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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link O14636
Original Database ID WT_JAK2
Organism Homo sapiens
Annotation recname: full=tyrosine-protein
kinase jak2;ec=2.7.10.2;altname:
full=janus kinas e 2;short=jak-2;
Sequence Length 1132
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs10974946 E577 EK   X
rs17490221 D584 DE  
3 SNPs found but only 2 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB4oli
DBALI4oliA 
JenaImageLibrary4oli 
Target Sequence
UniProtKBO75297RecName: Full=Tyrosine-protein kinase JAK2;EC=2.7.10.2;AltName: Full=Janus kinase 2;Short=JAK-2;
InterProO75297 
PFAMO75297 
ProdomO75297 
UniProtKBO14636RecName: Full=Tyrosine-protein kinase JAK2;EC=2.7.10.2;AltName: Full=Janus kinase 2;Short=JAK-2;
InterProO14636 
PFAMO14636 
ProdomO14636 
UniProtKBO60674RecName: Full=Tyrosine-protein kinase JAK2;EC=2.7.10.2;AltName: Full=Janus kinase 2;Short=JAK-2;
InterProO60674 
PFAMO60674 
ProdomO60674 
UniProtKBO14636RecName: Full=Tyrosine-protein kinase JAK2;EC=2.7.10.2;AltName: Full=Janus kinase 2;Short=JAK-2;
InterProO14636 
PFAMO14636 
ProdomO14636 
UniProtKBO60674RecName: Full=Tyrosine-protein kinase JAK2;EC=2.7.10.2;AltName: Full=Janus kinase 2;Short=JAK-2;
InterProO60674 
PFAMO60674 
ProdomO60674 
UniProtKBO60674.2JAK2_HUMAN RecName: Full=Tyrosine-protein kinase JAK2; AltName: Full=Janus kinase 2; Short=JAK-2
InterProO60674.2 
PFAMO60674.2 
ProdomO60674.2 
UniProtKBO75297RecName: Full=Tyrosine-protein kinase JAK2;EC=2.7.10.2;AltName: Full=Janus kinase 2;Short=JAK-2;
InterProO75297 
PFAMO75297 
ProdomO75297 
RefSeqNP_004963.1 tyrosine-protein kinase JAK2 [Homo sapiens]
GenPept757873258Sequence 5 from patent US 8486941
GenPept756867630Sequence 2 from patent US 8841078
GenPept756656078Sequence 24 from patent US 8791112
GenPept756322237Sequence 116 from patent US 8680041
GenPept568535712Sequence 25541 from patent US 8586006
GenPept544156427Sequence 2 from patent US 8512948
GenPept12643404JAK2_HUMAN RecName: Full=Tyrosine-protein kinase JAK2; AltName: Full=Janus kinase 2; Short=JAK-2
GenPept14741727 Janus kinase 2 [Homo sapiens]
GenPept14741733 Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens]
GenPept14741745 Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens]
GenPept155076323Sequence 36 from patent US 7202033
GenPept17384438Janus kinase 2 (a protein tyrosine kinase)
GenPept2570359receptor-associated tyrosine kinase
GenPept119579178Janus kinase 2 (a protein tyrosine kinase)
GenPept314131284Sequence 6 from patent US 7740664
GenPept314504607Sequence 1 from patent US 7795206
GenPept443883515Sequence 2 from patent US 8349861
GenPept4826776 tyrosine-protein kinase JAK2 [Homo sapiens]
GenBankEAW58774.1 Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens]
GenBankAAB82092.1 receptor-associated tyrosine kinase [Homo sapiens]
ENSEMBLENSP00000212292Tyrosine-protein kinase JAK2 (EC 2.7.1.112) (Janus kinase 2) (JAK-2). [Homo sapiens]
EMBLCAD13329.1 
UCSCGenomeBrowserO60674 
ENSEMBLENSP00000212292 
ENSEMBLENSP00000212292TDI sequence
ENSEMBLENSP00000371067