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Sequence Information

Primary Database Link D3DN89
Original Database ID sp P49841
Organism Callithrix jacchus, Cebus apella, etc.
Annotation recname: full=glycogen synthase
kinase-3 beta;short=gsk-3 beta;ec=2.7.11.26;altn
ame: full=serine/threonine-protein
kinase gsk3b;ec=2.7.11.1;
Sequence Length 420

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region35-388
Protein Length420
Template PDB Code1j1bA
Template Region35-388
Sequence Identity100%
E-Value0
GA3411
MPQS2.00396
z-DOPE-1.25
TSVMod MethodMTALL
TSVMod RMSD1.031
TSVMod NO350.966
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
PharmGKB   PharmGKB data available for GSK3B
Template Structure
PDB1j1bbinary complex structure of human tau protein kinase i with amppnp
DBALI1j1bA 
CATH3.30.200.20 Domain: 1j1bA01 Phosphorylase Kinase; domain 1 (100%)
CATH1.10.510.10 Domain: 1j1bA02 Transferase(Phosphotransferase) domain 1 (100%)
JenaImageLibrary1j1b 
Target Sequence
UniProtKBQ9BWH3RecName: Full=Glycogen synthase kinase-3 beta;Short=GSK-3 beta;EC=2.7.11.26;AltName: Full=Serine/threonine-protein kinase GSK3B;EC=2.7.11.1;
InterProQ9BWH3 
PFAMQ9BWH3 
ProdomQ9BWH3 
UniProtKBP49841RecName: Full=Glycogen synthase kinase-3 beta;Short=GSK-3 beta;EC=2.7.11.26;AltName: Full=Serine/threonine-protein kinase GSK3B;EC=2.7.11.1;
InterProP49841 
PFAMP49841 
ProdomP49841 
UniProtKBK7CFX8SubName: Full=Glycogen synthase kinase 3 beta {ECO:0000313|EMBL:JAA17817.1};
InterProK7CFX8 
PFAMK7CFX8 
ProdomK7CFX8 
UniProtKBH9EPM2SubName: Full=Glycogen synthase kinase-3 beta isoform 2 {ECO:0000313|EMBL:AFE64331.1};
InterProH9EPM2 
PFAMH9EPM2 
ProdomH9EPM2 
UniProtKBQ6FI27SubName: Full=GSK3B protein {ECO:0000313|EMBL:CAG38748.1};SubName: Full=GSK3beta isoform {ECO:0000313|EMBL:ABX89591.1};SubName: Full=Glycogen synthase kinase 3 beta, isoform CRA_b {ECO:0000313|EMBL:EA
InterProQ6FI27 
PFAMQ6FI27 
ProdomQ6FI27 
UniProtKBF6YPA3SubName: Full=Glycogen synthase kinase-3 beta isoform 2 {ECO:0000313|EMBL:JAB08288.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCJAP00000016211};
InterProF6YPA3 
PFAMF6YPA3 
ProdomF6YPA3 
UniProtKBD3DN89RecName: Full=Glycogen synthase kinase-3 beta;Short=GSK-3 beta;EC=2.7.11.26;AltName: Full=Serine/threonine-protein kinase GSK3B;EC=2.7.11.1;
InterProD3DN89 
PFAMD3DN89 
ProdomD3DN89 
UniProtKBQ9UL47RecName: Full=Glycogen synthase kinase-3 beta;Short=GSK-3 beta;EC=2.7.11.26;AltName: Full=Serine/threonine-protein kinase GSK3B;EC=2.7.11.1;
InterProQ9UL47 
PFAMQ9UL47 
ProdomQ9UL47 
UniProtKBD3DN88Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProD3DN88 
PFAMD3DN88 
ProdomD3DN88 
UniProtKBA0A2R9C6C8Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2R9C6C8 
PFAMA0A2R9C6C8 
ProdomA0A2R9C6C8 
UniProtKBA0A6D2WIC6Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A6D2WIC6 
PFAMA0A6D2WIC6 
ProdomA0A6D2WIC6 
UniProtKBA0A6J3JJ31Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A6J3JJ31 
PFAMA0A6J3JJ31 
ProdomA0A6J3JJ31 
UniProtKBA0A8D2EGN3SubName: Full=Glycogen synthase kinase 3 beta {ECO:0000313|Ensembl:ENSTGEP00000006137}
InterProA0A8D2EGN3 
PFAMA0A8D2EGN3 
ProdomA0A8D2EGN3 
UniProtKBH9EPM2SubName: Full=Glycogen synthase kinase-3 beta isoform 2;
InterProH9EPM2 
PFAMH9EPM2 
ProdomH9EPM2 
UniProtKBA0A8I5UKS7Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A8I5UKS7 
PFAMA0A8I5UKS7 
ProdomA0A8I5UKS7 
UniProtKBA0A2K5U1V1Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2K5U1V1 
PFAMA0A2K5U1V1 
ProdomA0A2K5U1V1 
UniProtKBA0A2K5U1X8Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2K5U1X8 
PFAMA0A2K5U1X8 
ProdomA0A2K5U1X8 
UniProtKBF6YPA3SubName: Full=Uncharacterized protein;
InterProF6YPA3 
PFAMF6YPA3 
