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Sequence Information

Primary Database Link A0A024R8E2
Original Database ID EN ENSP00000323315.5
Organism Homo sapiens
Annotation recname: full=tyrosine-protein
kinase {eco:0000256|rulebase:ru362096};ec=2.7.10.
2 {eco:0000256|rulebase:ru362096,
eco:0000256|saas:saas00021209};
Sequence Length 1130

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region46-511
Protein Length1130
Template PDB Code2fo0A
Template Region65-530
Sequence Identity100%
E-Value0
GA3411
MPQS1.60219
z-DOPE-1.15
TSVMod MethodMSALL
TSVMod RMSD0.988
TSVMod NO350.96
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Template Structure
PDB2fo0organization of the sh3-sh2 unit in active and inactive forms of the c-abl tyrosine kinase
DBALI2fo0A 
CATH2.30.30.40 Domain: 2fo0A01 SH3 Domains (100%)
CATH3.30.505.10 Domain: 2fo0A02 SHC Adaptor Protein (100%)
CATH3.30.200.20 Domain: 2fo0A03 Phosphorylase Kinase; domain 1 (100%)
CATH1.10.510.10 Domain: 2fo0A04 Transferase(Phosphotransferase) domain 1 (100%)
JenaImageLibrary2fo0 
Target Sequence
UniProtKBQ45F09RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ45F09 
PFAMQ45F09 
ProdomQ45F09 
UniProtKBA0A024R8E2RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096};EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096, ECO:0000256|SAAS:SAAS00021209};
InterProA0A024R8E2 
PFAMA0A024R8E2 
ProdomA0A024R8E2 
UniProtKBP00519RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProP00519 
PFAMP00519 
ProdomP00519 
UniProtKBA3KFJ3RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProA3KFJ3 
PFAMA3KFJ3 
ProdomA3KFJ3 
UniProtKBQ13869RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ13869 
PFAMQ13869 
ProdomQ13869 
UniProtKBQ13870RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ13870 
PFAMQ13870 
ProdomQ13870 
UniProtKBQ16133RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ16133 
PFAMQ16133 
ProdomQ16133 
UniProtKBQ17R61RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ17R61 
PFAMQ17R61 
ProdomQ17R61 
UniProtKBA3KFJ3SubName: Full=C-abl oncogene 1, receptor tyrosine kinase;SubName: Full=V-abl Abelson murine leukemia viral oncogene homolog 1, isoform CRA_b;
InterProA3KFJ3 
PFAMA3KFJ3 
ProdomA3KFJ3 
UniProtKBQ16133RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ16133 
PFAMQ16133 
ProdomQ16133 
UniProtKBA3KFJ3RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProA3KFJ3 
PFAMA3KFJ3 
ProdomA3KFJ3 
UniProtKBQ45F09RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ45F09 
PFAMQ45F09 
ProdomQ45F09 
UniProtKBP00519RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProP00519 
PFAMP00519 
ProdomP00519 
UniProtKBP00519.4ABL1_HUMAN RecName: Full=Tyrosine-protein kinase ABL1; AltName: Full=Abelson murine leukemia viral oncogene homolog 1; AltName: Full=Proto-oncogene c-Abl; AltName: Full=p150
InterProP00519.4 
PFAMP00519.4 
ProdomP00519.4 
UniProtKBQ17R61RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ17R61 
PFAMQ17R61 
ProdomQ17R61 
UniProtKBQ13870RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ13870 
PFAMQ13870 
ProdomQ13870 
UniProtKBQ13869RecName: Full=Tyrosine-protein kinase ABL1;EC=2.7.10.2;AltName: Full=Abelson murine leukemia viral oncogene homolog 1;AltName: Full=Abelson tyrosine-protein kinase 1;AltName: Full=Proto-oncogene c-Abl
InterProQ13869 
PFAMQ13869 
ProdomQ13869 
RefSeqNP_005148.2 tyrosine-protein kinase ABL1 isoform a [Homo sapiens]
GenPept119608354v-abl Abelson murine leukemia viral oncogene homolog 1, isoform CRA_b
GenPept568531210Sequence 12160 from patent US 8586006
GenPept15298382 hypothetical protein XP_053263 [Homo sapiens]
GenPept514267proto-oncogene tyrosine-protein kinase
GenPept14740571 v-abl Abelson murine leukemia viral oncogene homolog 1 isoform a [Homo sapiens]
GenPept62362414 tyrosine-protein kinase ABL1 isoform a [Homo sapiens]
GenPept756362078Sequence 11 from patent US 8697709
GenPept756656055Sequence 1 from patent US 8791112
GenPept757922264Sequence 2 from patent US 8603740
GenPept85681908ABL1_HUMAN RecName: Full=Tyrosine-protein kinase ABL1; AltName: Full=Abelson murine leukemia viral oncogene homolog 1; AltName: Full=Proto-oncogene c-Abl; AltName: Full=p150
GenPept14740563 v-abl Abelson murine leukemia viral oncogene homolog 1 [Homo sapiens]
GenPept126541180 c-abl oncogene 1, receptor tyrosine kinase [Homo sapiens]
GenPept119608355v-abl Abelson murine leukemia viral oncogene homolog 1, isoform CRA_b
GenPept15298377 hypothetical protein XP_053261 [Homo sapiens]
GenBankAAB60394.1 proto-oncogene tyrosine-protein kinase [Homo sapiens]
GenBankEAW87949.1 v-abl Abelson murine leukemia viral oncogene homolog 1, isoform CRA_b [Homo sapiens]
GenBankEAW87948.1 v-abl Abelson murine leukemia viral oncogene homolog 1, isoform CRA_b [Homo sapiens]
ENSEMBLENSP00000266100Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.1.112) (p150) (c- ABL). [Homo sapiens]
EMBLCAM45754.1 
ENSEMBLENSP00000266100 
ENSEMBLENSP00000266100TDI sequence
ENSEMBLENSP00000323315