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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link 1228049
Original Database ID gi 1228049
Organism Homo sapiens
Annotation multifunctional protein cad
Sequence Length 2225

Dataset Information:

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Model Information

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Target Region176-603
Protein Length2225
Template PDB Code1gpmA
Template Region8-525
Sequence Identity18%
E-Value2e-47
GA3410.52
DatasetSP/TR-2004
ModPipe VersionModPipe1.0
Model Date2004-10-12

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in advanced pancreatic tumor for CCDS1742.1 G1286E
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1gpmescherichia coli gmp synthetase complexed with amp and pyrophosphate ; EC: 6.3.5.2 ; PFAM: PF00117 PF00958 PF03054 ; SCOP: 31405 31608 38826
DBALI1gpmA 
CATH3.40.50.880 Domain: 1gpmA01 Rossmann fold (100%)
CATH3.40.50.620 Domain: 1gpmA02 Tyrosyl-Transfer RNA Synthetase , subunit E, domain 1 (100%)
CATH3.30.300.10 Domain: 1gpmA03 GMP Synthetase; Chain A, domain 3 (100%)
JenaImageLibrary1gpm 
Target Sequence
UniProtKBP27708CAD protein [Includes: Glutamine-dependent carbamoyl-phosphateDE synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2);DE Dihydroorotase (EC 3.5.2.3)]
InterProP27708 
PFAMP27708 
ProdomP27708 
GenPept1228049multifunctional protein CAD
GenPept1709955PYR1_HUMAN CAD PROTEIN [INCLUDES: GLUTAMINE-DEPENDENT CARBAMOYL-PHOSPHATE SYNTHASE ; ASPARTATE CARBAMOYLTRANSFERASE ; DI
GenPept281037499Sequence 1656 from patent US 7608413
GenPept314881273Sequence 1515 from patent US 7842467
GenPept344968850Sequence 1656 from patent US 7998689
GenPept4757896 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; CAD trifunctional protein of pyrimidi
UCSCGenomeBrowserP27708