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ModBase: Database of Comparative Protein Structure Models

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Sequence Information

Primary Database Link P06241
Original Database ID EN ENSP00000346671.3
Organism Cercocebus atys, Cercocebus torquatus atys, etc.
Annotation recname: full=tyrosine-protein
kinase fyn;ec=2.7.10.2;altname:
full=proto-oncoge ne syn;altname:
full=proto-oncogene c-fyn;altname:
full=src-like kina ...
Sequence Length 537

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Information for additional models of this sequences are available by clicking on the model thumbnails below.  

Model Information

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Target Region83-537
Protein Length537
Template PDB Code1fmkA
Template Region82-533
Sequence Identity76%
E-Value0
GA3411
MPQS1.7178
z-DOPE-0.72
TSVMod MethodMSALL
TSVMod RMSD1.669
TSVMod NO350.941
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Sequence Model Coverage Summary
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Cross-references

Show obsolete/secondary identifiers
Template Structure
PDB1fmkcrystal structure of human tyrosine-protein kinase c-src ; EC: 2.7.1.112 ; PFAM: PF00017 PF00018 PF00069 ; SCOP: 24511 40436 41690
DBALI1fmkA 
CATH2.30.30.40 Domain: 1fmkA01 SH3 Domains (100%)
CATH3.30.505.10 Domain: 1fmkA02 SHC Adaptor Protein (100%)
CATH3.30.200.20 Domain: 1fmkA03 Phosphorylase Kinase; domain 1 (100%)
CATH1.10.510.10 Domain: 1fmkA04 Transferase(Phosphotransferase) domain 1 (100%)
JenaImageLibrary1fmk 
Target Sequence
UniProtKBQ8N5D7RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProQ8N5D7 
PFAMQ8N5D7 
ProdomQ8N5D7 
UniProtKBB5BU57RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProB5BU57 
PFAMB5BU57 
ProdomB5BU57 
UniProtKBH0UI48RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProH0UI48 
PFAMH0UI48 
ProdomH0UI48 
UniProtKBG7P3M8RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096};EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096, ECO:0000256|SAAS:SAAS00021209};
InterProG7P3M8 
PFAMG7P3M8 
ProdomG7P3M8 
UniProtKBA0A0D9RST7RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096};EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096, ECO:0000256|SAAS:SAAS00021209};
InterProA0A0D9RST7 
PFAMA0A0D9RST7 
ProdomA0A0D9RST7 
UniProtKBG7MQQ6RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096};EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096};
InterProG7MQQ6 
PFAMG7MQQ6 
ProdomG7MQQ6 
UniProtKBA0A096NW74RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096};EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096, ECO:0000256|SAAS:SAAS00021209};
InterProA0A096NW74 
PFAMA0A096NW74 
ProdomA0A096NW74 
UniProtKBG1TA73RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096};EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096, ECO:0000256|SAAS:SAAS00021209};
InterProG1TA73 
PFAMG1TA73 
ProdomG1TA73 
UniProtKBE1P557RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProE1P557 
PFAME1P557 
ProdomE1P557 
UniProtKBH2QTK7RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096};EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096};
InterProH2QTK7 
PFAMH2QTK7 
ProdomH2QTK7 
UniProtKBQ5R3A7RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProQ5R3A7 
PFAMQ5R3A7 
ProdomQ5R3A7 
UniProtKBP06241RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProP06241 
PFAMP06241 
ProdomP06241 
UniProtKBQ5R3A6RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProQ5R3A6 
PFAMQ5R3A6 
ProdomQ5R3A6 
UniProtKBQ16248RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProQ16248 
PFAMQ16248 
ProdomQ16248 
UniProtKBA0A2K6B9D1Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2K6B9D1 
PFAMA0A2K6B9D1 
ProdomA0A2K6B9D1 
UniProtKBA0A2K5YJ25Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2K5YJ25 
PFAMA0A2K5YJ25 
ProdomA0A2K5YJ25 
