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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P11802.2
Original Database ID CAG47043.1 CDK
Organism Gorilla gorilla gorilla, Pan paniscus, etc.
Annotation cdk4_human recname: full=cell
division protein kinase 4; altname:
full=cyclin-de pendent kinase
4; altname: full=psk-j3
Sequence Length 303
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs28365051 E263 EQK  
rs3211612 R82 RQ   * X
rs11547328 R24 RC  
4 SNPs found but only 3 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB2w9zcrystal structure of cdk4 in complex with a d-type cyclin
DBALI2w9zB 
CATH3.30.200.20 Domain: 2w9zB01 Phosphorylase Kinase; domain 1 (100%)
CATH1.10.510.10 Domain: 2w9zB02 Transferase(Phosphotransferase) domain 1 (100%)
JenaImageLibrary2w9z 
Target Sequence
UniProtKBQ6FG61RecName: Full=Cyclin-dependent kinase 4;EC=2.7.11.22;AltName: Full=Cell division protein kinase 4;AltName: Full=PSK-J3;
InterProQ6FG61 
PFAMQ6FG61 
ProdomQ6FG61 
UniProtKBG3QGD2SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000001387};
InterProG3QGD2 
PFAMG3QGD2 
ProdomG3QGD2 
UniProtKBO00576RecName: Full=Cyclin-dependent kinase 4;EC=2.7.11.22;AltName: Full=Cell division protein kinase 4;AltName: Full=PSK-J3;
InterProO00576 
PFAMO00576 
ProdomO00576 
UniProtKBH2QZZ4SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|EMBL:JAA01034.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000039845};
InterProH2QZZ4 
PFAMH2QZZ4 
ProdomH2QZZ4 
UniProtKBP11802RecName: Full=Cyclin-dependent kinase 4;EC=2.7.11.22;AltName: Full=Cell division protein kinase 4;AltName: Full=PSK-J3;
InterProP11802 
PFAMP11802 
ProdomP11802 
UniProtKBA0A024RBB6SubName: Full=Cyclin-dependent kinase 4, isoform CRA_a;
InterProA0A024RBB6 
PFAMA0A024RBB6 
ProdomA0A024RBB6 
UniProtKBA0A6D2XU49SubName: Full=CDK4 isoform 2 {ECO:0000313|EMBL:PNI39148.1}
InterProA0A6D2XU49 
PFAMA0A6D2XU49 
ProdomA0A6D2XU49 
UniProtKBA0A2R9BHC1Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2R9BHC1 
PFAMA0A2R9BHC1 
ProdomA0A2R9BHC1 
UniProtKBG3QGD2SubName: Full=Uncharacterized protein;
InterProG3QGD2 
PFAMG3QGD2 
ProdomG3QGD2 
UniProtKBH2QZZ4SubName: Full=Uncharacterized protein;
InterProH2QZZ4 
PFAMH2QZZ4 
ProdomH2QZZ4 
UniProtKBA0A2J8KVV7SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|EMBL:JAA01034.1, ECO:0000313|Ensembl:ENSPTRP00000039845}
InterProA0A2J8KVV7 
PFAMA0A2J8KVV7 
ProdomA0A2J8KVV7 
UniProtKBQ6FG61SubName: Full=CDK4 protein;SubName: Full=Cyclin-dependent kinase 4, isoform CRA_a;
InterProQ6FG61 
PFAMQ6FG61 
ProdomQ6FG61 
UniProtKBO00576RecName: Full=Cyclin-dependent kinase 4;EC=2.7.11.22;AltName: Full=Cell division protein kinase 4;AltName: Full=PSK-J3;
InterProO00576 
PFAMO00576 
ProdomO00576 
UniProtKBQ6FG61RecName: Full=Cyclin-dependent kinase 4;EC=2.7.11.22;AltName: Full=Cell division protein kinase 4;AltName: Full=PSK-J3;
InterProQ6FG61 
PFAMQ6FG61 
ProdomQ6FG61 
UniProtKBP11802RecName: Full=Cyclin-dependent kinase 4;EC=2.7.11.22;AltName: Full=Cell division protein kinase 4;AltName: Full=PSK-J3;
InterProP11802 
PFAMP11802 
ProdomP11802 
UniProtKBB4DNF9RecName: Full=Cyclin-dependent kinase 4;EC=2.7.11.22;AltName: Full=Cell division protein kinase 4;AltName: Full=PSK-J3;
InterProB4DNF9 
PFAMB4DNF9 
ProdomB4DNF9 
