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ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link A0A024R7M7
Original Database ID EN GENSCAN00000015468
Organism Homo sapiens
Annotation recname: full=tyrosine-protein
kinase {eco:0000256|rulebase:ru362096};ec=2.7.10.
2 {eco:0000256|rulebase:ru362096};
Sequence Length 1124
 

SNP Information

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SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs3179893 H879 HR  
rs1052526 D846 DH  
rs3213409 V722 VI   X
5 SNPs found but only 3 displayed. (SNPs in modeled regions)
 

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB4oli
DBALI4oliA 
JenaImageLibrary4oli 
Target Sequence
UniProtKBQ13259RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ13259 
PFAMQ13259 
ProdomQ13259 
UniProtKBQ13260RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ13260 
PFAMQ13260 
ProdomQ13260 
UniProtKBQ13611RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ13611 
PFAMQ13611 
ProdomQ13611 
UniProtKBP52333RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProP52333 
PFAMP52333 
ProdomP52333 
UniProtKBQ9Y6S2RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ9Y6S2 
PFAMQ9Y6S2 
ProdomQ9Y6S2 
UniProtKBQ99699RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ99699 
PFAMQ99699 
ProdomQ99699 
UniProtKBA0A024R7M7RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096};EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096};
InterProA0A024R7M7 
PFAMA0A024R7M7 
ProdomA0A024R7M7 
UniProtKBQ9Y6S2JAK3_HUMAN (Janus kinase 3) (a protein tyrosine kinase,DE leukocyte)
InterProQ9Y6S2 
PFAMQ9Y6S2 
ProdomQ9Y6S2 
UniProtKBP52333RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProP52333 
PFAMP52333 
ProdomP52333 
UniProtKBP52333.2JAK3_HUMAN RecName: Full=Tyrosine-protein kinase JAK3; AltName: Full=Janus kinase 3; Short=JAK-3; AltName: Full=Leukocyte janus kinase; Short=L-JAK
InterProP52333.2 
PFAMP52333.2 
ProdomP52333.2 
UniProtKBQ13259RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ13259 
PFAMQ13259 
ProdomQ13259 
UniProtKBQ8N1E8RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ8N1E8 
PFAMQ8N1E8 
ProdomQ8N1E8 
UniProtKBQ13260RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ13260 
PFAMQ13260 
ProdomQ13260 
UniProtKBQ13611RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ13611 
PFAMQ13611 
ProdomQ13611 
UniProtKBQ99699RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ99699 
PFAMQ99699 
ProdomQ99699 
UniProtKBQ9Y6S2RecName: Full=Tyrosine-protein kinase JAK3;EC=2.7.10.2;AltName: Full=Janus kinase 3;Short=JAK-3;AltName: Full=Leukocyte janus kinase;Short=L-JAK;
InterProQ9Y6S2 
PFAMQ9Y6S2 
ProdomQ9Y6S2 
RefSeqNP_000206.2 tyrosine-protein kinase JAK3 [Homo sapiens]
GenPept331628482Sequence 28 from patent US 7919261
GenPept757936833Sequence 5 from patent US 8609679
GenPept756656079Sequence 25 from patent US 8791112
GenPept756542468Sequence 5 from patent US 8748606
GenPept756398221Sequence 1 from patent US 8712749
GenPept443747086Sequence 5 from patent US 8338439
GenPept430388641Sequence 5 from patent US 8329901
GenPept397030892Sequence 463 from patent US 8216786
GenPept389968670Sequence 1 from patent US 8192972
GenPept343141390Sequence 5 from patent US 7982036
GenPept343109281Sequence 5 from patent US 7989465
GenPept259221450Sequence 1 from patent US 7558717
GenPept21263106AF513860_1 Janus kinase 3 (a protein tyrosine kinase, leukocyte)
GenPept14766251 Janus kinase 3 [Homo sapiens]
GenPept119605046Janus kinase 3 (a protein tyrosine kinase, leukocyte), isoform CRA_b
GenPept443883516Sequence 3 from patent US 8349861
GenPept4558771AC007201_2 JAK3_HUMAN
GenPept47157315 tyrosine-protein kinase JAK3 [Homo sapiens]
GenPept756397828Sequence 5 from patent US 8710222
GenPept568530428Sequence 9988 from patent US 8586006
GenPept510158143Sequence 5 from patent US 8450335
GenPept119605044Janus kinase 3 (a protein tyrosine kinase, leukocyte), isoform CRA_b
GenPept508119323Sequence 5 from patent US 8445498
GenPept50403745JAK3_HUMAN RecName: Full=Tyrosine-protein kinase JAK3; AltName: Full=Janus kinase 3; Short=JAK-3; AltName: Full=Leukocyte janus kinase; Short=L-JAK
GenBankEAW84638.1 Janus kinase 3 (a protein tyrosine kinase, leukocyte), isoform CRA_b [Homo sapiens]
GenBankEAW84640.1 Janus kinase 3 (a protein tyrosine kinase, leukocyte), isoform CRA_b [Homo sapiens]
GenBankAAD22741.1AC007201_2 JAK3_HUMAN [Homo sapiens]
GenBankAAM44860.1AF513860_1 Janus kinase 3 (a protein tyrosine kinase, leukocyte) [Homo sapiens]
ENSEMBLENSP00000355038Insulin-like 3 precursor (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor). [Homo sapiens]
ENSEMBLENSP00000355038 
ENSEMBLENSP00000355038TDI sequence
ENSEMBLGENSCAN00000008370 
ENSEMBLENSP00000432511