UniProtKBA0A2R9B759Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2R9B759 
PFAMA0A2R9B759 
ProdomA0A2R9B759 
UniProtKBA0A663DJ18Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A663DJ18 
PFAMA0A663DJ18 
ProdomA0A663DJ18 
UniProtKBA0A6D2Y4M7Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A6D2Y4M7 
PFAMA0A6D2Y4M7 
ProdomA0A6D2Y4M7 
UniProtKBA0A8C2VQG6SubName: Full=FYN proto-oncogene, Src family tyrosine kinase {ECO:0000313|Ensembl:ENSCLAP00000016014}
InterProA0A8C2VQG6 
PFAMA0A8C2VQG6 
ProdomA0A8C2VQG6 
UniProtKBA0A2J8PU83Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2J8PU83 
PFAMA0A2J8PU83 
ProdomA0A2J8PU83 
UniProtKBA0A2K6K4W3Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2K6K4W3 
PFAMA0A2K6K4W3 
ProdomA0A2K6K4W3 
UniProtKBA0A2K5TKI9Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2K5TKI9 
PFAMA0A2K5TKI9 
ProdomA0A2K5TKI9 
UniProtKBA0A2K5MDU1Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2K5MDU1 
PFAMA0A2K5MDU1 
ProdomA0A2K5MDU1 
UniProtKBA0A2I3HC72Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2I3HC72 
PFAMA0A2I3HC72 
ProdomA0A2I3HC72 
UniProtKBA0A2K5IMW1Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2K5IMW1 
PFAMA0A2K5IMW1 
ProdomA0A2K5IMW1 
UniProtKBA0A2I3SKP4Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2I3SKP4 
PFAMA0A2I3SKP4 
ProdomA0A2I3SKP4 
UniProtKBA0A2J8U1C4Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2J8U1C4 
PFAMA0A2J8U1C4 
ProdomA0A2J8U1C4 
UniProtKBA0A8C9I3W2SubName: Full=FYN proto-oncogene, Src family tyrosine kinase {ECO:0000313|Ensembl:ENSPTEP00000028759}
InterProA0A8C9I3W2 
PFAMA0A8C9I3W2 
ProdomA0A8C9I3W2 
UniProtKBA0A8J8XEI0Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A8J8XEI0 
PFAMA0A8J8XEI0 
ProdomA0A8J8XEI0 
UniProtKBG7P3M8SubName: Full=Putative uncharacterized protein;
InterProG7P3M8 
PFAMG7P3M8 
ProdomG7P3M8 
UniProtKBH2QTK7SubName: Full=Uncharacterized protein;
InterProH2QTK7 
PFAMH2QTK7 
ProdomH2QTK7 
UniProtKBQ5R3A7FYN oncogene related to SRC, FGR, YES
InterProQ5R3A7 
PFAMQ5R3A7 
ProdomQ5R3A7 
UniProtKBG7MQQ6SubName: Full=Tyrosine-protein kinase Fyn isoform a;
InterProG7MQQ6 
PFAMG7MQQ6 
ProdomG7MQQ6 
UniProtKBG1TA73SubName: Full=Uncharacterized protein;
InterProG1TA73 
PFAMG1TA73 
ProdomG1TA73 
UniProtKBG1RR57SubName: Full=Uncharacterized protein;
InterProG1RR57 
PFAMG1RR57 
ProdomG1RR57 
UniProtKBA0A8D2EAV6SubName: Full=FYN proto-oncogene, Src family tyrosine kinase {ECO:0000313|Ensembl:ENSTGEP00000003698}
InterProA0A8D2EAV6 
PFAMA0A8D2EAV6 
ProdomA0A8D2EAV6 
UniProtKBA0A2K6PQK4Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A2K6PQK4 
PFAMA0A2K6PQK4 
ProdomA0A2K6PQK4 
UniProtKBB5BU57SubName: Full=Protein-tyrosine kinase fyn isoform a (FYN oncogene related to SRC, FGR, YES, isoform CRA_a);
InterProB5BU57 
PFAMB5BU57 
ProdomB5BU57 
UniProtKBA0A8J8XFY0Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}
InterProA0A8J8XFY0 
PFAMA0A8J8XFY0 
ProdomA0A8J8XFY0 
UniProtKBQ8N5D7RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProQ8N5D7 
PFAMQ8N5D7 
ProdomQ8N5D7 
UniProtKBQ5R3A7RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProQ5R3A7 
PFAMQ5R3A7 
ProdomQ5R3A7 
UniProtKBQ16248RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProQ16248 
PFAMQ16248 
ProdomQ16248 
UniProtKBP06241.3FYN_HUMAN RecName: Full=Tyrosine-protein kinase Fyn; AltName: Full=Proto-oncogene Syn; AltName: Full=Proto-oncogene c-Fyn; AltName: Full=SLK; AltName: Full=p59-Fyn
InterProP06241.3 
PFAMP06241.3 
ProdomP06241.3 
UniProtKBP06241RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProP06241 
PFAMP06241 
ProdomP06241 
UniProtKBH0UI48RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProH0UI48 
PFAMH0UI48 
ProdomH0UI48 
UniProtKBE1P557RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProE1P557 
PFAME1P557 
ProdomE1P557 
UniProtKBB5BU57RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProB5BU57 
PFAMB5BU57 
ProdomB5BU57 