UniProtKBB2R9A0RecName: Full=Cyclin-dependent kinase 4;EC=2.7.11.22;AltName: Full=Cell division protein kinase 4;AltName: Full=PSK-J3;
InterProB2R9A0 
PFAMB2R9A0 
ProdomB2R9A0 
UniProtKBP11802.2CDK4_HUMAN RecName: Full=Cell division protein kinase 4; AltName: Full=Cyclin-dependent kinase 4; AltName: Full=PSK-J3
InterProP11802.2 
PFAMP11802.2 
ProdomP11802.2 
RefSeqNP_000066.1 cell division protein kinase 4 [Homo sapiens]
RefSeqXP_509173.2 PREDICTED: cyclin-dependent kinase 4 [Pan troglodytes]
GenPept13543415Cyclin-dependent kinase 4
GenPept76000254Sequence 205 from patent US 6936450
GenPept76000253Sequence 204 from patent US 6936450
GenPept756536563Sequence 55 from patent US 8748389
GenPept756521741Sequence 139 from patent US 8741556
GenPept649150787CDK4, partial
GenPept649099090CDK4, partial
GenPept60818877cyclin-dependent kinase 4
GenPept114644117 PREDICTED: cyclin-dependent kinase 4 [Pan troglodytes]
GenPept123992922cyclin-dependent kinase 4
GenPept20514391AF507942_1 cyclin-dependent kinase 4
GenPept17986211CDK4
GenPept155076296Sequence 9 from patent US 7202033
GenPept15302315 cyclin-dependent kinase 4 [Homo sapiens]
GenPept14758371 cyclin-dependent kinase 4 [Homo sapiens]
GenPept14758361 cyclin-dependent kinase 4 [Homo sapiens]
GenPept14603406Cyclin-dependent kinase 4
GenPept1353416cyclin-dependent kinase 4
GenPept13177739Cyclin-dependent kinase 4
GenPept123999821cyclin-dependent kinase 4, partial
GenPept119617466cyclin-dependent kinase 4, isoform CRA_a
GenPept119617464cyclin-dependent kinase 4, isoform CRA_a
GenPept1168867CDK4_HUMAN RecName: Full=Cyclin-dependent kinase 4; AltName: Full=Cell division protein kinase 4; AltName: Full=PSK-J3
GenPept261859944cyclin-dependent kinase 4, partial
GenPept534486089Sequence 77 from patent US 8506948
GenPept47115273CDK4, partial
GenPept49457488CDK4
GenPept4502735 cell division protein kinase 4 [Homo sapiens]
GenPept348082869Sequence 317 from patent US 8026065
GenPept549269914unnamed protein product
GenPept568531266Sequence 12216 from patent US 8586006
GenPept583810181unnamed protein product
GenPept60817395cyclin-dependent kinase 4
GenPept456427cyclin-dependent protein kinase, type 4
GenBankAAH10153.1 Cyclin-dependent kinase 4 [Homo sapiens]
GenBankAAM23014.1AF507942_1 cyclin-dependent kinase 4 [Homo sapiens]
GenBankAAA35673.1 cyclin-dependent protein kinase, type 4 [Homo sapiens]
GenBankAAC39521.2 CDK4 [Homo sapiens]
GenBankAAX36421.1 cyclin-dependent kinase 4 [synthetic construct]
GenBankAAX36480.1 cyclin-dependent kinase 4 [synthetic construct]
GenBankABM84063.1 cyclin-dependent kinase 4 [synthetic construct]
GenBankABM87419.1 cyclin-dependent kinase 4 [synthetic construct]
GenBankAAH05864.1 Cyclin-dependent kinase 4 [Homo sapiens]
GenBankAAH03644.1 Cyclin-dependent kinase 4 [Homo sapiens]
GenBankAAC50506.1 cyclin-dependent kinase 4 [Homo sapiens]
GenBankEAW97060.1 cyclin-dependent kinase 4, isoform CRA_a [Homo sapiens]
GenBankEAW97058.1 cyclin-dependent kinase 4, isoform CRA_a [Homo sapiens]
ENSEMBLENSP00000257904Cell division protein kinase 4 (EC 2.7.1.37) (Cyclin-dependent kinase 4) (PSK-J3). [Homo sapiens]
EMBLCAG28596.1 
EMBLCAG47043.1 
UCSCGenomeBrowserP11802 
ENSEMBLENSP00000257904 
ENSEMBLENSP00000257904TDI sequence
ENSEMBLENSP00000257904