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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link P06493
Original Database ID EN ENSP00000378699.3
Organism Gorilla gorilla gorilla, Pan paniscus, etc.
Annotation recname: full=cyclin-dependent
kinase 1;short=cdk1;ec=2.7.11.22;ec=2.7.11.23;alt
name: full=cell division control
protein 2 homolog;altname: full=cell
...
Sequence Length 297
 

SNP Information

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ResidueAA-Residue
Variants
InterfaceLigandStabilityValidated
rs17353714 R59 RG  
rs8755 R59 RG  
rs11540348 N288 ND *

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB6gu2
DBALI6gu2A 
JenaImageLibrary6gu2 
Target Sequence
UniProtKBG3RBW7SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000012982};
InterProG3RBW7 
PFAMG3RBW7 
ProdomG3RBW7 
UniProtKBH2R7P8SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|EMBL:JAA01287.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000050657};
InterProH2R7P8 
PFAMH2R7P8 
ProdomH2R7P8 
UniProtKBP06493RecName: Full=Cyclin-dependent kinase 1;Short=CDK1;EC=2.7.11.22;EC=2.7.11.23;AltName: Full=Cell division control protein 2 homolog;AltName: Full=Cell division protein kinase 1;AltName: Full=p34 protei
InterProP06493 
PFAMP06493 
ProdomP06493 
UniProtKBO60764RecName: Full=Cyclin-dependent kinase 1;Short=CDK1;EC=2.7.11.22;EC=2.7.11.23;AltName: Full=Cell division control protein 2 homolog;AltName: Full=Cell division protein kinase 1;AltName: Full=p34 protei
InterProO60764 
PFAMO60764 
ProdomO60764 
UniProtKBC9J497RecName: Full=Cyclin-dependent kinase 1;Short=CDK1;EC=2.7.11.22;EC=2.7.11.23;AltName: Full=Cell division control protein 2 homolog;AltName: Full=Cell division protein kinase 1;AltName: Full=p34 protei
InterProC9J497 
PFAMC9J497 
ProdomC9J497 
UniProtKBA8K7C4RecName: Full=Cyclin-dependent kinase 1;Short=CDK1;EC=2.7.11.22;EC=2.7.11.23;AltName: Full=Cell division control protein 2 homolog;AltName: Full=Cell division protein kinase 1;AltName: Full=p34 protei
InterProA8K7C4 
PFAMA8K7C4 
ProdomA8K7C4 
UniProtKBH2R7P8SubName: Full=Uncharacterized protein;
InterProH2R7P8 
PFAMH2R7P8 
ProdomH2R7P8 
UniProtKBG3RBW7SubName: Full=Uncharacterized protein;
InterProG3RBW7 
PFAMG3RBW7 
ProdomG3RBW7 
UniProtKBA0A2J8NVC9SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|EMBL:JAA01287.1, ECO:0000313|Ensembl:ENSPTRP00000050657}
InterProA0A2J8NVC9 
PFAMA0A2J8NVC9 
ProdomA0A2J8NVC9 
UniProtKBA8K7C4SubName: Full=cDNA FLJ76624, highly similar to Homo sapiens cell division cycle 2, G1 to S and G2 to M (CDC2), transcript variant 1, mRNA;
InterProA8K7C4 
PFAMA8K7C4 
ProdomA8K7C4 
UniProtKBA0A2J8WR14SubName: Full=CDK1 isoform 3 {ECO:0000313|EMBL:PNJ72210.1}
InterProA0A2J8WR14 
PFAMA0A2J8WR14 
ProdomA0A2J8WR14 
UniProtKBA0A6D2W3V2SubName: Full=CDK1 isoform 1 {ECO:0000313|EMBL:PNI75725.1}
InterProA0A6D2W3V2 
PFAMA0A6D2W3V2 
ProdomA0A6D2W3V2 
UniProtKBA0A2R9C1X9Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2R9C1X9 
PFAMA0A2R9C1X9 
ProdomA0A2R9C1X9 
UniProtKBP06493.1CDC2_HUMAN RecName: Full=Cell division control protein 2 homolog; AltName: Full=p34 protein kinase; AltName: Full=Cyclin-dependent kinase 1; Short=CDK1
InterProP06493.1 
PFAMP06493.1 
ProdomP06493.1 
UniProtKBO60764RecName: Full=Cyclin-dependent kinase 1;Short=CDK1;EC=2.7.11.22;EC=2.7.11.23;AltName: Full=Cell division control protein 2 homolog;AltName: Full=Cell division protein kinase 1;AltName: Full=p34 protei
InterProO60764 
PFAMO60764 
ProdomO60764 
UniProtKBP06493RecName: Full=Cyclin-dependent kinase 1;Short=CDK1;EC=2.7.11.22;EC=2.7.11.23;AltName: Full=Cell division control protein 2 homolog;AltName: Full=Cell division protein kinase 1;AltName: Full=p34 protei
