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Sequence Information

Primary Database Link P24181.2
Original Database ID ref NP_417732.1
Organism Escherichia coli, Escherichia coli K-12, etc.
Annotation acrf_ecoli recname: full=acriflavine
resistance protein f; altname:
full=protein envd
Sequence Length 1034

Dataset Information:

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Model Information

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Target Region1-1033
Protein Length1034
Template PDB Code2dhhA
Template Region1-1034
Sequence Identity78%
E-Value0
GA3411
MPQS1.84843
z-DOPE-0.14
TSVMod MethodMTALL
TSVMod RMSD2.89
TSVMod NO350.894
DatasetMW-e_coli_D1
ModPipe VersionSVN.r1602
Model Date2016-11-09

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Cross-references

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Template Structure
PDB2dhhcrystal structure of a multidrug transporter reveal a functionally rotating mechanism
DBALI2dhhA 
CATH1.20.1640.10 Domain: 2dhhA01 Multidrug efflux transporter AcrB transmembrane domain (100%)
CATH3.30.70.1430 Domain: 2dhhA02 Multidrug efflux transporter AcrB pore domain (100%)
CATH3.30.70.1320 Domain: 2dhhA03 Multidrug efflux transporter AcrB pore domain like (100%)
CATH3.30.2090.10 Domain: 2dhhA04 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains (100%)
CATH1.10.3850.10 Domain: 2dhhA05 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains (99%)
CATH3.30.70.1430 Domain: 2dhhA06 Multidrug efflux transporter AcrB pore domain (100%)
CATH3.30.70.1440 Domain: 2dhhA07 Multidrug efflux transporter AcrB pore domain (100%)
CATH3.30.2090.10 Domain: 2dhhA08 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains (100%)
JenaImageLibrary2dhh 
Target Sequence
UniProtKBL2Z0X4SubName: Full=Acriflavine resistance protein F;
InterProL2Z0X4 
PFAML2Z0X4 
ProdomL2Z0X4 
UniProtKBS0UMZ6SubName: Full=Acriflavine resistance protein F {ECO:0000313|EMBL:EOU56743.1};
InterProS0UMZ6 
PFAMS0UMZ6 
ProdomS0UMZ6 
UniProtKBS0XA41SubName: Full=Acriflavine resistance protein F;
InterProS0XA41 
PFAMS0XA41 
ProdomS0XA41 
UniProtKBA0A069XS93SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein {ECO:0000313|EMBL:KDU32780.1};
InterProA0A069XS93 
PFAMA0A069XS93 
ProdomA0A069XS93 
UniProtKBA0A069Z9V9SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein {ECO:0000313|EMBL:KDU54149.1};
InterProA0A069Z9V9 
PFAMA0A069Z9V9 
ProdomA0A069Z9V9 
UniProtKBA0A071C8L2SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein {ECO:0000313|EMBL:KDY87549.1};
InterProA0A071C8L2 
PFAMA0A071C8L2 
ProdomA0A071C8L2 
UniProtKBA0A071CBC7SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein {ECO:0000313|EMBL:KDZ16327.1};
InterProA0A071CBC7 
PFAMA0A071CBC7 
ProdomA0A071CBC7 