ProdomF6YPA3 
UniProtKBA0A2K5Z9W2Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2K5Z9W2 
PFAMA0A2K5Z9W2 
ProdomA0A2K5Z9W2 
UniProtKBA0A2K5I3H2Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2K5I3H2 
PFAMA0A2K5I3H2 
ProdomA0A2K5I3H2 
UniProtKBA0A2J8M3L0Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2J8M3L0 
PFAMA0A2J8M3L0 
ProdomA0A2J8M3L0 
UniProtKBA0A2I3LKM7Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2I3LKM7 
PFAMA0A2I3LKM7 
ProdomA0A2I3LKM7 
UniProtKBA0A2I3GEZ5Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2I3GEZ5 
PFAMA0A2I3GEZ5 
ProdomA0A2I3GEZ5 
UniProtKBA0A2K5M9Z3Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2K5M9Z3 
PFAMA0A2K5M9Z3 
ProdomA0A2K5M9Z3 
UniProtKBA0A2R8M2M3Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2R8M2M3 
PFAMA0A2R8M2M3 
ProdomA0A2R8M2M3 
UniProtKBA0A2K5QF67Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2K5QF67 
PFAMA0A2K5QF67 
ProdomA0A2K5QF67 
UniProtKBQ6FI27SubName: Full=GSK3B protein;SubName: Full=GSK3beta isoform;SubName: Full=Glycogen synthase kinase 3 beta, isoform CRA_b;SubName: Full=cDNA FLJ75266, highly similar to Homo sapiens glycogen synthase ki
InterProQ6FI27 
PFAMQ6FI27 
ProdomQ6FI27 
UniProtKBA0A2I2Y1S1Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2I2Y1S1 
PFAMA0A2I2Y1S1 
ProdomA0A2I2Y1S1 
UniProtKBA0A2J8W250Glycogen synthase kinase-3 beta {ECO:0000256|ARBA:ARBA00015835}EC=2.7.11.26 {ECO:0000256|ARBA:ARBA00012407}
InterProA0A2J8W250 
PFAMA0A2J8W250 
ProdomA0A2J8W250 
UniProtKBD3DN89RecName: Full=Glycogen synthase kinase-3 beta;Short=GSK-3 beta;EC=2.7.11.26;AltName: Full=Serine/threonine-protein kinase GSK3B;EC=2.7.11.1;
InterProD3DN89 
PFAMD3DN89 
ProdomD3DN89 
UniProtKBQ9UL47RecName: Full=Glycogen synthase kinase-3 beta;Short=GSK-3 beta;EC=2.7.11.26;AltName: Full=Serine/threonine-protein kinase GSK3B;EC=2.7.11.1;
InterProQ9UL47 
PFAMQ9UL47 
ProdomQ9UL47 
UniProtKBQ9BWH3RecName: Full=Glycogen synthase kinase-3 beta;Short=GSK-3 beta;EC=2.7.11.26;AltName: Full=Serine/threonine-protein kinase GSK3B;EC=2.7.11.1;
InterProQ9BWH3 
PFAMQ9BWH3 
ProdomQ9BWH3 
UniProtKBP49841.2GSK3B_HUMAN RecName: Full=Glycogen synthase kinase-3 beta; Short=GSK-3 beta
InterProP49841.2 
PFAMP49841.2 
ProdomP49841.2 
UniProtKBP49841RecName: Full=Glycogen synthase kinase-3 beta;Short=GSK-3 beta;EC=2.7.11.26;AltName: Full=Serine/threonine-protein kinase GSK3B;EC=2.7.11.1;
InterProP49841 
PFAMP49841 
ProdomP49841 
RefSeqXP_012319348.1glycogen synthase kinase-3 beta isoform X2
RefSeqXP_033067001.1glycogen synthase kinase-3 beta isoform X2
RefSeqXP_028700433.1glycogen synthase kinase-3 beta isoform X2
RefSeqXP_025231586.1glycogen synthase kinase-3 beta isoform X2
RefSeqXP_024100348.1glycogen synthase kinase-3 beta isoform X2
RefSeqXP_021788803.1glycogen synthase kinase-3 beta isoform X5
RefSeqXP_007983865.1glycogen synthase kinase-3 beta isoform X2
RefSeqXP_002758816.1 PREDICTED: glycogen synthase kinase-3 beta isoform 2 [Callithrix jacchus]
RefSeqXP_030797465.1glycogen synthase kinase-3 beta isoform X2
RefSeqXP_032005973.1glycogen synthase kinase-3 beta isoform X2
RefSeqNP_001139628.1 glycogen synthase kinase-3 beta isoform 2 [Homo sapiens]
PDB1J1BAChain A, Binary Complex Structure Of Human Tau Protein Kinase I With Amppnp
PDB3M1SBChain B, Structure Of Ruthenium Half-sandwich Complex Bound To Glycogen Synthase Kinase 3
PDB2JLDB Chain B, Extremely Tight Binding Of Ruthenium Complex To Glycogen Synthase Kinase 3
PDB3M1SAChain A, Structure Of Ruthenium Half-sandwich Complex Bound To Glycogen Synthase Kinase 3
PDB1I09BChain B, Structure Of Glycogen Synthase Kinase-3 (Gsk3b)
PDB1J1BB Chain B, Binary Complex Structure Of Human Tau Protein Kinase I With Amppnp
