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ModBase: Database of Comparative Protein Structure Models

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Sequence Information

Primary Database Link D6W552
Original Database ID EN ENSP00000264705.3
Organism Homo sapiens
Annotation subname: full=carbamoyl-phosphate
synthetase 2, aspartate transcarbamylase,
and dihydroorotase, isoform cra_a;
Sequence Length 2225

Dataset Information:

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Model Information

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Target Region385-1475
Protein Length2225
Template PDB Code1bxrA
Template Region2-1073
Sequence Identity40%
E-Value0
GA3411
MPQS0.811037
z-DOPE-0.72
TSVMod MethodMSRED
TSVMod RMSD0.852
TSVMod NO350.898
Datasetuniprot_subset_C1
ModPipe VersionSVN.r1372
Model Date2012-10-07

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in advanced pancreatic tumor for CCDS1742.1 G1286E
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1bxrstructure of carbamoyl phosphate synthetase complexed with the atp analog amppnp ; EC: 6.3.5.5 ; PFAM: PF00117 PF00289 PF00988 PF02142 PF02786 PF02787 ; SCOP: 18570 31499 31697 31698 41542 41543
DBALI1bxrA 
CATH3.40.50.20 Domain: 1bxrA01 Rossmann fold (99%)
CATH3.30.470.20 Domain: 1bxrA02 ATP-grasp fold, B domain (100%)
CATH3.30.1490.20 Domain: 1bxrA03 ATP-grasp fold, A domain (100%)
CATH1.10.1030.10 Domain: 1bxrA04 Carbamoyl Phosphate Synthetase; Chain A, domain 4 (100%)
CATH3.40.50.20 Domain: 1bxrA05 Rossmann fold (100%)
CATH3.30.470.20 Domain: 1bxrA06 ATP-grasp fold, B domain (100%)
CATH3.30.1490.20 Domain: 1bxrA07 ATP-grasp fold, A domain (100%)
CATH3.40.50.1380 Domain: 1bxrA08 Rossmann fold (100%)
JenaImageLibrary1bxr 
Target Sequence
UniProtKBD6W552RecName: Full=CAD protein;Includes:RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase;EC=6.3.5.5;Includes:RecName: Full=Aspartate carbamoyltransferase;EC=2.1.3.2;Includes:RecName: Full=Dih
InterProD6W552 
PFAMD6W552 
ProdomD6W552 
UniProtKBQ6P0Q0RecName: Full=CAD protein;Includes:RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase;EC=6.3.5.5;Includes:RecName: Full=Aspartate carbamoyltransferase;EC=2.1.3.2;Includes:RecName: Full=Dih
InterProQ6P0Q0 
PFAMQ6P0Q0 
ProdomQ6P0Q0 
UniProtKBP27708RecName: Full=CAD protein;Includes:RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase;EC=6.3.5.5;Includes:RecName: Full=Aspartate carbamoyltransferase;EC=2.1.3.2;Includes:RecName: Full=Dih
InterProP27708 
PFAMP27708 
ProdomP27708 
UniProtKBD6W552SubName: Full=Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a;
InterProD6W552 
PFAMD6W552 
ProdomD6W552 
UniProtKBD6W552RecName: Full=CAD protein;Includes:RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase;EC=6.3.5.5;Includes:RecName: Full=Aspartate carbamoyltransferase;EC=2.1.3.2;Includes:RecName: Full=Dih
InterProD6W552 
PFAMD6W552 
ProdomD6W552 
UniProtKBQ96CK3RecName: Full=CAD protein;Includes:RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase;EC=6.3.5.5;Includes:RecName: Full=Aspartate carbamoyltransferase;EC=2.1.3.2;Includes:RecName: Full=Dih
InterProQ96CK3 
PFAMQ96CK3 
ProdomQ96CK3 
UniProtKBP27708RecName: Full=CAD protein;Includes:RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase;EC=6.3.5.5;Includes:RecName: Full=Aspartate carbamoyltransferase;EC=2.1.3.2;Includes:RecName: Full=Dih
InterProP27708 
PFAMP27708 
ProdomP27708 
UniProtKBP27708.3PYR1_HUMAN RecName: Full=CAD protein; Includes: RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase; Includes: RecName: Full=Aspartate carbamoyltransferase; Includes: RecName: Full=Dihydroo
InterProP27708.3 
PFAMP27708.3 
ProdomP27708.3 
UniProtKBQ6P0Q0RecName: Full=CAD protein;Includes:RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase;EC=6.3.5.5;Includes:RecName: Full=Aspartate carbamoyltransferase;EC=2.1.3.2;Includes:RecName: Full=Dih
InterProQ6P0Q0 
PFAMQ6P0Q0 
ProdomQ6P0Q0 
RefSeqNP_004332.2 CAD protein [Homo sapiens]
GenPept50403731PYR1_HUMAN RecName: Full=CAD protein; Includes: RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase; Includes: RecName: Full=Aspartate carbamoyltransferase; Includes: RecName: Full=Dihydroo
GenPept41351087Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
GenPept344968853Sequence 1659 from patent US 7998689
GenPept344968852Sequence 1658 from patent US 7998689
GenPept344968851Sequence 1657 from patent US 7998689
GenPept344968849Sequence 1655 from patent US 7998689
GenPept119621018carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a
GenPept119621019carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a
GenPept18105007 CAD protein [Homo sapiens]
GenPept281037498Sequence 1655 from patent US 7608413
GenPept281037500Sequence 1657 from patent US 7608413
GenPept281037501Sequence 1658 from patent US 7608413
GenPept119621017carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a
GenPept314881274Sequence 1516 from patent US 7842467
GenPept281037502Sequence 1659 from patent US 7608413
GenPept331630682Sequence 852 from patent US 7919467
GenPept314881276Sequence 1518 from patent US 7842467
GenPept314881272Sequence 1514 from patent US 7842467
GenPept314881275Sequence 1517 from patent US 7842467
GenBankAAH65510.1 Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [Homo sapiens]
GenBankEAX00612.1 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a [Homo sapiens]
GenBankEAX00614.1 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a [Homo sapiens]
GenBankEAX00613.1 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a [Homo sapiens]
ENSEMBLENSP00000264705CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]. [Homo sapiens]
ENSEMBLENSP00000264705 
ENSEMBLENSP00000264705TDI sequence
ENSEMBLENSP00000264705