UniProtKBA0A071DCH5SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein {ECO:0000313|EMBL:KDZ39149.1};
InterProA0A071DCH5 
PFAMA0A071DCH5 
ProdomA0A071DCH5 
UniProtKBA0A073GNZ8SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein {ECO:0000313|EMBL:KEJ66522.1};
InterProA0A073GNZ8 
PFAMA0A073GNZ8 
ProdomA0A073GNZ8 
UniProtKBQ2M8U9RecName: Full=Acriflavine resistance protein F;AltName: Full=Protein EnvD;
InterProQ2M8U9 
PFAMQ2M8U9 
ProdomQ2M8U9 
UniProtKBT9ILX1SubName: Full=Multidrug efflux protein AcrB;
InterProT9ILX1 
PFAMT9ILX1 
ProdomT9ILX1 
UniProtKBL3QMD9SubName: Full=Acriflavine resistance protein F;
InterProL3QMD9 
PFAML3QMD9 
ProdomL3QMD9 
UniProtKBL3V733SubName: Full=Acriflavine resistance protein F;
InterProL3V733 
PFAML3V733 
ProdomL3V733 
UniProtKBL3WCQ2SubName: Full=Acriflavine resistance protein F;
InterProL3WCQ2 
PFAML3WCQ2 
ProdomL3WCQ2 
UniProtKBL4NT67SubName: Full=Acriflavine resistance protein F;
InterProL4NT67 
PFAML4NT67 
ProdomL4NT67 
UniProtKBN2ERX6SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProN2ERX6 
PFAMN2ERX6 
ProdomN2ERX6 
UniProtKBN2R851SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProN2R851 
PFAMN2R851 
ProdomN2R851 
UniProtKBT8ZH41SubName: Full=Multidrug efflux protein AcrB;
InterProT8ZH41 
PFAMT8ZH41 
ProdomT8ZH41 
UniProtKBP24181RecName: Full=Acriflavine resistance protein F;AltName: Full=Protein EnvD;
InterProP24181 
PFAMP24181 
ProdomP24181 
UniProtKBA0A073TIT1SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein {ECO:0000313|EMBL:KEL28258.1};
InterProA0A073TIT1 
PFAMA0A073TIT1 
ProdomA0A073TIT1 
UniProtKBA0A079GGD7SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein {ECO:0000313|EMBL:KDY86860.1};
InterProA0A079GGD7 
PFAMA0A079GGD7 
ProdomA0A079GGD7 
UniProtKBA0A094VEZ2SubName: Full=Acriflavine resistance protein B {ECO:0000313|EMBL:CEE06022.1};SubName: Full=Acriflavine resistance protein F {ECO:0000313|EMBL:KGM84006.1};SubName: Full=Multidrug export protein AcrF {E
InterProA0A094VEZ2 
PFAMA0A094VEZ2 
ProdomA0A094VEZ2 
UniProtKBC9QXK8SubName: Full=Multidrug efflux system protein;SubName: Full=Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family;Flags: Precursor;
InterProC9QXK8 
PFAMC9QXK8 
ProdomC9QXK8 
UniProtKBG2BEH1SubName: Full=Inner membrane protein;
InterProG2BEH1 
PFAMG2BEH1 
ProdomG2BEH1 
UniProtKBD8AIJ7SubName: Full=RND transporter, HAE1 family {ECO:0000313|EMBL:EFK17026.1};
InterProD8AIJ7 
PFAMD8AIJ7 
ProdomD8AIJ7 
UniProtKBD8B7S7SubName: Full=RND transporter, HAE1 family {ECO:0000313|EMBL:EFJ64854.1};
InterProD8B7S7 
PFAMD8B7S7 
ProdomD8B7S7 
UniProtKBD8C2K6SubName: Full=RND transporter, HAE1 family {ECO:0000313|EMBL:EFI86851.1};
InterProD8C2K6 
PFAMD8C2K6 
ProdomD8C2K6 
UniProtKBH4UPX7SubName: Full=Acriflavine resistance protein B {ECO:0000313|EMBL:EHV53752.1};
