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ModBase: Database of Comparative Protein Structure Models

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Sequence Information

Primary Database Link O95278
Original Database ID EN ENSP00000356489.3
Organism Homo sapiens
Annotation laforin (progressive myoclonus
epilepsy type 2)
Sequence Length 331

Dataset Information:

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Model Information

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Target Region157-321
Protein Length331
Template PDB Code2hcmA
Template Region11-145
Sequence Identity21%
E-Value0
GA3410.99
MPQS0.610589
z-DOPE-0.5
TSVMod MethodMTALL
TSVMod RMSD4.331
TSVMod NO350.683
DatasetTB_2hcmA_20091007-67864
ModPipe VersionSVN.r1278
Model Date2010-11-10

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in advanced pancreatic tumor for CCDS5206.1 R108C
Template Structure
PDB2hcmcrystal structure of mouse putative dual specificity phosphatase complexed with zinc tungstate, new york structural genomics consortium
DBALI2hcmA 
CATH3.90.190.10 Domain: 2hcmA01 Protein tyrosine phosphatase superfamily (91%)
JenaImageLibrary2hcm 
Target Sequence
UniProtKBQ9UEN2RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ9UEN2 
PFAMQ9UEN2 
ProdomQ9UEN2 
UniProtKBQ9BS66RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ9BS66 
PFAMQ9BS66 
ProdomQ9BS66 
UniProtKBQ8IX25RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ8IX25 
PFAMQ8IX25 
ProdomQ8IX25 
UniProtKBO95278LAFORIN (PROGRESSIVE MYOCLONUS epilepsy type 2)
InterProO95278 
PFAMO95278 
ProdomO95278 
UniProtKBQ5T3F5SubName: Full=Epilepsy, progressive myoclonus type 2A, Lafora disease (Laforin) (Epilepsy, progressive myoclonus type 2A, Lafora disease (Laforin), isoform CRA_b);
InterProQ5T3F5 
PFAMQ5T3F5 
ProdomQ5T3F5 
UniProtKBQ5THQ4Epilepsy, progressive myoclonus type 2A, Lafora disease (Laforin)(Epilepsy, progressive myoclonus type 2A, Lafora disease (Laforin),isoform CRA_b).
InterProQ5THQ4 
PFAMQ5THQ4 
ProdomQ5THQ4 
UniProtKBQ8IX24RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ8IX24 
PFAMQ8IX24 
ProdomQ8IX24 
UniProtKBQ9UEN2RecName: Full=Laforin;EC=3.1.3.-;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Glucan phosphatase;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ9UEN2 
PFAMQ9UEN2 
ProdomQ9UEN2 
UniProtKBO95278RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProO95278 
PFAMO95278 
ProdomO95278 
UniProtKBO95278.2EPM2A_HUMAN RecName: Full=Laforin; AltName: Full=Lafora PTPase; Short=LAFPTPase
InterProO95278.2 
PFAMO95278.2 
ProdomO95278.2 
UniProtKBO95483RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProO95483 
PFAMO95483 
ProdomO95483 
UniProtKBQ9BS66RecName: Full=Laforin;EC=3.1.3.-;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Glucan phosphatase;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ9BS66 
PFAMQ9BS66 
ProdomQ9BS66 
UniProtKBQ5T3F5RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ5T3F5 
PFAMQ5T3F5 
ProdomQ5T3F5 
UniProtKBQ8IX25RecName: Full=Laforin;EC=3.1.3.-;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Glucan phosphatase;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ8IX25 
PFAMQ8IX25 
ProdomQ8IX25 
UniProtKBQ8IU96RecName: Full=Laforin;EC=3.1.3.16;EC=3.1.3.48;AltName: Full=Lafora PTPase;Short=LAFPTPase;
InterProQ8IU96 
PFAMQ8IU96 
ProdomQ8IU96 
RefSeqNP_005661.1 laforin isoform a [Homo sapiens]
GenPept10505185AF284580_1 progressive myoclonus epilepsy type 2
GenPept56205604epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
GenPept50400258EPM2A_HUMAN RecName: Full=Laforin; AltName: Full=Lafora PTPase; Short=LAFPTPase
GenPept56202640epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
GenPept353304860Sequence 125 from patent US 8039210
GenPept56666740Sequence 2 from patent US 6825328
GenPept6005986laforin
GenPept757872457Sequence 2 from patent US 8486624
GenPept915840006Sequence 125 from patent US 9012145
GenPept259183746Sequence 2 from patent US 7550571
GenPept12731903 epilepsy, progressive myoclonus type 2, Lafora disease (laforin) [Homo sapiens]
GenPept119568229epilepsy, progressive myoclonus type 2A, Lafora disease (laforin), isoform CRA_b
GenPept11321613 laforin isoform a [Homo sapiens]
GenPept414902967Sequence 275 from patent US 8298775
GenBankEAW47844.1 epilepsy, progressive myoclonus type 2A, Lafora disease (laforin), isoform CRA_b [Homo sapiens]
GenBankAAC83347.2 laforin [Homo sapiens]
GenBankAAG18377.1AF284580_1 progressive myoclonus epilepsy type 2 [Homo sapiens]
ENSEMBLENSP00000262907Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase). [Homo sapiens]
EMBLCAI21419.1 
EMBLCAI21675.1 
UCSCGenomeBrowserO95278 
ENSEMBLENSP00000262907 
ENSEMBLENSP00000262907TDI sequence
ENSEMBLENSP00000356489