM82791.1 pyruvate dehydrogenase (lipoamide) alpha 1 [synthetic construct]
GenBankEAW98961.1 pyruvate dehydrogenase (lipoamide) alpha 1, isoform CRA_a [Homo sapiens]
GenBankEAW98960.1 pyruvate dehydrogenase (lipoamide) alpha 1, isoform CRA_a [Homo sapiens]
GenBankAAA36533.1 pyruvate dehydrogenase alpha subunit precursor (EC 1.2.4.1) [Homo sapiens]
GenBankABM85983.1 pyruvate dehydrogenase (lipoamide) alpha 1 [synthetic construct]
GenBankABM85980.1 pyruvate dehydrogenase (lipoamide) alpha 1 [synthetic construct]
ENSEMBLENSP00000254142Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type I). [Homo sapiens]
EMBLCAA36934.1 
EMBLCAA36933.1 
EMBLCAI41291.1 
UCSCGenomeBrowserP08559 
UCSCGenomeBrowserENSPTRT00000040292.1 
ENSEMBLENSP00000254142 
ENSEMBLENSPTRP00000037227 
ENSEMBLENSP00000254142TDI sequence
ENSEMBLENSP00000394382