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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link P42575
Original Database ID gi 537292
Organism Homo sapiens
Annotation caspase-2 precursor (ec 3.4.22.-)
(casp-2) (ich-1 protease) (ich-de
1l/1s) [co ntains: caspase-2
subunit p18; caspase-2 subunit
p13;de caspase-2 s ...
Sequence Length 435

Dataset Information:

The newest dataset for this sequence was created on 2006-06-16. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region143-431
Protein Length435
Template PDB Code2fp3A
Template Region157-446
Sequence Identity22%
E-Value4e-41
GA3410.99
Datasetsnp-human4
ModPipe VersionModPipe1.0
Model Date2006-06-16

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB2fp3crystal structure of the drosophila initiator caspase dronc
DBALI2fp3A 
JenaImageLibrary2fp3 
Target Sequence
UniProtKBP42575Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (ICH-DE 1L/1S) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13;DE Caspase-2 subunit p12]
InterProP42575 
PFAMP42575 
ProdomP42575 
GenPept59719981Sequence 97 from patent US 6833248
GenPept537292ICH-1L
GenPept40091895Sequence 9 from patent US 6610541
GenPept34601693Sequence 9 from patent US 6376226
GenPept30172705unknown
GenPept29713371Sequence 9 from patent US 6512104
GenPept27978962caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2)
GenPept23316755Sequence 2 from patent US 6416753
GenPept1170473ICE2_HUMAN CASPASE-2 PRECURSOR (CASP-2) (ICH-1 PROTEASE) (ICH-1L/1S)
GenPept12813573Sequence 53 from patent US 6083735
GenPept12815928Sequence 51 from patent US 6087160
GenPept14741608 caspase 2, isoform 4 [Homo sapiens]
GenPept14741614 caspase 2, isoform 1 preproprotein [Homo sapiens]
GenPept21509073Sequence 9 from patent US 6379950
GenPept1082225A54821 apoptosis regulator ICH-1, stimulatory form L - human
GenBankAAA58959.1 ICH-1L [Homo sapiens]
GenBankAAO25653.1 caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2) [Homo sapiens]
GenBankAAP22346.1 unknown [Homo sapiens]
UCSCGenomeBrowserP42575