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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link E1P5F9
Original Database ID sp O14965
Organism Pan paniscus, Pan troglodytes, etc.
Annotation recname: full=aurora kinase a;ec=2.7.11.1;altname:
full=aurora 2;altname: full=a
urora/ipl1-related kinase 1;short=ark-1;short=aurora-related
kinase 1 ...
Sequence Length 403
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs11539196 G325 GW  
10 SNPs found but only 1 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3dlscrystal structure of human pas kinase bound to adp
DBALI3dlsA 
JenaImageLibrary3dls 
Target Sequence
UniProtKBQ9UPG5RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProQ9UPG5 
PFAMQ9UPG5 
ProdomQ9UPG5 
UniProtKBO14965RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProO14965 
PFAMO14965 
ProdomO14965 
UniProtKBE1P5F9RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProE1P5F9 
PFAME1P5F9 
ProdomE1P5F9 
UniProtKBO60445RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProO60445 
PFAMO60445 
ProdomO60445 
UniProtKBO75873RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProO75873 
PFAMO75873 
ProdomO75873 
UniProtKBQ9BQD6RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProQ9BQD6 
PFAMQ9BQD6 
ProdomQ9BQD6 
UniProtKBG2HFJ0SubName: Full=Aurora kinase A {ECO:0000313|EMBL:JAA07771.1};SubName: Full=Serine/threonine-protein kinase 6 {ECO:0000313|EMBL:BAK62498.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENS
InterProG2HFJ0 
PFAMG2HFJ0 
ProdomG2HFJ0 
UniProtKBQ9BQD6Serine/threonine kinase 15
InterProQ9BQD6 
PFAMQ9BQD6 
ProdomQ9BQD6 
UniProtKBA0A6D2Y5M9Aurora/IPL1-related kinase 1 {ECO:0000256|ARBA:ARBA00015383}EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513}AltName: Full=Serine/threonine-protein kinase aurora-A {ECO:0000256|ARBA:ARBA00021481}
InterProA0A6D2Y5M9 
PFAMA0A6D2Y5M9 
ProdomA0A6D2Y5M9 
UniProtKBA0A2R9ANX1Aurora/IPL1-related kinase 1 {ECO:0000256|ARBA:ARBA00015383}EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513}AltName: Full=Serine/threonine-protein kinase aurora-A {ECO:0000256|ARBA:ARBA00021481}
InterProA0A2R9ANX1 
PFAMA0A2R9ANX1 
ProdomA0A2R9ANX1 
UniProtKBA0A2J8JWB7Aurora/IPL1-related kinase 1 {ECO:0000256|ARBA:ARBA00015383}EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513}AltName: Full=Serine/threonine-protein kinase aurora-A {ECO:0000256|ARBA:ARBA00021481}
InterProA0A2J8JWB7 
PFAMA0A2J8JWB7 
ProdomA0A2J8JWB7 
UniProtKBG2HFJ0SubName: Full=Serine/threonine-protein kinase 6;SubName: Full=Uncharacterized protein;
InterProG2HFJ0 
PFAMG2HFJ0 
ProdomG2HFJ0 
UniProtKBE1P5F9RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProE1P5F9 
PFAME1P5F9 
ProdomE1P5F9 
UniProtKBO14965.2STK6_HUMAN RecName: Full=Serine/threonine-protein kinase 6; AltName: Full=Aurora kinase A; AltName: Full=Aurora/IPL1-related kinase 1; Short=ARK-1; Short=Aurora-related kinase 1; Short=hARK1; AltName:
InterProO14965.2 
PFAMO14965.2 
ProdomO14965.2 
UniProtKBO14965RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProO14965 
PFAMO14965 
ProdomO14965 
UniProtKBQ9UPG5RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProQ9UPG5 
PFAMQ9UPG5 
ProdomQ9UPG5 
UniProtKBQ9BQD6RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProQ9BQD6 
PFAMQ9BQD6 
ProdomQ9BQD6 
UniProtKBO75873RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProO75873 
PFAMO75873 
ProdomO75873 
UniProtKBO60445RecName: Full=Aurora kinase A;EC=2.7.11.1;AltName: Full=Aurora 2;AltName: Full=Aurora/IPL1-related kinase 1;Short=ARK-1;Short=Aurora-related kinase 1;Short=hARK1;AltName: Full=Breast tumor-amplified k
