University of California San Francisco | About UCSF | UCSF Benioff Children's Hospital San Francisco

ModBase: Database of Comparative Protein Structure Models

Model Details Page: SNP Information

Sequence Information

Primary Database Link A4D1G0
Original Database ID sp Q00534
Organism Cercocebus atys, Cercocebus torquatus atys, etc.
Annotation subname: full=cyclin-dependent
kinase 6;subname: full=hcg19542;subname:
full=cdn a, flj94044, homo sapiens
cyclin-dependent kinase 6 (cdk6),
mrna;
Sequence Length 326
 

SNP Information

Perform action on this model:

 
 
SNP ViewGenome
Browser		ResidueAA-Residue
Variants		InterfaceLigandStabilityValidated
rs28365040 K279 KMRT  

Sequence Model Coverage summary
for all models of this sequence

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3i6ustructure and activation mechanism of the chk2 dna-damage checkpoint kinase
DBALI3i6uA 
JenaImageLibrary3i6u 
Target Sequence
UniProtKBA4D1G0SubName: Full=Cyclin-dependent kinase 6;SubName: Full=HCG19542;SubName: Full=cDNA, FLJ94044, Homo sapiens cyclin-dependent kinase 6 (CDK6), mRNA;
InterProA4D1G0 
PFAMA4D1G0 
ProdomA4D1G0 
UniProtKBA0A0D9RJK6SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000008795};
InterProA0A0D9RJK6 
PFAMA0A0D9RJK6 
ProdomA0A0D9RJK6 
UniProtKBF7E5V8SubName: Full=Cyclin-dependent kinase 6 {ECO:0000313|EMBL:AFE63641.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000011403};
InterProF7E5V8 
PFAMF7E5V8 
ProdomF7E5V8 
UniProtKBG7P1D7SubName: Full=Putative uncharacterized protein {ECO:0000313|EMBL:EHH52346.1};
InterProG7P1D7 
PFAMG7P1D7 
ProdomG7P1D7 
UniProtKBH2PMX6SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000019970};
InterProH2PMX6 
PFAMH2PMX6 
ProdomH2PMX6 
UniProtKBH2QUX4SubName: Full=Cyclin-dependent kinase 6 {ECO:0000313|EMBL:JAA10407.1};SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000033192};
InterProH2QUX4 
PFAMH2QUX4 
ProdomH2QUX4 
UniProtKBQ00534RecName: Full=Cyclin-dependent kinase 6;EC=2.7.11.22;AltName: Full=Cell division protein kinase 6;AltName: Full=Serine/threonine-protein kinase PLSTIRE;
InterProQ00534 
PFAMQ00534 
ProdomQ00534 
UniProtKBA0A096NF27SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPANP00000011515};
InterProA0A096NF27 
PFAMA0A096NF27 
ProdomA0A096NF27 
UniProtKBA0A2K5U063Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5U063 
PFAMA0A2K5U063 
ProdomA0A2K5U063 
UniProtKBG7MLW4Protein kinase domain-containing protein {ECO:0000259|SMART:SM00220}
InterProG7MLW4 
PFAMG7MLW4 
ProdomG7MLW4 
UniProtKBF7E5V8SubName: Full=Cyclin-dependent kinase 6;SubName: Full=Uncharacterized protein;
InterProF7E5V8 
PFAMF7E5V8 
ProdomF7E5V8 
UniProtKBA0A2K6P4F4Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K6P4F4 
PFAMA0A2K6P4F4 
ProdomA0A2K6P4F4 
UniProtKBA0A6D2W6Z6SubName: Full=CDK6 isoform 1 {ECO:0000313|EMBL:PNI42034.1}SubName: Full=CDK6 isoform 3 {ECO:0000313|EMBL:PNI42035.1}
InterProA0A6D2W6Z6 
PFAMA0A6D2W6Z6 
ProdomA0A6D2W6Z6 
UniProtKBA0A6D2X0V6SubName: Full=CDK6 isoform 1 {ECO:0000313|EMBL:PNJ70068.1}SubName: Full=CDK6 isoform 3 {ECO:0000313|EMBL:PNJ70069.1}
InterProA0A6D2X0V6 
PFAMA0A6D2X0V6 
ProdomA0A6D2X0V6 
UniProtKBA0A2J8L443SubName: Full=Cyclin-dependent kinase 6 {ECO:0000313|EMBL:JAA10407.1, ECO:0000313|Ensembl:ENSPTRP00000033192}
InterProA0A2J8L443 
PFAMA0A2J8L443 
ProdomA0A2J8L443 
UniProtKBA0A8D2JV35SubName: Full=Cyclin dependent kinase 6 {ECO:0000313|Ensembl:ENSTGEP00000003131}
