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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link A0A096P5S8
Original Database ID NP_001356441.1
Organism Callithrix jacchus, Macaca fascicularis, etc.
Annotation recname: full=signal transducer
and activator of transcription
{eco:0000256|rule base:ru046415};
Sequence Length 770
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs1064122 R609 RS   *
rs1064121 R609 RS   *
rs1064110 Q288 QH  
rs17878478 M143 MI  
5 SNPs found but only 4 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
PharmGKB   PharmGKB data available for STAT3
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1bg1transcription factor stat3b/dna complex ; PFAM: PF00017 PF01017 PF02864 PF02865 ; SCOP: 17767 22461 40527
DBALI1bg1A 
CATH1.20.1050.20 Domain: 1bg1A01 Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 (100%)
CATH2.60.40.630 Domain: 1bg1A02 Immunoglobulin-like (100%)
CATH1.10.238.10 Domain: 1bg1A03 EF-hand (100%)
CATH3.30.505.10 Domain: 1bg1A04 SHC Adaptor Protein (100%)
JenaImageLibrary1bg1 
Target Sequence
UniProtKBQ9BW54RecName: Full=Signal transducer and activator of transcription 3;AltName: Full=Acute-phase response factor;
InterProQ9BW54 
PFAMQ9BW54 
ProdomQ9BW54 
UniProtKBU3BQV2RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};
InterProU3BQV2 
PFAMU3BQV2 
ProdomU3BQV2 
UniProtKBM3ZCB3RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};
InterProM3ZCB3 
PFAMM3ZCB3 
ProdomM3ZCB3 
UniProtKBA0A096P5S8RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};
InterProA0A096P5S8 
PFAMA0A096P5S8 
ProdomA0A096P5S8 
UniProtKBH2QD20RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};
InterProH2QD20 
PFAMH2QD20 
ProdomH2QD20 
UniProtKBA0A0D9S1T9RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};
InterProA0A0D9S1T9 
PFAMA0A0D9S1T9 
ProdomA0A0D9S1T9 
UniProtKBH9FYX9RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};
InterProH9FYX9 
PFAMH9FYX9 
ProdomH9FYX9 
UniProtKBM3VY01RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};
InterProM3VY01 
PFAMM3VY01 
ProdomM3VY01 
UniProtKBO14916RecName: Full=Signal transducer and activator of transcription 3;AltName: Full=Acute-phase response factor;
InterProO14916 
PFAMO14916 
ProdomO14916 
UniProtKBP40763RecName: Full=Signal transducer and activator of transcription 3;AltName: Full=Acute-phase response factor;
InterProP40763 
PFAMP40763 
ProdomP40763 
UniProtKBA8K7B8RecName: Full=Signal transducer and activator of transcription 3;AltName: Full=Acute-phase response factor;
InterProA8K7B8 
PFAMA8K7B8 
ProdomA8K7B8 
UniProtKBA0A671EFI2Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A671EFI2 
PFAMA0A671EFI2 
ProdomA0A671EFI2 
UniProtKBA0A673US23Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A673US23 
PFAMA0A673US23 
ProdomA0A673US23 
UniProtKBA0A6D2WYD9Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A6D2WYD9 
PFAMA0A6D2WYD9 
ProdomA0A6D2WYD9 
UniProtKBA0A6I9HZ34Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A6I9HZ34 
PFAMA0A6I9HZ34 
ProdomA0A6I9HZ34 
UniProtKBA0A6J1YJ01Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A6J1YJ01 
PFAMA0A6J1YJ01 
ProdomA0A6J1YJ01 
UniProtKBA0A667HL15Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A667HL15 
PFAMA0A667HL15 
ProdomA0A667HL15 
UniProtKBA0A485MPV6Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A485MPV6 
PFAMA0A485MPV6 
ProdomA0A485MPV6 
UniProtKBA0A455C2E0Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A455C2E0 
PFAMA0A455C2E0 
ProdomA0A455C2E0 
UniProtKBA0A452QT46Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A452QT46 
PFAMA0A452QT46 
ProdomA0A452QT46 
UniProtKBA0A3Q7X2U2Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A3Q7X2U2 
PFAMA0A3Q7X2U2 
ProdomA0A3Q7X2U2 
UniProtKBA0A3Q2L9H8Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A3Q2L9H8 
PFAMA0A3Q2L9H8 
ProdomA0A3Q2L9H8 
UniProtKBA0A384CYE5Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A384CYE5 
PFAMA0A384CYE5 
ProdomA0A384CYE5 
UniProtKBA0A383ZRV7Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A383ZRV7 
PFAMA0A383ZRV7 
ProdomA0A383ZRV7 
UniProtKBA0A2U4BPF6Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2U4BPF6 
PFAMA0A2U4BPF6 
ProdomA0A2U4BPF6 
