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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P22681
Original Database ID CU P22681
Organism Homo sapiens
Annotation recname: full=e3 ubiquitin-protein
ligase cbl;ec=6.3.2.-;altname:
full=signal tr ansduction protein
cbl;altname: full=proto-oncogene
c-cbl;altname: fu ...
Sequence Length 906
 

SNP Information

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ResidueAA-Residue
Variants
InterfaceLigandStabilityValidated
5 SNPs found but only 0 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
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Cross-references

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Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1yvhcrystal structure of the c-cbl tkb domain in complex with the aps ptyr-618 phosphopeptide
DBALI1yvhA 
CATH1.20.930.20 Domain: 1yvhA01 Transcription Elongation Factor S-II; Chain A (100%)
CATH1.10.238.10 Domain: 1yvhA02 EF-hand (100%)
CATH3.30.505.10 Domain: 1yvhA03 SHC Adaptor Protein (100%)
JenaImageLibrary1yvh 
Target Sequence
UniProtKBP22681RecName: Full=E3 ubiquitin-protein ligase CBL;EC=6.3.2.-;AltName: Full=Signal transduction protein CBL;AltName: Full=Proto-oncogene c-CBL;AltName: Full=Casitas B-lineage lymphoma proto-oncogene;AltNam
InterProP22681 
PFAMP22681 
ProdomP22681 
GenPept115855CBL_HUMAN SIGNAL TRANSDUCTION PROTEIN CBL (PROTO-ONCOGENE C-CBL)
GenPept280867A43817 transforming protein (cbl) - human
GenPept29731c-cbl
GenPept397148556Sequence 406 from patent US 8211634
GenPept4885117 Cas-Br-M (murine) ecotropic retroviral transforming sequence; Cas-Br-M ecotropic retroviral transforming sequence (Onco
EMBLCAA40393.1 
UCSCGenomeBrowserP22681