University of California San Francisco | About UCSF | UCSF Benioff Children's Hospital San Francisco

ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link P33981
Original Database ID SN P33981_chr6:80772328
Organism Homo sapiens
Annotation dual specificity protein kinase
ttk (ec 2.7.12.1) (phosphotyrosinepicked
threoni ne-protein kinase) (pyt)
Sequence Length 841

Dataset Information:

The newest dataset for this sequence was created on 2006-06-16. If you think that a better template has been added to the template database since, you can start a new calculation.

The calculation typically takes 1-2 days, and the results will be added to this page. Registered users will receive an email notification.

Information for additional models of this sequences are available by clicking on the model thumbnails below.  

Model Information

Perform action on this model:

Quality criteria indicate whether the model is considered
reliable (green) or unreliable (red).
 
Target Region370-776
Protein Length841
Template PDB Code1omwA
Template Region48-454
Sequence Identity17%
E-Value5e-49
GA3411
Datasetsnp-human4
ModPipe VersionModPipe1.0
Model Date2006-06-16

Mouse over the images for more information

Sequence Model Coverage Summary
for all Models of this Sequence:

Filtered models for current sequence (Show all models)

 

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in advanced pancreatic tumor for CCDS4993.1 D697Y
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1omwcrystal structure of the complex between g protein-coupled receptor kinase 2 and heterotrimeric g protein beta 1 and gamma 2 subunits ; EC: 2.7.1.126 ; PFAM: PF00069 PF00169 PF00400 PF00615 PF00631
DBALI1omwA 
CATH1.10.167.10 Domain: 1omwA02 Regulator of G-protein Signalling 4, domain 2 (100%)
CATH3.30.200.20 Domain: 1omwA03 Phosphorylase Kinase; domain 1 (46%)
CATH1.10.510.10 Domain: 1omwA04 Transferase(Phosphotransferase) domain 1 (90%)
JenaImageLibrary1omw 
Target Sequence
UniProtKBP33981Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosinepicked threonine-protein kinase) (PYT)
InterProP33981 
PFAMP33981 
ProdomP33981 
GenPept228211900Sequence 14 from patent US 7501242
GenPept228211938Sequence 14 from patent US 7501243
GenPept228211976Sequence 14 from patent US 7501244
GenPept330463742Sequence 14 from patent US 7867731
GenPept340011kinase
GenPept4507719 TTK protein kinase [Homo sapiens]
GenPept464971TTK_HUMAN DUAL SPECIFICITY PROTEIN KINASE TTK (PYT)
GenBankAAA61239.1 kinase [Homo sapiens]
UCSCGenomeBrowserP33981