InterProH4UPX7 
PFAMH4UPX7 
ProdomH4UPX7 
UniProtKBH4V4L5SubName: Full=AcrB RND-type permease {ECO:0000313|EMBL:EHV54537.1};
InterProH4V4L5 
PFAMH4V4L5 
ProdomH4V4L5 
UniProtKBF9R386SubName: Full=Multidrug efflux system protein;
InterProF9R386 
PFAMF9R386 
ProdomF9R386 
UniProtKBC4ZT02SubName: Full=Multidrug efflux system protein;
InterProC4ZT02 
PFAMC4ZT02 
ProdomC4ZT02 
UniProtKBB1XHN5SubName: Full=Multidrug efflux system protein;
InterProB1XHN5 
PFAMB1XHN5 
ProdomB1XHN5 
UniProtKBA0A0E3MYZ7SubName: Full=Multidrug export protein AcrF {ECO:0000313|EMBL:AKA92452.1};
InterProA0A0E3MYZ7 
PFAMA0A0E3MYZ7 
ProdomA0A0E3MYZ7 
UniProtKBA0A0G3I4B5SubName: Full=Multidrug efflux system protein {ECO:0000313|EMBL:AKK19018.1};
InterProA0A0G3I4B5 
PFAMA0A0G3I4B5 
ProdomA0A0G3I4B5 
UniProtKBT9THI3SubName: Full=Multidrug efflux protein AcrB;
InterProT9THI3 
PFAMT9THI3 
ProdomT9THI3 
UniProtKBV1A7W0SubName: Full=Inner membrane multidrug efflux protein BpeB {ECO:0000313|EMBL:ESE02868.1};
InterProV1A7W0 
PFAMV1A7W0 
ProdomV1A7W0 
UniProtKBW1BUB0SubName: Full=RND efflux system, inner membrane transporter CmeB {ECO:0000313|EMBL:CDK83180.1};
InterProW1BUB0 
PFAMW1BUB0 
ProdomW1BUB0 
UniProtKBG2CR07SubName: Full=Inner membrane protein;
InterProG2CR07 
PFAMG2CR07 
ProdomG2CR07 
UniProtKBH0Q7Y8SubName: Full=Multidrug efflux system protein;
InterProH0Q7Y8 
PFAMH0Q7Y8 
ProdomH0Q7Y8 
UniProtKBT8SDR6SubName: Full=Multidrug efflux protein AcrB;
InterProT8SDR6 
PFAMT8SDR6 
ProdomT8SDR6 
UniProtKBG0F4B6SubName: Full=Inner membrane protein {ECO:0000313|EMBL:AEJ58667.1};
InterProG0F4B6 
PFAMG0F4B6 
ProdomG0F4B6 
UniProtKBK5GGZ9SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProK5GGZ9 
PFAMK5GGZ9 
ProdomK5GGZ9 
UniProtKBT9MIP1SubName: Full=Multidrug efflux protein AcrB;
InterProT9MIP1 
PFAMT9MIP1 
ProdomT9MIP1 
UniProtKBK5GQ05SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProK5GQ05 
PFAMK5GQ05 
ProdomK5GQ05 
UniProtKBI2YPW1SubName: Full=RND transporter, HAE1 family;
InterProI2YPW1 
PFAMI2YPW1 
ProdomI2YPW1 
UniProtKBI2X5U4SubName: Full=RND transporter, HAE1 family {ECO:0000313|EMBL:EII44364.1};
InterProI2X5U4 
PFAMI2X5U4 
ProdomI2X5U4 
UniProtKBH4W234SubName: Full=Acriflavine resistance protein B;
InterProH4W234 
PFAMH4W234 
ProdomH4W234 
UniProtKBS1L8U0SubName: Full=Acriflavine resistance protein F;
InterProS1L8U0 
PFAMS1L8U0 
ProdomS1L8U0 
UniProtKBT9M662SubName: Full=Multidrug efflux protein AcrB;
InterProT9M662 
PFAMT9M662 
ProdomT9M662 
UniProtKBS1CMD7SubName: Full=Acriflavine resistance protein F;
InterProS1CMD7 
PFAMS1CMD7 
ProdomS1CMD7 
UniProtKBM7VM85SubName: Full=Multidrug efflux system protein;
InterProM7VM85 
PFAMM7VM85 
ProdomM7VM85 
UniProtKBL3ZKM2SubName: Full=Acriflavine resistance protein F;