InterProA0A8D2JV35 
PFAMA0A8D2JV35 
ProdomA0A8D2JV35 
UniProtKBA0A8J8XB64Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A8J8XB64 
PFAMA0A8J8XB64 
ProdomA0A8J8XB64 
UniProtKBA0A8J8YT09Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A8J8YT09 
PFAMA0A8J8YT09 
ProdomA0A8J8YT09 
UniProtKBA4D1G0SubName: Full=Cyclin-dependent kinase 6;SubName: Full=HCG19542;SubName: Full=cDNA, FLJ94044, Homo sapiens cyclin-dependent kinase 6 (CDK6), mRNA;
InterProA4D1G0 
PFAMA4D1G0 
ProdomA4D1G0 
UniProtKBG7P1D7SubName: Full=Putative uncharacterized protein;
InterProG7P1D7 
PFAMG7P1D7 
ProdomG7P1D7 
UniProtKBA0A2J8WJX0SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000019970}
InterProA0A2J8WJX0 
PFAMA0A2J8WJX0 
ProdomA0A2J8WJX0 
UniProtKBA0A2K5ZCQ4Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5ZCQ4 
PFAMA0A2K5ZCQ4 
ProdomA0A2K5ZCQ4 
UniProtKBA0A2K6DGQ0Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K6DGQ0 
PFAMA0A2K6DGQ0 
ProdomA0A2K6DGQ0 
UniProtKBA0A2K6N2K9Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K6N2K9 
PFAMA0A2K6N2K9 
ProdomA0A2K6N2K9 
UniProtKBH9EMN3SubName: Full=Cyclin-dependent kinase 6 {ECO:0000313|EMBL:AFE63642.1, ECO:0000313|Ensembl:ENSMMUP00000065722}
InterProH9EMN3 
PFAMH9EMN3 
ProdomH9EMN3 
UniProtKBA0A2K5MIA8Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5MIA8 
PFAMA0A2K5MIA8 
ProdomA0A2K5MIA8 
UniProtKBH2QUX4SubName: Full=Uncharacterized protein;
InterProH2QUX4 
PFAMH2QUX4 
ProdomH2QUX4 
UniProtKBA0A2K5K1L5Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011}
InterProA0A2K5K1L5 
PFAMA0A2K5K1L5 
ProdomA0A2K5K1L5 
UniProtKBH2PMX6SubName: Full=Uncharacterized protein;
InterProH2PMX6 
PFAMH2PMX6 
ProdomH2PMX6 
UniProtKBA0A8C9I5S1SubName: Full=Cyclin dependent kinase 6 {ECO:0000313|Ensembl:ENSPTEP00000029406}
InterProA0A8C9I5S1 
PFAMA0A8C9I5S1 
ProdomA0A8C9I5S1 
UniProtKBQ00534RecName: Full=Cyclin-dependent kinase 6;EC=2.7.11.22;AltName: Full=Cell division protein kinase 6;AltName: Full=Serine/threonine-protein kinase PLSTIRE;
InterProQ00534 
PFAMQ00534 
ProdomQ00534 
UniProtKBQ00534.1CDK6_HUMAN RecName: Full=Cell division protein kinase 6; AltName: Full=Serine/threonine-protein kinase PLSTIRE
InterProQ00534.1 
PFAMQ00534.1 
ProdomQ00534.1 
UniProtKBA4D1G0RecName: Full=Cyclin-dependent kinase 6;EC=2.7.11.22;AltName: Full=Cell division protein kinase 6;AltName: Full=Serine/threonine-protein kinase PLSTIRE;
InterProA4D1G0 
PFAMA4D1G0 
ProdomA4D1G0 
RefSeqXP_002818258.1 PREDICTED: cell division protein kinase 6-like isoform 1 [Pongo abelii]
RefSeqXP_025234567.1cyclin-dependent kinase 6
RefSeqXP_023082497.1cyclin-dependent kinase 6
RefSeqXP_003809780.1cyclin-dependent kinase 6
RefSeqXP_003809779.1cyclin-dependent kinase 6
RefSeqXP_002818259.1 PREDICTED: cell division protein kinase 6-like isoform 2 [Pongo abelii]
RefSeqXP_001167181.1 PREDICTED: cyclin-dependent kinase 6 [Pan troglodytes]
RefSeqXP_001100307.1 PREDICTED: cell division protein kinase 6 [Macaca mulatta]
RefSeqXP_023082500.1cyclin-dependent kinase 6
RefSeqNP_001138778.1 cell division protein kinase 6 [Homo sapiens]
RefSeqXP_025234566.1cyclin-dependent kinase 6
RefSeqXP_030868876.1cyclin-dependent kinase 6
RefSeqXP_028700699.1cyclin-dependent kinase 6 isoform X1
RefSeqXP_023082501.1cyclin-dependent kinase 6
RefSeqXP_025234569.1cyclin-dependent kinase 6
RefSeqXP_030788205.1cyclin-dependent kinase 6