UniProtKBQ5R3A6RecName: Full=Tyrosine-protein kinase Fyn;EC=2.7.10.2;AltName: Full=Proto-oncogene Syn;AltName: Full=Proto-oncogene c-Fyn;AltName: Full=Src-like kinase;Short=SLK;AltName: Full=p59-Fyn;
InterProQ5R3A6 
PFAMQ5R3A6 
ProdomQ5R3A6 
RefSeqXP_001159043.1 PREDICTED: protein-tyrosine kinase fyn isoform 14 [Pan troglodytes]
RefSeqXP_021793659.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_023074820.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_030783992.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_030867969.1tyrosine-protein kinase Fyn isoform X1
RefSeqNP_002028.1 tyrosine-protein kinase Fyn isoform a [Homo sapiens]
RefSeqNP_001357458.1tyrosine-protein kinase Fyn isoform a
RefSeqXP_033090213.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_037856933.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_040839840.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_002817302.2tyrosine-protein kinase Fyn isoform X1
RefSeqXP_023074818.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_040839839.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_034818607.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_001159001.1 PREDICTED: protein-tyrosine kinase fyn isoform 13 [Pan troglodytes]
RefSeqXP_001158957.1 PREDICTED: protein-tyrosine kinase fyn isoform 12 [Pan troglodytes]
RefSeqXP_001158906.1 PREDICTED: protein-tyrosine kinase fyn isoform 11 [Pan troglodytes]
RefSeqXP_001158858.1 PREDICTED: protein-tyrosine kinase fyn isoform 10 [Pan troglodytes]
RefSeqXP_001158818.1 PREDICTED: protein-tyrosine kinase fyn isoform 9 [Pan troglodytes]
RefSeqXP_033090210.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_023074816.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_034818610.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_002714971.1 PREDICTED: proto-oncogene tyrosine-protein kinase fyn-like isoform 1 [Oryctolagus cuniculus]
RefSeqXP_030783991.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_033090211.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_023074821.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_028702877.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_037856934.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_001159198.1 PREDICTED: protein-tyrosine kinase fyn isoform 17 [Pan troglodytes]
RefSeqXP_040839838.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_518694.2 PREDICTED: protein-tyrosine kinase fyn isoform 21 [Pan troglodytes]
RefSeqXP_009240434.2tyrosine-protein kinase Fyn isoform X1
RefSeqXP_021793660.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_023074817.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_023074819.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_024213142.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_025238221.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_034818609.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_034818608.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_001159093.1 PREDICTED: protein-tyrosine kinase fyn isoform 15 [Pan troglodytes]
RefSeqXP_030783993.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_030867968.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_032012833.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_032012841.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_001159144.1 PREDICTED: protein-tyrosine kinase fyn isoform 16 [Pan troglodytes]
RefSeqXP_001159342.1 PREDICTED: protein-tyrosine kinase fyn isoform 20 [Pan troglodytes]
RefSeqXP_001159295.1 PREDICTED: protein-tyrosine kinase fyn isoform 19 [Pan troglodytes]
RefSeqXP_001159241.1 PREDICTED: protein-tyrosine kinase fyn isoform 18 [Pan troglodytes]
RefSeqXP_033090214.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_033090215.1tyrosine-protein kinase Fyn isoform X1
RefSeqXP_028702878.1tyrosine-protein kinase Fyn isoform X1
ENSEMBLENSP00000321899 
ENSEMBLENSP00000321899TDI sequence
ENSEMBLENSP00000346671