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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link 53972289
Original Database ID SN Q13177_chr3:19799782
Organism Homo sapiens
Annotation sequence 1301 from patent us 6753314
Sequence Length 524
 

SNP Information

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ResidueAA-Residue
Variants
InterfaceLigandStabilityValidated
rs1046714 V414 VL  

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Cross-references

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Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1yhvcrystal structure of pak1 kinase domain with two point mutations (k299r, t423e)
DBALI1yhvA 
CATH3.30.200.20 Domain: 1yhvA01 Phosphorylase Kinase; domain 1 (100%)
CATH1.10.510.10 Domain: 1yhvA02 Transferase(Phosphotransferase) domain 1 (98%)
JenaImageLibrary1yhv 
Target Sequence
UniProtKBQ13177Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activatedDE kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase)
InterProQ13177 
PFAMQ13177 
ProdomQ13177 
GenPept155076333Sequence 46 from patent US 7202033
GenPept189702093Sequence 3 from patent US 7364887
GenPept3041712PAK2_HUMAN SERINE/THREONINE-PROTEIN KINASE PAK 2 (P21-ACTIVATED KINASE 2) (PAK-2) (PAK65) (GAMMA-PAK) (S6/H4 KINASE)
GenPept314881180Sequence 1422 from patent US 7842467
GenPept390162353Sequence 3 from patent US 8187828
GenPept53972289Sequence 1301 from patent US 6753314
UCSCGenomeBrowserQ13177