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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link Q13950.2
Original Database ID EN ENSP00000495497.1
Organism Pongo abelii, Homo sapiens
Annotation runx2_human recname: full=runt-related
transcription factor 2; altname:
full=acu te myeloid leukemia 3
protein; altname: full=core-binding
factor subu ...
Sequence Length 521

Dataset Information:

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Model Information

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Target Region101-224
Protein Length521
Template PDB Code1eaqA
Template Region50-173
Sequence Identity90%
E-Value0
GA3411
MPQS1.3919
z-DOPE-1.71
TSVMod MethodMTALL
TSVMod RMSD0.3
TSVMod NO350.991
Datasethuman_2010_A1
ModPipe VersionSVN.r1188:1193
Model Date2010-11-02

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1eaqan "s-switch" and chloride ions modulate the dna-binding ability of runx/aml1 ; PFAM: PF00853 ; SCOP: 76144
DBALI1eaqA 
CATH2.60.40.720 Domain: 1eaqA00 Immunoglobulin-like (100%)
JenaImageLibrary1eaq 
Target Sequence
UniProtKBO14615RecName: Full=Runt-related transcription factor 2;AltName: Full=Acute myeloid leukemia 3 protein;AltName: Full=Core-binding factor subunit alpha-1;Short=CBF-alpha-1;AltName: Full=Oncogene AML-3;AltNam
InterProO14615 
PFAMO14615 
ProdomO14615 
UniProtKBQ13950RecName: Full=Runt-related transcription factor 2;AltName: Full=Acute myeloid leukemia 3 protein;AltName: Full=Core-binding factor subunit alpha-1;Short=CBF-alpha-1;AltName: Full=Oncogene AML-3;AltNam
InterProQ13950 
PFAMQ13950 
ProdomQ13950 
UniProtKBO14614RecName: Full=Runt-related transcription factor 2;AltName: Full=Acute myeloid leukemia 3 protein;AltName: Full=Core-binding factor subunit alpha-1;Short=CBF-alpha-1;AltName: Full=Oncogene AML-3;AltNam
InterProO14614 
PFAMO14614 
ProdomO14614 
UniProtKBO95181RecName: Full=Runt-related transcription factor 2;AltName: Full=Acute myeloid leukemia 3 protein;AltName: Full=Core-binding factor subunit alpha-1;Short=CBF-alpha-1;AltName: Full=Oncogene AML-3;AltNam
InterProO95181 
PFAMO95181 
ProdomO95181 
UniProtKBA0A2J8Y4Y3Runt-related transcription factor {ECO:0000256|PIRNR:PIRNR009374}
InterProA0A2J8Y4Y3 
PFAMA0A2J8Y4Y3 
ProdomA0A2J8Y4Y3 
UniProtKBO14614CORE BINDING FACTOR ALPHA1 SUBUNIT (CBFA1/OSF2 TRANSCRIPTION FACTOR)
InterProO14614 
PFAMO14614 
ProdomO14614 
UniProtKBO95181RecName: Full=Runt-related transcription factor 2;AltName: Full=Acute myeloid leukemia 3 protein;AltName: Full=Core-binding factor subunit alpha-1;Short=CBF-alpha-1;AltName: Full=Oncogene AML-3;AltNam
InterProO95181 
PFAMO95181 
ProdomO95181 
UniProtKBO14615RecName: Full=Runt-related transcription factor 2;AltName: Full=Acute myeloid leukemia 3 protein;AltName: Full=Core-binding factor subunit alpha-1;Short=CBF-alpha-1;AltName: Full=Oncogene AML-3;AltNam
InterProO14615 
PFAMO14615 
ProdomO14615 
UniProtKBQ13950RecName: Full=Runt-related transcription factor 2;AltName: Full=Acute myeloid leukemia 3 protein;AltName: Full=Core-binding factor subunit alpha-1;Short=CBF-alpha-1;AltName: Full=Oncogene AML-3;AltNam
InterProQ13950 
PFAMQ13950 
ProdomQ13950 
UniProtKBO14614RecName: Full=Runt-related transcription factor 2;AltName: Full=Acute myeloid leukemia 3 protein;AltName: Full=Core-binding factor subunit alpha-1;Short=CBF-alpha-1;AltName: Full=Oncogene AML-3;AltNam
InterProO14614 
PFAMO14614 
ProdomO14614 
UniProtKBQ13950.2RUNX2_HUMAN RecName: Full=Runt-related transcription factor 2; AltName: Full=Acute myeloid leukemia 3 protein; AltName: Full=Core-binding factor subunit alpha-1; Short=CBF-alpha-1; AltName: Full=Oncog
InterProQ13950.2 
PFAMQ13950.2 
ProdomQ13950.2 
RefSeqNP_001019801.3 runt-related transcription factor 2 isoform a [Homo sapiens]
GenPept17368460RUNX2_HUMAN RecName: Full=Runt-related transcription factor 2; AltName: Full=Acute myeloid leukemia 3 protein; AltName: Full=Core-binding factor subunit alpha-1; Short=CBF-alpha-1; AltName: Full=Oncog
GenPept226442783 runt-related transcription factor 2 isoform a [Homo sapiens]
GenPept55959065runt-related transcription factor 2
GenPept56203977runt-related transcription factor 2
GenPept56205905runt-related transcription factor 2
GenPept5724787core binding factor alpha1 subunit
GenBankAAB65159.2 core binding factor alpha1 subunit [Homo sapiens]
EMBLCAI13531.1 
EMBLCAI19639.1 
EMBLCAI19931.1 
ENSEMBLENSP00000420707