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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link 53971846
Original Database ID UP K2C8_HUMAN
Organism Homo sapiens
Annotation sequence 858 from patent us 6753314
Sequence Length 482
 

SNP Information

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ResidueAA-Residue
Variants
InterfaceLigandStabilityValidated
rs2277330 R400 RW   X
rs11554499 E278 EG  
rs11554280 D268 DY  
8 SNPs found but only 3 displayed. (SNPs in modeled regions)
 

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Cross-references

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Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1hcicrystal structure of the rod domain of alpha-actinin ; PFAM: PF00435 ; SCOP: 60950 60951 60952 60953
DBALI1hciA 
CATH1.20.58.60 Domain: 1hciA02 Methane Monooxygenase Hydroxylase; Chain G, domain 1 (100%)
CATH1.20.58.60 Domain: 1hciA03 Methane Monooxygenase Hydroxylase; Chain G, domain 1 (100%)
CATH1.20.58.60 Domain: 1hciA04 Methane Monooxygenase Hydroxylase; Chain G, domain 1 (72%)
JenaImageLibrary1hci 
Target Sequence
UniProtKBP05787Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keraton-8)DE (K8)
InterProP05787 
PFAMP05787 
ProdomP05787 
GenPept53971846Sequence 858 from patent US 6753314