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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link Q05329
Original Database ID EN ENSP00000365437.3
Organism Homo sapiens
Annotation recname: full=glutamate decarboxylase
2;ec=4.1.1.15;altname: full=65
kda glutami c acid decarboxylase;short=gad-65;altname:
full=glutamate decarboxyla ...
Sequence Length 585
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs8190600 K124 KN  
rs8190671 K286 KR  
rs8190730 R375 RQ  
4 SNPs found but only 3 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in glioblastoma multiforme for CCDS7149.1 M415I
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB2okkthe x-ray crystal structure of the 65kda isoform of glutamic acid decarboxylase (gad65)
DBALI2okkA 
JenaImageLibrary2okk 
Target Sequence
UniProtKBQ5VZ30SubName: Full=Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) {ECO:0000313|EMBL:AAI26330.1};SubName: Full=Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa), isoform CRA_b {
InterProQ5VZ30 
PFAMQ5VZ30 
ProdomQ5VZ30 
UniProtKBQ05329RecName: Full=Glutamate decarboxylase 2;EC=4.1.1.15;AltName: Full=65 kDa glutamic acid decarboxylase;Short=GAD-65;AltName: Full=Glutamate decarboxylase 65 kDa isoform;
InterProQ05329 
PFAMQ05329 
ProdomQ05329 
UniProtKBQ9UD87RecName: Full=Glutamate decarboxylase 2;EC=4.1.1.15;AltName: Full=65 kDa glutamic acid decarboxylase;Short=GAD-65;AltName: Full=Glutamate decarboxylase 65 kDa isoform;
InterProQ9UD87 
PFAMQ9UD87 
ProdomQ9UD87 
UniProtKBQ5VZ30SubName: Full=Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa);SubName: Full=Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa), isoform CRA_b;
InterProQ5VZ30 
PFAMQ5VZ30 
ProdomQ5VZ30 
UniProtKBQ9UD87RecName: Full=Glutamate decarboxylase 2;EC=4.1.1.15;AltName: Full=65 kDa glutamic acid decarboxylase;Short=GAD-65;AltName: Full=Glutamate decarboxylase 65 kDa isoform;
InterProQ9UD87 
PFAMQ9UD87 
ProdomQ9UD87 
UniProtKBQ05329.1DCE2_HUMAN RecName: Full=Glutamate decarboxylase 2; AltName: Full=65 kDa glutamic acid decarboxylase; Short=GAD-65; AltName: Full=Glutamate decarboxylase 65 kDa isoform
InterProQ05329.1 
PFAMQ05329.1 
ProdomQ05329.1 
UniProtKBQ05329RecName: Full=Glutamate decarboxylase 2;EC=4.1.1.15;AltName: Full=65 kDa glutamic acid decarboxylase;Short=GAD-65;AltName: Full=Glutamate decarboxylase 65 kDa isoform;
InterProQ05329 
PFAMQ05329 
ProdomQ05329 
RefSeqNP_000809.1 glutamate decarboxylase 2 [Homo sapiens]
RefSeqNP_001127838.1 glutamate decarboxylase 2 [Homo sapiens]
GenPept507854079Sequence 194 from patent US 8378072
GenPept55662653glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GenPept56570516Sequence 6 from patent US 6770460
GenPept568527914Sequence 3081 from patent US 8586006
GenPept593007619Sequence 2 from patent US 8652488
GenPept5994224Sequence 57 from patent US 5846740
GenPept5994226Sequence 59 from patent US 5846740
GenPept756469681Sequence 2 from patent US 8735359
GenPept756734576Sequence 31 from patent US 8809290
GenPept914815626Sequence 57 from patent US 8926966
GenPept914815628Sequence 59 from patent US 8926966
GenPept119606508glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa), isoform CRA_b
GenPept4503875 glutamate decarboxylase 2 [Homo sapiens]
GenPept363841187Sequence 6 from patent US 8071563
GenPept10066201Sequence 57 from patent US 5998366
GenPept10066205Sequence 59 from patent US 5998366
GenPept10189809unnamed protein product
GenPept106112A41292 glutamate decarboxylase (EC 4.1.1.15) 2 - human
GenPept118835509Glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GenPept14736365 glutamate decarboxylase 2 [Homo sapiens]
GenPept118835645Glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GenPept119606509glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa), isoform CRA_b
GenPept14736367 glutamate decarboxylase 2 [Homo sapiens]
GenPept1612192Sequence 2 from patent US 5547847
GenPept182932glutamate decarboxylase
GenPept32815084glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GenPept313883158glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (GAD2), transcript variant 2, partial
GenPept27273748Sequence 59 from patent US 6455267
GenPept27273746Sequence 57 from patent US 6455267
GenPept261859192glutamate decarboxylase 2, partial
GenPept239653248Sequence 6 from patent US 7527785
GenPept197276620 glutamate decarboxylase 2 [Homo sapiens]
GenPept182934glutamate decarboxylase
GenPept1352216DCE2_HUMAN RecName: Full=Glutamate decarboxylase 2; AltName: Full=65 kDa glutamic acid decarboxylase; Short=GAD-65; AltName: Full=Glutamate decarboxylase 65 kDa isoform
GenBankEAW86103.1 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa), isoform CRA_b [Homo sapiens]
GenBankEAW86102.1 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa), isoform CRA_b [Homo sapiens]
GenBankAAP88040.1 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) [Homo sapiens]
GenBankAAI26330.1 Glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) [Homo sapiens]
GenBankAAI26328.1 Glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) [Homo sapiens]
GenBankAAA62367.1 glutamate decarboxylase [Homo sapiens]
GenBankAAA58491.1 glutamate decarboxylase [Homo sapiens]
ENSEMBLENSP00000259271Glutamate decarboxylase, 65 kDa isoform (EC 4.1.1.15) (GAD-65) (65 kDa glutamic acid decarboxylase). [Homo sapiens]
EMBLCAH73659.1 
ENSEMBLENSP00000259271 
ENSEMBLENSP00000259271TDI sequence
ENSEMBLENSP00000365437 
UCSCGenomeBrowserQ05329