RefSeqXP_025234568.1cyclin-dependent kinase 6
RefSeqXP_023082499.1cyclin-dependent kinase 6
RefSeqNP_001250.1 cell division protein kinase 6 [Homo sapiens]
RefSeqXP_037860288.1cyclin-dependent kinase 6
RefSeqXP_033050286.1cyclin-dependent kinase 6
RefSeqXP_033050285.1cyclin-dependent kinase 6
RefSeqXP_033050289.1cyclin-dependent kinase 6
RefSeqXP_037860287.1cyclin-dependent kinase 6
RefSeqXP_033050287.1cyclin-dependent kinase 6
RefSeqXP_033050284.1cyclin-dependent kinase 6
PDB1BLXA Chain A, P19ink4dCDK6 COMPLEX
PDB1BLXAChain A, P19ink4dCDK6 COMPLEX
PDB1G3NEChain E, Structure Of A P18(Ink4c)-Cdk6-K-Cyclin Ternary Complex
PDB1G3NE Chain E, Structure Of A P18(Ink4c)-Cdk6-K-Cyclin Ternary Complex
PDB1G3NAChain A, Structure Of A P18(Ink4c)-Cdk6-K-Cyclin Ternary Complex
PDB1BI8CChain C, Mechanism Of G1 Cyclin Dependent Kinase Inhibition From The Structures Cdk6-P19ink4d Inhibitor Complex
PDB1BI8AChain A, Mechanism Of G1 Cyclin Dependent Kinase Inhibition From The Structures Cdk6-P19ink4d Inhibitor Complex
PDB1BI8C Chain C, Mechanism Of G1 Cyclin Dependent Kinase Inhibition From The Structures Cdk6-P19ink4d Inhibitor Complex
PDB4TTHBChain B, Crystal Structure Of A Cdk6/vcyclin Complex With Inhibitor Bound
PDB1BI7A Chain A, Mechanism Of G1 Cyclin Dependent Kinase Inhibition From The Structure Of The Cdk6-P16ink4a Tumor Suppressor Complex
PDB1BI7AChain A, Mechanism Of G1 Cyclin Dependent Kinase Inhibition From The Structure Of The Cdk6-P16ink4a Tumor Suppressor Complex
GenPept189069241unnamed protein product
GenPept21885467cyclin-dependent kinase 6
GenPept380783533cyclin-dependent kinase 6
GenPept107662S23387 protein kinase (EC 2.7.1.37) cdk6 - human
GenPept11422208 cyclin-dependent kinase 6 [Homo sapiens]
GenPept119597233hCG19542
GenPept13096719A Chain A, Structure Of A P18(Ink4c)-Cdk6-K-Cyclin Ternary Complex
GenPept13096722E Chain E, Structure Of A P18(Ink4c)-Cdk6-K-Cyclin Ternary Complex
GenPept223718134 cell division protein kinase 6 [Homo sapiens]
GenPept261860546cyclin-dependent kinase 6, partial
GenPept266423CDK6_HUMAN RecName: Full=Cell division protein kinase 6; AltName: Full=Serine/threonine-protein kinase PLSTIRE
GenPept51094901cyclin-dependent kinase 6
GenPept534486090Sequence 78 from patent US 8506948
GenPept53972225Sequence 1237 from patent US 6753314
GenPept568531998Sequence 14507 from patent US 8586006
GenPept61358532cyclin-dependent kinase 6
GenPept649099096CDK6, partial
GenPept649150793CDK6, partial
GenPept672886079B Chain B, Crystal Structure Of A Cdk6/vcyclin Complex With Inhibitor Bound
GenPept5107508A Chain A, P19ink4dCDK6 COMPLEX
GenPept60817303cyclin-dependent kinase 6
GenPept4502741 cell division protein kinase 6 [Homo sapiens]
GenPept297681083 PREDICTED: cell division protein kinase 6-like isoform 1 [Pongo abelii]
GenPept297681085 PREDICTED: cell division protein kinase 6-like isoform 2 [Pongo abelii]
GenPept30354472Cyclin-dependent kinase 6
GenPept355560832hypothetical protein EGK_13940
GenPept355747849hypothetical protein EGM_12775
GenPept36623serine/threonine protein kinase
GenPept380783531cyclin-dependent kinase 6
GenPept4389304A Chain A, Mechanism Of G1 Cyclin Dependent Kinase Inhibition From The Structure Of The Cdk6-P16ink4a Tumor Suppressor Complex
UCSCGenomeBrowserQ00534 
UCSCGenomeBrowserENSPTRT00000035908.1 
ENSEMBLENSP00000265734 
ENSEMBLENSPTRP00000033192 
ENSEMBLENSP00000265734TDI sequence
ENSEMBLENSP00000265734