University of California San Francisco | About UCSF | UCSF Benioff Children's Hospital San Francisco

ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link A8K8U5
Original Database ID sp P33981
Organism Homo sapiens, synthetic construct
Annotation recname: full=dual specificity
protein kinase ttk;ec=2.7.12.1;altname:
full=phos photyrosine picked threonine-protein
kinase;short=pyt;
Sequence Length 857

Dataset Information:

The newest dataset for this sequence was created on 2020-12-01. If you think that a better template has been added to the template database since, you can start a new calculation.

The calculation typically takes 1-2 days, and the results will be added to this page. Registered users will receive an email notification.

Information for additional models of this sequences are available by clicking on the model thumbnails below.  

Model Information

Perform action on this model:

Quality criteria indicate whether the model is considered
reliable (green) or unreliable (red).
 
Target Region525-792
Protein Length857
Template PDB Code3i6uA
Template Region220-487
Sequence Identity32%
E-Value2.3e-10
GA3411
MPQS0.505719
z-DOPE0.12
TSVMod MethodMSALL
TSVMod RMSD6.236
TSVMod NO350.696
DatasetMW-ch2
ModPipe VersionSVN.r1703
Model Date2020-12-01

Mouse over the images for more information

Sequence Model Coverage Summary
for all Models of this Sequence:

Filtered models for current sequence (Show all models)

 

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in advanced pancreatic tumor for CCDS4993.1 D697Y
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3i6ustructure and activation mechanism of the chk2 dna-damage checkpoint kinase
DBALI3i6uA 
JenaImageLibrary3i6u 
Target Sequence
UniProtKBQ9NTM0RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProQ9NTM0 
PFAMQ9NTM0 
ProdomQ9NTM0 
UniProtKBE1P543RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProE1P543 
PFAME1P543 
ProdomE1P543 
UniProtKBQ9BW51RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProQ9BW51 
PFAMQ9BW51 
ProdomQ9BW51 
UniProtKBA8K8U5RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProA8K8U5 
PFAMA8K8U5 
ProdomA8K8U5 
UniProtKBP33981RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProP33981 
PFAMP33981 
ProdomP33981 
UniProtKBQ5TCS0RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProQ5TCS0 
PFAMQ5TCS0 
ProdomQ5TCS0 
UniProtKBB2RDW2RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProB2RDW2 
PFAMB2RDW2 
ProdomB2RDW2 
UniProtKBQ15272RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProQ15272 
PFAMQ15272 
ProdomQ15272 
UniProtKBQ9NTM0TTK protein kinase.
InterProQ9NTM0 
PFAMQ9NTM0 
ProdomQ9NTM0 
UniProtKBB2RDW2SubName: Full=cDNA, FLJ96794, Homo sapiens TTK protein kinase (TTK), mRNA;
InterProB2RDW2 
PFAMB2RDW2 
ProdomB2RDW2 
UniProtKBQ9BW51TTK protein kinase.
InterProQ9BW51 
PFAMQ9BW51 
ProdomQ9BW51 
UniProtKBE1P543RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProE1P543 
PFAME1P543 
ProdomE1P543 
UniProtKBA8K8U5RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProA8K8U5 
PFAMA8K8U5 
ProdomA8K8U5 
UniProtKBB2RDW2RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProB2RDW2 
PFAMB2RDW2 
ProdomB2RDW2 
UniProtKBQ5TCS0RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProQ5TCS0 
PFAMQ5TCS0 
ProdomQ5TCS0 
UniProtKBP33981RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProP33981 
PFAMP33981 
ProdomP33981 
UniProtKBP33981.2TTK_HUMAN RecName: Full=Dual specificity protein kinase TTK; AltName: Full=Phosphotyrosine picked threonine-protein kinase; Short=PYT
InterProP33981.2 
PFAMP33981.2 
ProdomP33981.2 
UniProtKBQ15272RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProQ15272 
PFAMQ15272 
ProdomQ15272 
UniProtKBQ9NTM0RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProQ9NTM0 
PFAMQ9NTM0 
ProdomQ9NTM0 
UniProtKBQ9BW51RecName: Full=Dual specificity protein kinase TTK;EC=2.7.12.1;AltName: Full=Phosphotyrosine picked threonine-protein kinase;Short=PYT;
InterProQ9BW51 
PFAMQ9BW51 
ProdomQ9BW51 
RefSeqNP_003309.2 dual specificity protein kinase TTK isoform 1 [Homo sapiens]
GenPept568537534Sequence 30973 from patent US 8586006
GenPept568656364Sequence 2 from patent US 8614176
GenPept550593592unnamed protein product
GenPept577019659Sequence 16 from patent US 8623829
GenPept649103885TTK, partial
GenPept649121704TTK, partial
GenPept649151281TTK, partial
GenPept756616912Sequence 16 from patent US 8759481
GenPept545678765unnamed protein product
GenPept218598248unnamed protein product
GenPept550593566unnamed protein product
GenPept548945429unnamed protein product
GenPept545741834unnamed protein product
GenPept425817614unnamed protein product
GenPept425817571unnamed protein product
GenPept32693452unnamed protein product
GenPept314895716Sequence 2 from patent US 7847060
GenPept23308722 dual specificity protein kinase TTK isoform 1 [Homo sapiens]
GenPept23271249TTK protein kinase
GenPept228300173Sequence 2 from patent US 7507536
GenPept189055075unnamed protein product
GenPept160112977TTK_HUMAN RecName: Full=Dual specificity protein kinase TTK; AltName: Full=Phosphotyrosine picked threonine-protein kinase; Short=PYT
GenPept144994882Sequence 34 from patent US 7189507
GenPept12653697TTK protein kinase
GenPept123996949TTK protein kinase, partial
GenPept123982114TTK protein kinase
GenPept119569085TTK protein kinase, isoform CRA_a
GenPept119569084TTK protein kinase, isoform CRA_a
GenPept448991874unnamed protein product
GenPept448991892unnamed protein product
GenPept448991910unnamed protein product
GenPept545739602unnamed protein product
GenPept545739074unnamed protein product
GenPept545684982unnamed protein product
GenPept544339264unnamed protein product
GenPept544337576unnamed protein product
GenPept544332701unnamed protein product
GenPept544330389unnamed protein product
GenPept544091223Sequence 40 from patent US 8530430
GenPept534453989Sequence 2 from patent US 8492356
GenPept507842365Sequence 16 from patent US 8383590
GenPept448991928unnamed protein product
GenBankAAH00633.1 TTK protein kinase [Homo sapiens]
GenBankAAH32858.1 TTK protein kinase [Homo sapiens]
GenBankABM82886.1 TTK protein kinase [synthetic construct]
GenBankEAW48700.1 TTK protein kinase, isoform CRA_a [Homo sapiens]
GenBankABM86076.1 TTK protein kinase [synthetic construct]
GenBankEAW48699.1 TTK protein kinase, isoform CRA_a [Homo sapiens]
ENSEMBLENSP00000230510Dual specificity protein kinase TTK (EC 2.7.1.-) (Phosphotyrosine picked threonine kinase) (PYT). [Homo sapiens]
ENSEMBLENSP00000230510 
ENSEMBLENSP00000230510TDI sequence
ENSEMBLENSP00000358813 
UCSCGenomeBrowserQ9BW51