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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link G4XH65
Original Database ID sp P03372
Organism Homo sapiens, synthetic construct
Annotation subname: full=estrogen nuclear
receptor alpha;
Sequence Length 595
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
4 SNPs found but only 0 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in glioblastoma multiforme for CCDS5234.1 S341L
PharmGKB   PharmGKB data available for ESR1
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB6sbo
DBALI6sboB 
JenaImageLibrary6sbo 
Target Sequence
UniProtKBQ9UIS7RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ9UIS7 
PFAMQ9UIS7 
ProdomQ9UIS7 
UniProtKBQ14276RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ14276 
PFAMQ14276 
ProdomQ14276 
UniProtKBQ5T5H7RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ5T5H7 
PFAMQ5T5H7 
ProdomQ5T5H7 
UniProtKBQ13511RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ13511 
PFAMQ13511 
ProdomQ13511 
UniProtKBP03372RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProP03372 
PFAMP03372 
ProdomP03372 
UniProtKBQ6MZQ9RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ6MZQ9 
PFAMQ6MZQ9 
ProdomQ6MZQ9 
UniProtKBQ9NU51RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ9NU51 
PFAMQ9NU51 
ProdomQ9NU51 
UniProtKBG4XH65RecName: Full=Estrogen receptor {ECO:0000256|PIRNR:PIRNR002527};Short=ER {ECO:0000256|PIRNR:PIRNR002527};AltName: Full=ER-alpha {ECO:0000256|PIRNR:PIRNR002527};AltName: Full=Estradiol receptor {ECO:00
InterProG4XH65 
PFAMG4XH65 
ProdomG4XH65 
UniProtKBQ9UDZ7RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ9UDZ7 
PFAMQ9UDZ7 
ProdomQ9UDZ7 
UniProtKBQ5TFI3Estrogen receptor 1
InterProQ5TFI3 
PFAMQ5TFI3 
ProdomQ5TFI3 
UniProtKBG4XH65SubName: Full=Estrogen nuclear receptor alpha;
InterProG4XH65 
PFAMG4XH65 
ProdomG4XH65 
UniProtKBQ5SYS0Estrogen receptor 1 (Estrogen receptor 1, isoform CRA_a).
InterProQ5SYS0 
PFAMQ5SYS0 
ProdomQ5SYS0 
UniProtKBQ5T5H7SubName: Full=Estrogen receptor 1;SubName: Full=Estrogen receptor 1, isoform CRA_a;
InterProQ5T5H7 
PFAMQ5T5H7 
ProdomQ5T5H7 
UniProtKBQ13511RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ13511 
PFAMQ13511 
ProdomQ13511 
UniProtKBP03372.2ESR1_HUMAN RecName: Full=Estrogen receptor; Short=ER; AltName: Full=ER-alpha; AltName: Full=Estradiol receptor; AltName: Full=Nuclear receptor subfamily 3 group A member 1
InterProP03372.2 
PFAMP03372.2 
ProdomP03372.2 
UniProtKBP03372RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProP03372 
PFAMP03372 
ProdomP03372 
UniProtKBQ14276RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ14276 
PFAMQ14276 
ProdomQ14276 
UniProtKBQ5T5H7RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ5T5H7 
PFAMQ5T5H7 
ProdomQ5T5H7 
UniProtKBQ9UIS7RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ9UIS7 
PFAMQ9UIS7 
ProdomQ9UIS7 
UniProtKBQ6MZQ9RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ6MZQ9 
PFAMQ6MZQ9 
ProdomQ6MZQ9 
UniProtKBQ9NU51RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ9NU51 
PFAMQ9NU51 
ProdomQ9NU51 
UniProtKBQ9UDZ7RecName: Full=Estrogen receptor;Short=ER;AltName: Full=ER-alpha;AltName: Full=Estradiol receptor;AltName: Full=Nuclear receptor subfamily 3 group A member 1;
InterProQ9UDZ7 
PFAMQ9UDZ7 
ProdomQ9UDZ7 
RefSeqNP_000116.2 estrogen receptor isoform 1 [Homo sapiens]
RefSeqNP_001116212.1 estrogen receptor isoform 2 [Homo sapiens]
RefSeqNP_001116213.1 estrogen receptor isoform 3 [Homo sapiens]
RefSeqNP_001116214.1 estrogen receptor isoform 4 [Homo sapiens]
RefSeqNP_001372497.1estrogen receptor isoform 1
RefSeqNP_001372498.1estrogen receptor isoform 1
GenPept170295802 estrogen receptor isoform 3 [Homo sapiens]
GenPept915840276Sequence 19 from patent US 9012166
GenPept823674236ESR1, partial
GenPept757047108Sequence 27 from patent US 8900820
GenPept756203900Sequence 8 from patent US 8673589
GenPept684667445unnamed protein product
GenPept649099832ESR1, partial
GenPept114211521unnamed protein product
GenPept306921463estrogen receptor 1, partial
GenPept348019627estrogen nuclear receptor alpha
GenPept37499471estrogen receptor 1
GenPept375661056Sequence 27 from patent US 8088589
GenPept375722664Sequence 3 from patent US 8101352
GenPept380287552Sequence 27 from patent US 8129125
GenPept544090414Sequence 73 from patent US 8530168
GenPept544257ESR1_HUMAN RecName: Full=Estrogen receptor; Short=ER; AltName: Full=ER-alpha; AltName: Full=Estradiol receptor; AltName: Full=Nuclear receptor subfamily 3 group A member 1
GenPept228357185Sequence 9 from patent US 7514545
GenPept217269419Sequence 8 from patent US 7455988
GenPept21444273unnamed protein product
GenPept115838068Sequence 2 from patent US 7112715
GenPept118763947Estrogen receptor 1
GenPept118764400Estrogen receptor 1
GenPept119568125estrogen receptor 1, isoform CRA_a
GenPept15301634 estrogen receptor 1 [Homo sapiens]
GenPept15301642 estrogen receptor 1 [Homo sapiens]
GenPept170295800 estrogen receptor isoform 2 [Homo sapiens]
GenPept170295804 estrogen receptor isoform 4 [Homo sapiens]
GenPept55960977estrogen receptor 1
GenPept55960978estrogen receptor 1
GenPept56203351estrogen receptor 1
GenPept61357348estrogen receptor 1
GenPept60814879estrogen receptor 1
GenPept57208509estrogen receptor 1
GenPept57208508estrogen receptor 1
GenPept15121896Sequence 12 from patent US 6236946
GenPept62821794 estrogen receptor isoform 1 [Homo sapiens]
GenPept56203352estrogen receptor 1
GenPept56205104estrogen receptor 1
GenPept56205105estrogen receptor 1
GenPept568537777Sequence 32085 from patent US 8586006
GenBankAAX41375.1 estrogen receptor 1 [synthetic construct]
GenBankAAI28574.1 Estrogen receptor 1 [Homo sapiens]
GenBankAAI28575.1 Estrogen receptor 1 [Homo sapiens]
GenBankAAQ91815.1 estrogen receptor 1 [Homo sapiens]
GenBankAAX36323.1 estrogen receptor 1 [synthetic construct]
GenBankEAW47740.1 estrogen receptor 1, isoform CRA_a [Homo sapiens]
ENSEMBLENSP00000206249Estrogen receptor (ER) (Estradiol receptor) (ER-alpha). [Homo sapiens]
EMBLCAI14237.1 
EMBLCAI21012.1 
EMBLCAI22123.1 
EMBLCAI42285.1 
ENSEMBLENSP00000206249 
ENSEMBLENSP00000206249TDI sequence
ENSEMBLENSP00000342630