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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link 1228049
Original Database ID gi 1228049
Organism Homo sapiens
Annotation multifunctional protein cad
Sequence Length 2225

Dataset Information:

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Model Information

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Target Region388-1440
Protein Length2225
Template PDB Code1a9xA
Template Region2-1054
Sequence Identity40%
E-Value0e+00
GA3411
Datasetsnp-human2
ModPipe VersionModPipe1.0
Model Date2005-03-28

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in advanced pancreatic tumor for CCDS1742.1 G1286E
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1a9xcarbamoyl phosphate synthetase: caught in the act of glutamine hydrolysis ; EC: 6.3.5.5 ; PFAM: PF00117 PF00988 ; SCOP: 18550 31479 31657 31658 41502 41503
DBALI1a9xA 
CATH3.40.50.20 Domain: 1a9xA01 Rossmann fold (99%)
CATH3.30.470.20 Domain: 1a9xA02 ATP-grasp fold, B domain (100%)
CATH3.30.1490.20 Domain: 1a9xA03 ATP-grasp fold, A domain (100%)
CATH1.10.1030.10 Domain: 1a9xA04 Carbamoyl Phosphate Synthetase; Chain A, domain 4 (100%)
CATH3.40.50.20 Domain: 1a9xA05 Rossmann fold (100%)
CATH3.30.470.20 Domain: 1a9xA06 ATP-grasp fold, B domain (100%)
CATH3.30.1490.20 Domain: 1a9xA07 ATP-grasp fold, A domain (100%)
CATH3.40.50.1380 Domain: 1a9xA08 Rossmann fold (100%)
JenaImageLibrary1a9x 
Target Sequence
UniProtKBP27708CAD protein [Includes: Glutamine-dependent carbamoyl-phosphateDE synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2);DE Dihydroorotase (EC 3.5.2.3)]
InterProP27708 
PFAMP27708 
ProdomP27708 
GenPept1228049multifunctional protein CAD
GenPept1709955PYR1_HUMAN CAD PROTEIN [INCLUDES: GLUTAMINE-DEPENDENT CARBAMOYL-PHOSPHATE SYNTHASE ; ASPARTATE CARBAMOYLTRANSFERASE ; DI
GenPept281037499Sequence 1656 from patent US 7608413
GenPept314881273Sequence 1515 from patent US 7842467
GenPept344968850Sequence 1656 from patent US 7998689
GenPept4757896 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; CAD trifunctional protein of pyrimidi
UCSCGenomeBrowserP27708