PDB1J1BBChain B, Binary Complex Structure Of Human Tau Protein Kinase I With Amppnp
PDB1J1CB Chain B, Binary Complex Structure Of Human Tau Protein Kinase I With Adp
PDB1J1CAChain A, Binary Complex Structure Of Human Tau Protein Kinase I With Adp
PDB1J1CBChain B, Binary Complex Structure Of Human Tau Protein Kinase I With Adp
PDB2JLDBChain B, Extremely Tight Binding Of Ruthenium Complex To Glycogen Synthase Kinase 3
PDB3PUPAChain A, Structure Of Glycogen Synthase Kinase 3 Beta (Gsk3b) In Complex With A Ruthenium Octasporine Ligand (Os1)
PDB3PUPBChain B, Structure Of Glycogen Synthase Kinase 3 Beta (Gsk3b) In Complex With A Ruthenium Octasporine Ligand (Os1)
PDB2JLDAChain A, Extremely Tight Binding Of Ruthenium Complex To Glycogen Synthase Kinase 3
PDB1I09B Chain B, Structure Of Glycogen Synthase Kinase-3 (Gsk3b)
PDB1I09AChain A, Structure Of Glycogen Synthase Kinase-3 (Gsk3b)
GenPept197002197Sequence 1 from patent US 7390808
GenPept119599941glycogen synthase kinase 3 beta, isoform CRA_b
GenPept119599940glycogen synthase kinase 3 beta, isoform CRA_b
GenPept296226174 PREDICTED: glycogen synthase kinase-3 beta isoform 2 [Callithrix jacchus]
GenPept294557245Sequence 1 from patent US 7666647
GenPept259281872Sequence 13 from patent US 7572949
GenPept217035214B Chain B, Extremely Tight Binding Of Ruthenium Complex To Glycogen Synthase Kinase 3
GenPept217035213A Chain A, Extremely Tight Binding Of Ruthenium Complex To Glycogen Synthase Kinase 3
GenPept158255230unnamed protein product
GenPept162423650GSK3beta isoform
GenPept168277850glycogen synthase kinase-3 beta, partial
GenPept18158778B Chain B, Structure Of Glycogen Synthase Kinase-3 (Gsk3b)
GenPept20455502GSK3B_HUMAN RecName: Full=Glycogen synthase kinase-3 beta; Short=GSK-3 beta
GenPept18158777A Chain A, Structure Of Glycogen Synthase Kinase-3 (Gsk3b)
GenPept384940564glycogen synthase kinase-3 beta isoform 2
GenPept383417779glycogen synthase kinase-3 beta isoform 2
GenPept508119951Sequence 5 from patent US 8445648
GenPept39644671GSK3B protein
GenPept40889054A Chain A, Binary Complex Structure Of Human Tau Protein Kinase I With Amppnp
GenPept40889055B Chain B, Binary Complex Structure Of Human Tau Protein Kinase I With Amppnp
GenPept40889056A Chain A, Binary Complex Structure Of Human Tau Protein Kinase I With Adp
GenPept40889057B Chain B, Binary Complex Structure Of Human Tau Protein Kinase I With Adp
GenPept430255668Sequence 3 from patent US 8323919
GenPept756521761Sequence 159 from patent US 8741556
GenPept380784911glycogen synthase kinase-3 beta isoform 2
GenPept331427789Sequence 1 from patent US 7883881
GenPept310935069unnamed protein product
GenPept315364449A Chain A, Structure Of Ruthenium Half-sandwich Complex Bound To Glycogen Synthase Kinase 3
GenPept49168506GSK3B
GenPept225903437 glycogen synthase kinase-3 beta isoform 2 [Homo sapiens]
GenPept508119949Sequence 1 from patent US 8445648
GenPept315364450B Chain B, Structure Of Ruthenium Half-sandwich Complex Bound To Glycogen Synthase Kinase 3
GenPept315364781A Chain A, Structure Of Glycogen Synthase Kinase 3 Beta (Gsk3b) In Complex With A Ruthenium Octasporine Ligand (Os1)
GenPept315364782B Chain B, Structure Of Glycogen Synthase Kinase 3 Beta (Gsk3b) In Complex With A Ruthenium Octasporine Ligand (Os1)
GenPept430157264Sequence 1 from patent US 8318467
GenBankEAW79534.1 glycogen synthase kinase 3 beta, isoform CRA_b [Homo sapiens]
GenBankEAW79535.1 glycogen synthase kinase 3 beta, isoform CRA_b [Homo sapiens]
GenBankAAH12760.1 GSK3B protein [Homo sapiens]
GenBankABX89591.1 GSK3beta isoform [Homo sapiens]
UCSCGenomeBrowserP49841 
ENSEMBLENSP00000264235 
ENSEMBLENSP00000264235TDI sequence
ENSEMBLENSP00000264235