UniProtKBA0A6P4UYW1SubName: Full=signal transducer and activator of transcription 3 isoform X1 {ECO:0000313|RefSeq:XP_019290901.1, ECO:0000313|RefSeq:XP_019290902.1}
InterProA0A6P4UYW1 
PFAMA0A6P4UYW1 
ProdomA0A6P4UYW1 
UniProtKBA0A7J7T977Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A7J7T977 
PFAMA0A7J7T977 
ProdomA0A7J7T977 
UniProtKBA0A7J8D2C8Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A7J8D2C8 
PFAMA0A7J8D2C8 
ProdomA0A7J8D2C8 
UniProtKBH9FYX9SubName: Full=Signal transducer and activator of transcription 3 isoform 1;
InterProH9FYX9 
PFAMH9FYX9 
ProdomH9FYX9 
UniProtKBH2QD20SubName: Full=Uncharacterized protein;
InterProH2QD20 
PFAMH2QD20 
ProdomH2QD20 
UniProtKBG1RLB0SubName: Full=Uncharacterized protein;
InterProG1RLB0 
PFAMG1RLB0 
ProdomG1RLB0 
UniProtKBA0A9V1EXG9SubName: Full=Signal transducer and activator of transcription 3 isoform X1 {ECO:0000313|RefSeq:XP_019290901.1, ECO:0000313|RefSeq:XP_019290902.1}
InterProA0A9V1EXG9 
PFAMA0A9V1EXG9 
ProdomA0A9V1EXG9 
UniProtKBA0A8M1GYV8SubName: Full=signal transducer and activator of transcription 3 isoform X1 {ECO:0000313|RefSeq:XP_040496534.1}
InterProA0A8M1GYV8 
PFAMA0A8M1GYV8 
ProdomA0A8M1GYV8 
UniProtKBA0A8D2JZA7SubName: Full=Signal transducer and activator of transcription 3 {ECO:0000313|Ensembl:ENSTGEP00000012047}
InterProA0A8D2JZA7 
PFAMA0A8D2JZA7 
ProdomA0A8D2JZA7 
UniProtKBA0A8D2ARX6SubName: Full=Signal transducer and activator of transcription 3 {ECO:0000313|Ensembl:ENSSVLP00005005543}
InterProA0A8D2ARX6 
PFAMA0A8D2ARX6 
ProdomA0A8D2ARX6 
UniProtKBA0A8C9M480SubName: Full=Signal transducer and activator of transcription 3 {ECO:0000313|Ensembl:ENSPTIP00000007211}
InterProA0A8C9M480 
PFAMA0A8C9M480 
ProdomA0A8C9M480 
UniProtKBA0A8C8WYC8SubName: Full=Signal transducer and activator of transcription 3 {ECO:0000313|Ensembl:ENSPLOP00000009624}
InterProA0A8C8WYC8 
PFAMA0A8C8WYC8 
ProdomA0A8C8WYC8 
UniProtKBA0A8C6QE18SubName: Full=Signal transducer and activator of transcription 3 {ECO:0000313|Ensembl:ENSNGAP00000002603}
InterProA0A8C6QE18 
PFAMA0A8C6QE18 
ProdomA0A8C6QE18 
UniProtKBA0A8C5YXK3SubName: Full=Signal transducer and activator of transcription 3 {ECO:0000313|Ensembl:ENSMMMP00000006559}
InterProA0A8C5YXK3 
PFAMA0A8C5YXK3 
ProdomA0A8C5YXK3 
UniProtKBA0A8C4LNY2SubName: Full=Signal transducer and activator of transcription 3 {ECO:0000313|Ensembl:ENSEASP00005014293}
InterProA0A8C4LNY2 
PFAMA0A8C4LNY2 
ProdomA0A8C4LNY2 
UniProtKBA0A8B8WAZ3SubName: Full=signal transducer and activator of transcription 3 isoform X1 {ECO:0000313|RefSeq:XP_036694304.1}
InterProA0A8B8WAZ3 
PFAMA0A8B8WAZ3 
ProdomA0A8B8WAZ3 
UniProtKBA0A8B8R546SubName: Full=signal transducer and activator of transcription 3 isoform X1 {ECO:0000313|RefSeq:XP_032313112.1, ECO:0000313|RefSeq:XP_032313113.1}
InterProA0A8B8R546 
PFAMA0A8B8R546 
ProdomA0A8B8R546 
UniProtKBA0A8B7TA76SubName: Full=signal transducer and activator of transcription 3 isoform X1 {ECO:0000313|RefSeq:XP_019522606.1}
InterProA0A8B7TA76 
PFAMA0A8B7TA76 
ProdomA0A8B7TA76 
UniProtKBO14916Transcription factor (Signal transducer and activator of transcriptionDE 3) (Hypothetical protein)
InterProO14916 
PFAMO14916 
ProdomO14916 
UniProtKBA0A2R9CC53Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2R9CC53 
PFAMA0A2R9CC53 
ProdomA0A2R9CC53 
UniProtKBA0A2I2Z8R2Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2I2Z8R2 
PFAMA0A2I2Z8R2 
ProdomA0A2I2Z8R2 
UniProtKBA0A2I3MP47Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2I3MP47 
PFAMA0A2I3MP47 
ProdomA0A2I3MP47 
UniProtKBA0A2I3SFL1Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2I3SFL1 
PFAMA0A2I3SFL1 
ProdomA0A2I3SFL1 
UniProtKBA0A2J8KFU9Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2J8KFU9 
PFAMA0A2J8KFU9 
ProdomA0A2J8KFU9 
UniProtKBA0A2J8RF43Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2J8RF43 
PFAMA0A2J8RF43 
ProdomA0A2J8RF43 
UniProtKBA0A2K5QPU4Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2K5QPU4 
PFAMA0A2K5QPU4 
ProdomA0A2K5QPU4 
UniProtKBA0A2K5TRQ7Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2K5TRQ7 
PFAMA0A2K5TRQ7 
ProdomA0A2K5TRQ7 
UniProtKBA0A2K5TRU8Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2K5TRU8 
PFAMA0A2K5TRU8 
ProdomA0A2K5TRU8 
UniProtKBA0A2K6PPE4Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}
InterProA0A2K6PPE4 