InterProP06493 
PFAMP06493 
ProdomP06493 
UniProtKBA8K7C4RecName: Full=Cyclin-dependent kinase 1;Short=CDK1;EC=2.7.11.22;EC=2.7.11.23;AltName: Full=Cell division control protein 2 homolog;AltName: Full=Cell division protein kinase 1;AltName: Full=p34 protei
InterProA8K7C4 
PFAMA8K7C4 
ProdomA8K7C4 
UniProtKBC9J497RecName: Full=Cyclin-dependent kinase 1;Short=CDK1;EC=2.7.11.22;EC=2.7.11.23;AltName: Full=Cell division control protein 2 homolog;AltName: Full=Cell division protein kinase 1;AltName: Full=p34 protei
InterProC9J497 
PFAMC9J497 
ProdomC9J497 
RefSeqXP_034786515.1cyclin-dependent kinase 1 isoform X2
RefSeqNP_001777.1 cell division protein kinase 1 isoform 1 [Homo sapiens]
RefSeqXP_031993906.1cyclin-dependent kinase 1
RefSeqXP_003258288.3cyclin-dependent kinase 1 isoform X1
RefSeqXP_003258286.2cyclin-dependent kinase 1 isoform X1
RefSeqXP_001164774.1 PREDICTED: hypothetical protein isoform 5 [Pan troglodytes]
RefSeqXP_001164730.1 PREDICTED: hypothetical protein isoform 4 [Pan troglodytes]
RefSeqXP_001164695.1 PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]
RefSeqXP_507809.1 PREDICTED: hypothetical protein isoform 6 [Pan troglodytes]
1306392A1306392A gene CDC2
PDB4YC6EChain E, Cdk1/cks1
PDB4YC6CChain C, Cdk1/cks1
PDB4YC6AChain A, Cdk1/cks1
PDB4YC6GChain G, Cdk1/cks1
GenPept15778967Cell division cycle 2, G1 to S and G2 to M
GenPept87058A29539 protein kinase (EC 2.7.1.37) cdc2 - human
GenPept822599536G Chain G, Cdk1/cks1
GenPept822599534E Chain E, Cdk1/cks1
GenPept822599532C Chain C, Cdk1/cks1
GenPept114630643 PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]
GenPept114630645 PREDICTED: hypothetical protein isoform 4 [Pan troglodytes]
GenPept331631333Sequence 1503 from patent US 7919467
GenPept314882658Sequence 2900 from patent US 7842467
GenPept30582847cell division cycle 2, G1 to S and G2 to M
GenPept303110197Sequence 41 from patent US 7705120
GenPept29841unnamed protein product
GenPept29839unnamed protein product
GenPept23329329Sequence 12 from patent US 6428994
GenPept2255771306392A gene CDC2
GenPept21105791AF512554_1 cell division cycle 2, G1 to S and G2 to M
GenPept158257310unnamed protein product
GenPept155076293Sequence 6 from patent US 7202033
GenPept117646692hypothetical protein, partial
GenPept117646270hypothetical protein
GenPept115922CDC2_HUMAN RecName: Full=Cell division control protein 2 homolog; AltName: Full=p34 protein kinase; AltName: Full=Cyclin-dependent kinase 1; Short=CDK1
GenPept11430337 cell division cycle 2, G1 to S and G2 to M [Homo sapiens]
GenPept42663630Sequence 12 from patent US 6664086
GenPept822599530A Chain A, Cdk1/cks1
GenPept756521737Sequence 135 from patent US 8741556
GenPept756203636Sequence 95 from patent US 8673548
GenPept649150781CDK1, partial
GenPept649099069CDK1, partial
GenPept61362006cell division cycle 2
GenPept61362001cell division cycle 2
GenPept60813869cell division cycle 2
GenPept55633863 PREDICTED: hypothetical protein isoform 6 [Pan troglodytes]
GenPept4502709 cell division protein kinase 1 isoform 1 [Homo sapiens]
GenPept114630647 PREDICTED: cyclin-dependent kinase 1 isoform 5 [Pan troglodytes]
GenBankAAH14563.1 Cell division cycle 2, G1 to S and G2 to M [Homo sapiens]
GenBankAAM34793.1AF512554_1 cell division cycle 2, G1 to S and G2 to M [Homo sapiens]
GenBankAAP35650.1 cell division cycle 2, G1 to S and G2 to M [Homo sapiens]
GenBankAAX36278.1 cell division cycle 2 [synthetic construct]
GenBankAAX42138.1 cell division cycle 2 [synthetic construct]
GenBankAAX42139.1 cell division cycle 2 [synthetic construct]
EMBLCAL37461.1 
EMBLCAA68376.1 
EMBLCAA28963.1 
EMBLCAL38602.1 
ENSEMBLENSP00000378699 
UCSCGenomeBrowserP06493 
UCSCGenomeBrowserchr8_564.1