InterProL3ZKM2 
PFAML3ZKM2 
ProdomL3ZKM2 
UniProtKBK3J9D6SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProK3J9D6 
PFAMK3J9D6 
ProdomK3J9D6 
UniProtKBI2QYL2SubName: Full=Acriflavine resistance protein F;
InterProI2QYL2 
PFAMI2QYL2 
ProdomI2QYL2 
UniProtKBU0CTJ2SubName: Full=Multidrug efflux protein AcrB;
InterProU0CTJ2 
PFAMU0CTJ2 
ProdomU0CTJ2 
UniProtKBS1A0U9SubName: Full=Acriflavine resistance protein F;
InterProS1A0U9 
PFAMS1A0U9 
ProdomS1A0U9 
UniProtKBM2P2H9SubName: Full=Multidrug efflux system protein AcrF;
InterProM2P2H9 
PFAMM2P2H9 
ProdomM2P2H9 
UniProtKBI4J6S5SubName: Full=Acriflavine resistance protein F {ECO:0000313|EMBL:EIF84934.1};
InterProI4J6S5 
PFAMI4J6S5 
ProdomI4J6S5 
UniProtKBI2YA08SubName: Full=RND transporter, HAE1 family;
InterProI2YA08 
PFAMI2YA08 
ProdomI2YA08 
UniProtKBL8C4A5SubName: Full=RND efflux system, inner membrane transporter CmeB;
InterProL8C4A5 
PFAML8C4A5 
ProdomL8C4A5 
UniProtKBL3KD56SubName: Full=Acriflavine resistance protein F {ECO:0000313|EMBL:ELD96231.1};
InterProL3KD56 
PFAML3KD56 
ProdomL3KD56 
UniProtKBL4W8C9SubName: Full=Acriflavine resistance protein F;
InterProL4W8C9 
PFAML4W8C9 
ProdomL4W8C9 
UniProtKBT7KKI7SubName: Full=Multidrug efflux protein AcrB;
InterProT7KKI7 
PFAMT7KKI7 
ProdomT7KKI7 
UniProtKBT8ADV4SubName: Full=Multidrug efflux protein AcrB;
InterProT8ADV4 
PFAMT8ADV4 
ProdomT8ADV4 
UniProtKBU0CHI8SubName: Full=Multidrug efflux protein AcrB;
InterProU0CHI8 
PFAMU0CHI8 
ProdomU0CHI8 
UniProtKBH4WGD8SubName: Full=AcrB RND-type permease;
InterProH4WGD8 
PFAMH4WGD8 
ProdomH4WGD8 
UniProtKBI2PJA8SubName: Full=Acriflavine resistance protein F;
InterProI2PJA8 
PFAMI2PJA8 
ProdomI2PJA8 
UniProtKBI2ZTA9SubName: Full=RND transporter, HAE1 family;
InterProI2ZTA9 
PFAMI2ZTA9 
ProdomI2ZTA9 
UniProtKBI4U0R4SubName: Full=Multidrug efflux system protein;
InterProI4U0R4 
PFAMI4U0R4 
ProdomI4U0R4 
UniProtKBK3HTF7SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProK3HTF7 
PFAMK3HTF7 
ProdomK3HTF7 
UniProtKBS1KM43SubName: Full=Acriflavine resistance protein F;
InterProS1KM43 
PFAMS1KM43 
ProdomS1KM43 
UniProtKBS1JQY3SubName: Full=Acriflavine resistance protein F;
InterProS1JQY3 
PFAMS1JQY3 
ProdomS1JQY3 
UniProtKBN1SGA5SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProN1SGA5 
PFAMN1SGA5 
ProdomN1SGA5 
UniProtKBS0TJI8SubName: Full=Acriflavine resistance protein F;
InterProS0TJI8 
PFAMS0TJI8 
ProdomS0TJI8 
UniProtKBT8Y1P0SubName: Full=Multidrug efflux protein AcrB {ECO:0000313|EMBL:EQX49404.1};
InterProT8Y1P0 
PFAMT8Y1P0 
ProdomT8Y1P0 
UniProtKBD8AIJ7SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProD8AIJ7 
PFAMD8AIJ7 
ProdomD8AIJ7 
UniProtKBI2YA08SubName: Full=RND transporter, HAE1 family;
InterProI2YA08 
PFAMI2YA08 