InterProO60445 
PFAMO60445 
ProdomO60445 
RefSeqXP_525364.2 PREDICTED: serine/threonine protein kinase 6 [Pan troglodytes]
PDB3EFWB Chain B, Structure Of Auroraa With Pyridyl-Pyrimidine Urea Inhibitor
PDB3EFWAChain A, Structure Of Auroraa With Pyridyl-Pyrimidine Urea Inhibitor
PDB3EFWBChain B, Structure Of Auroraa With Pyridyl-Pyrimidine Urea Inhibitor
GenPept343961821serine/threonine-protein kinase 6
GenPept47259849Sequence 4 from patent US 6716575
GenPept550869587Sequence 1 from patent US 8552018
GenPept59766493Sequence 4 from patent US 6841579
GenPept756521888Sequence 27 from patent US 8741559
GenPept915754456Sequence 1 from patent US 8999988
GenPept119595961aurora kinase A, isoform CRA_a
GenPept27923855STK6_HUMAN RecName: Full=Serine/threonine-protein kinase 6; AltName: Full=Aurora kinase A; AltName: Full=Aurora/IPL1-related kinase 1; Short=ARK-1; Short=Aurora-related kinase 1; Short=hARK1; AltName:
GenPept10052917Sequence 4 from patent US 5962312
GenPept119595968aurora kinase A, isoform CRA_c
GenPept119595956aurora kinase A, isoform CRA_a
GenPept119595967aurora kinase A, isoform CRA_a
GenPept119595965aurora kinase A, isoform CRA_a
GenPept119595964aurora kinase A, isoform CRA_a
GenPept119595963aurora kinase A, isoform CRA_a
GenPept119595962aurora kinase A, isoform CRA_a
GenPept119595960aurora kinase A, isoform CRA_a
GenPept119595959aurora kinase A, isoform CRA_a
GenPept119595958aurora kinase A, isoform CRA_a
GenPept119595957aurora kinase A, isoform CRA_a
GenPept118770492Sequence 4 from patent US 7119174
GenPept117644722hypothetical protein, partial
GenPept114682779 PREDICTED: serine/threonine protein kinase 6 [Pan troglodytes]
GenPept10056284Sequence 4 from patent US 5972676
GenPept123980734aurora kinase A
GenPept167340558Sequence 1 from patent US 7326712
GenPept13623611Aurora kinase A
GenPept14484181Sequence 4 from patent US 6207401
GenPept167237995Sequence 1 from patent US 7312226
GenPept12654873Aurora kinase A
GenPept167340569Sequence 1 from patent US 7326713
GenPept123995565aurora kinase A, partial
GenPept182928148Sequence 1 from patent US 7335662
GenPept20073237Aurora kinase A
GenPept208965846aurora kinase A, partial
GenPept218766694A Chain A, Structure Of Auroraa With Pyridyl-Pyrimidine Urea Inhibitor
GenPept218766695B Chain B, Structure Of Auroraa With Pyridyl-Pyrimidine Urea Inhibitor
GenPept12803361AURKA protein
GenBankABM82196.1 aurora kinase A [synthetic construct]
GenBankEAW75552.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankEAW75562.1 aurora kinase A, isoform CRA_c [Homo sapiens]
GenBankEAW75561.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankABM85384.1 aurora kinase A [synthetic construct]
GenBankAAH27464.1 Aurora kinase A [Homo sapiens]
GenBankAAH06423.1 Aurora kinase A [Homo sapiens]
GenBankEAW75550.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankEAW75551.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankAAH02499.1 AURKA protein [Homo sapiens]
GenBankEAW75553.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankEAW75554.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankEAW75555.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankAAH01280.1 Aurora kinase A [Homo sapiens]
GenBankEAW75557.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankEAW75558.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankEAW75559.1 aurora kinase A, isoform CRA_a [Homo sapiens]
GenBankEAW75556.1 aurora kinase A, isoform CRA_a [Homo sapiens]
EMBLCAL37826.1 
ENSEMBLENSPTRP00000023474 
ENSEMBLENSPTRP00000023475 
UCSCGenomeBrowserENSPTRT00000025433.1