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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link A0A024RDA0
Original Database ID EN ENSP00000288135.5
Organism Homo sapiens
Annotation recname: full=receptor protein-tyrosine
kinase {eco:0000256|saas:saas00021284};e
c=2.7.10.1 {eco:0000256|saas:saas00021284};
Sequence Length 976
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs28933968 K550 KI  
rs28933371 F584 FC  
rs28933969 D816 DH  
4 SNPs found but only 3 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3g0ekit kinase domain in complex with sunitinib
DBALI3g0eA 
CATH3.30.200.20 Domain: 3g0eA01 Phosphorylase Kinase; domain 1 (98%)
CATH1.10.510.10 Domain: 3g0eA02 Transferase(Phosphotransferase) domain 1 (100%)
JenaImageLibrary3g0e 
Target Sequence
UniProtKBQ9UM99RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProQ9UM99 
PFAMQ9UM99 
ProdomQ9UM99 
UniProtKBQ99662RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProQ99662 
PFAMQ99662 
ProdomQ99662 
UniProtKBA0A024RDA0RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00021284};EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00021284};
InterProA0A024RDA0 
PFAMA0A024RDA0 
ProdomA0A024RDA0 
UniProtKBQ6IQ28RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProQ6IQ28 
PFAMQ6IQ28 
ProdomQ6IQ28 
UniProtKBD5M931RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProD5M931 
PFAMD5M931 
ProdomD5M931 
UniProtKBB5A956RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProB5A956 
PFAMB5A956 
ProdomB5A956 
UniProtKBF5H8F8RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProF5H8F8 
PFAMF5H8F8 
ProdomF5H8F8 
UniProtKBP10721RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProP10721 
PFAMP10721 
ProdomP10721 
UniProtKBD5LXN2RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProD5LXN2 
PFAMD5LXN2 
ProdomD5LXN2 
UniProtKBD5M931RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProD5M931 
PFAMD5M931 
ProdomD5M931 
UniProtKBD5LXN2RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProD5LXN2 
PFAMD5LXN2 
ProdomD5LXN2 
UniProtKBB5A956RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProB5A956 
PFAMB5A956 
ProdomB5A956 
UniProtKBQ9UM99RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProQ9UM99 
PFAMQ9UM99 
ProdomQ9UM99 
UniProtKBF5H8F8RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProF5H8F8 
PFAMF5H8F8 
ProdomF5H8F8 
UniProtKBQ99662RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProQ99662 
PFAMQ99662 
ProdomQ99662 
UniProtKBQ6IQ28RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProQ6IQ28 
PFAMQ6IQ28 
ProdomQ6IQ28 
UniProtKBP10721.1KIT_HUMAN RecName: Full=Mast/stem cell growth factor receptor; Short=SCFR; AltName: Full=Proto-oncogene c-Kit; AltName: Full=Tyrosine-protein kinase Kit; AltName: CD_antigen=CD117; Flags: Precursor
InterProP10721.1 
PFAMP10721.1 
ProdomP10721.1 
UniProtKBP10721RecName: Full=Mast/stem cell growth factor receptor Kit;Short=SCFR;EC=2.7.10.1;AltName: Full=Piebald trait protein;Short=PBT;AltName: Full=Proto-oncogene c-Kit;AltName: Full=Tyrosine-protein kinase Ki
InterProP10721 
PFAMP10721 
ProdomP10721 
RefSeqNP_000213.1 mast/stem cell growth factor receptor isoform 1 precursor [Homo sapiens]
GenPept568535984Sequence 26474 from patent US 8586006
GenPept66811TVHUKT protein-tyrosine kinase (EC 2.7.1.112), receptor type kit precursor - human
GenPept70665895unnamed protein product
GenPept756362070Sequence 3 from patent US 8697709
GenPept756446267Sequence 1 from patent US 8722702
GenPept756656064Sequence 10 from patent US 8791112
GenPept825686mast/stem cell growth factor receptor
GenPept182897728Sequence 31 from patent US 7329495
GenPept550885035Sequence 8 from patent US 8557573
GenPept520710046Sequence 1 from patent US 8461169
GenPept303216303Sequence 1 from patent US 7727731
GenPept303076460Sequence 1 from patent US 7700610
GenPept294588665Sequence 2423 from patent US 7691569
GenPept294574686Sequence 1 from patent US 7678805
GenPept228209901Sequence 1 from patent US 7498342
GenPept218055949unnamed protein product
GenPept1817733KIT protein
GenPept162493198Sequence 1 from patent US 7303893
GenPept145582017unnamed protein product
GenPept125994439unnamed protein product
GenPept125472KIT_HUMAN RecName: Full=Mast/stem cell growth factor receptor Kit; Short=SCFR; AltName: Full=Piebald trait protein; Short=PBT; AltName: Full=Proto-oncogene c-Kit; AltName: Full=Tyrosine-protein kinase
GenPept119625866v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, isoform CRA_a
GenPept119625865v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, isoform CRA_a
GenPept314138444Sequence 1 from patent US 7741335
GenPept314536184Sequence 115 from patent US 7807392
GenPept314895646Sequence 1 from patent US 7846941
GenPept478676196Sequence 1 from patent US 8404700
GenPept4557695 mast/stem cell growth factor receptor isoform 1 precursor [Homo sapiens]
GenPept402640841Sequence 2 from patent US 8247419
GenPept34085unnamed protein product
GenPept336050972Sequence 1 from patent US 7947708
GenPept331588947Sequence 4 from patent US 7910315
GenPept331495463Sequence 46 from patent US 7901881
GenPept331468550Sequence 1 from patent US 7893075
GenPept331467122Sequence 2423 from patent US 7892745
GenPept331402012Sequence 2423 from patent US 7879556
GenBankAAC50968.1 KIT protein [Homo sapiens]
GenBankEAX05461.1 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, isoform CRA_a [Homo sapiens]
GenBankEAX05460.1 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, isoform CRA_a [Homo sapiens]
ENSEMBLENSP00000288135Mast/stem cell growth factor receptor precursor (EC 2.7.1.112) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen). [Homo sapiens]
EMBLCAA29548.1 
EMBLCAA49159.1 
ENSEMBLENSP00000288135 
ENSEMBLENSP00000288135TDI sequence
ENSEMBLENSP00000288135 
UCSCGenomeBrowserP10721