ProdomI2YA08 
UniProtKBD8B7S7SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProD8B7S7 
PFAMD8B7S7 
ProdomD8B7S7 
UniProtKBI2YPW1SubName: Full=RND transporter, HAE1 family;
InterProI2YPW1 
PFAMI2YPW1 
ProdomI2YPW1 
UniProtKBD8C2K6SubName: Full=RND transporter, hydrophobe/amphiphile efflux-1 family protein;
InterProD8C2K6 
PFAMD8C2K6 
ProdomD8C2K6 
UniProtKBA0A8A5HQD5SubName: Full=Multidrug efflux RND transporter permease subunit AcrF {ECO:0000313|EMBL:QTF31520.1}
InterProA0A8A5HQD5 
PFAMA0A8A5HQD5 
ProdomA0A8A5HQD5 
UniProtKBH4V4L5SubName: Full=AcrB RND-type permease;
InterProH4V4L5 
PFAMH4V4L5 
ProdomH4V4L5 
UniProtKBI4U0R4SubName: Full=Multidrug efflux system protein;
InterProI4U0R4 
PFAMI4U0R4 
ProdomI4U0R4 
UniProtKBF9R386SubName: Full=Multidrug efflux system protein;
InterProF9R386 
PFAMF9R386 
ProdomF9R386 
UniProtKBI4J6S5SubName: Full=Acriflavine resistance protein F;
InterProI4J6S5 
PFAMI4J6S5 
ProdomI4J6S5 
UniProtKBG0F4B6SubName: Full=Inner membrane protein;
InterProG0F4B6 
PFAMG0F4B6 
ProdomG0F4B6 
UniProtKBI2X5U4SubName: Full=RND transporter, HAE1 family;
InterProI2X5U4 
PFAMI2X5U4 
ProdomI2X5U4 
UniProtKBI2QYL2SubName: Full=Acriflavine resistance protein F;
InterProI2QYL2 
PFAMI2QYL2 
ProdomI2QYL2 
UniProtKBA0A8F9I2U0SubName: Full=Multidrug efflux RND transporter permease subunit AcrF {ECO:0000313|EMBL:QYE39872.1}
InterProA0A8F9I2U0 
PFAMA0A8F9I2U0 
ProdomA0A8F9I2U0 
UniProtKBA0A8F9MS24SubName: Full=Multidrug efflux RND transporter permease subunit AcrF {ECO:0000313|EMBL:QYE26161.1}
InterProA0A8F9MS24 
PFAMA0A8F9MS24 
ProdomA0A8F9MS24 
UniProtKBG2CR07SubName: Full=Inner membrane protein;
InterProG2CR07 
PFAMG2CR07 
ProdomG2CR07 
UniProtKBH4UPX7SubName: Full=Acriflavine resistance protein B;
InterProH4UPX7 
PFAMH4UPX7 
ProdomH4UPX7 
UniProtKBH0Q7Y8SubName: Full=Multidrug efflux system protein;
InterProH0Q7Y8 
PFAMH0Q7Y8 
ProdomH0Q7Y8 
UniProtKBA0A8F8DGJ8SubName: Full=Multidrug efflux RND transporter permease subunit AcrF {ECO:0000313|EMBL:QXZ37383.1}
InterProA0A8F8DGJ8 
PFAMA0A8F8DGJ8 
ProdomA0A8F8DGJ8 
UniProtKBB1XHN5SubName: Full=Multidrug efflux system protein;
InterProB1XHN5 
PFAMB1XHN5 
ProdomB1XHN5 
UniProtKBC4ZT02SubName: Full=Multidrug efflux system protein;
InterProC4ZT02 
PFAMC4ZT02 
ProdomC4ZT02 
UniProtKBI2PJA8SubName: Full=Acriflavine resistance protein F;
InterProI2PJA8 
PFAMI2PJA8 
ProdomI2PJA8 
UniProtKBC9QXK8SubName: Full=Multidrug efflux system protein;SubName: Full=Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family;Flags: Precursor;
InterProC9QXK8 
PFAMC9QXK8 
ProdomC9QXK8 
UniProtKBQ2M8U9Multidrug efflux system protein
InterProQ2M8U9 
PFAMQ2M8U9 
ProdomQ2M8U9 
UniProtKBG2BEH1SubName: Full=Inner membrane protein;
InterProG2BEH1 
PFAMG2BEH1 
ProdomG2BEH1