PFAMA0A2K6PPE4 
ProdomA0A2K6PPE4 
UniProtKBA8K7B8RecName: Full=Signal transducer and activator of transcription 3;AltName: Full=Acute-phase response factor;
InterProA8K7B8 
PFAMA8K7B8 
ProdomA8K7B8 
UniProtKBK7ENL3RecName: Full=Signal transducer and activator of transcription 3;AltName: Full=Acute-phase response factor;
InterProK7ENL3 
PFAMK7ENL3 
ProdomK7ENL3 
UniProtKBP40763RecName: Full=Signal transducer and activator of transcription 3;AltName: Full=Acute-phase response factor;
InterProP40763 
PFAMP40763 
ProdomP40763 
UniProtKBP40763.2STAT3_HUMAN RecName: Full=Signal transducer and activator of transcription 3; AltName: Full=Acute-phase response factor
InterProP40763.2 
PFAMP40763.2 
ProdomP40763.2 
UniProtKBQ9BW54RecName: Full=Signal transducer and activator of transcription 3;AltName: Full=Acute-phase response factor;
InterProQ9BW54 
PFAMQ9BW54 
ProdomQ9BW54 
UniProtKBO14916RecName: Full=Signal transducer and activator of transcription 3;AltName: Full=Acute-phase response factor;
InterProO14916 
PFAMO14916 
ProdomO14916 
RefSeqXP_004655421.1PREDICTED: signal transducer and activator of transcription 3 isoform X2
RefSeqNP_001356441.1signal transducer and activator of transcription 3 isoform 1
RefSeqXP_027802824.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_012299336.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_030151414.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_023507356.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_029783332.1signal transducer and activator of transcription 3 isoform X2
RefSeqXP_006092428.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_008964734.2signal transducer and activator of transcription 3 isoform X1
RefSeqNP_001356442.1signal transducer and activator of transcription 3 isoform 1
RefSeqNP_644805.1 signal transducer and activator of transcription 3 isoform 1 [Homo sapiens]
RefSeqXP_008833515.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_008147580.2signal transducer and activator of transcription 3 isoform X1
RefSeqXP_040496534.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_010980087.2signal transducer and activator of transcription 3 isoform X1
RefSeqXP_030663972.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_019522606.1PREDICTED: signal transducer and activator of transcription 3 isoform X1
RefSeqXP_029783333.1signal transducer and activator of transcription 3 isoform X2
RefSeqXP_012299335.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_014402723.1PREDICTED: signal transducer and activator of transcription 3 isoform X5
RefSeqXP_006092427.2signal transducer and activator of transcription 3 isoform X1
RefSeqXP_001109505.2 PREDICTED: signal transducer and activator of transcription 3 isoform 1 [Macaca mulatta]
RefSeqXP_008517426.1PREDICTED: signal transducer and activator of transcription 3 isoform X1
RefSeqXP_008964735.2signal transducer and activator of transcription 3 isoform X1
RefSeqXP_014689081.1PREDICTED: signal transducer and activator of transcription 3 isoform X1
RefSeqXP_015351167.1PREDICTED: signal transducer and activator of transcription 3 isoform X1
RefSeqXP_017499223.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_017499225.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_026950478.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_027802823.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_008147581.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_007087724.1PREDICTED: signal transducer and activator of transcription 3 isoform X1
RefSeqXP_004655420.1PREDICTED: signal transducer and activator of transcription 3 isoform X1
RefSeqXP_004434510.1PREDICTED: signal transducer and activator of transcription 3 isoform X1
RefSeqXP_016057675.1PREDICTED: signal transducer and activator of transcription 3 isoform X1
RefSeqXP_004282863.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_029783335.1signal transducer and activator of transcription 3 isoform X2
RefSeqXP_025216911.1signal transducer and activator of transcription 3 isoform X3
RefSeqXP_029420439.1signal transducer and activator of transcription 3 isoform X1
RefSeqXP_030151415.1signal transducer and activator of transcription 3 isoform X1
ENSEMBLENSP00000264657 
UCSCGenomeBrowserP40763