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Sequence Information

Primary Database Link Q5XLC2
Original Database ID EN ENSP00000373240.2
Organism Pan paniscus, Pan troglodytes, etc.
Annotation subname: full=6-phosphofructo-2-kinase/fructose-2,
6-biphosphatase 4 splice isof
orm 5;ec=2.7.1.105;ec=3.1.3.46;subname:
full=fructose-2,6-bisphosphat
...
Sequence Length 434

Dataset Information:

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  Template
PDB Code		 PDB
Segment		 PDB Comment CATH
coverage
or Link		 Dataset Seq
Ident		 E-value Model
Score		 Quality Modeled Segment
6hviA(1-446)CATHMW-Human_D156501
1k6mA(39-469)crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase3.40.50.300
3.40.50.1240		MW-Human_D157701
1bifA(37-468)6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase bifunctional enzyme complexed with atp-g-s and phosphate3.40.50.300
3.40.50.1240		MW-Human_D159601

Cross-references

Show obsolete/secondary identifiers
Mutation Data
PharmGKB   PharmGKB data available for PFKFB4
Target Sequence
UniProtKBQ5XLC2SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 splice isoform 5;EC=2.7.1.105;EC=3.1.3.46;SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;
InterProQ5XLC2 
PFAMQ5XLC2 
ProdomQ5XLC2 
UniProtKBA0A2R9C0X16-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2R9C0X1 
PFAMA0A2R9C0X1 
ProdomA0A2R9C0X1 
UniProtKBQ5XLC2SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 splice isoform 5;EC=2.7.1.105;EC=3.1.3.46;SubName: Full=Fructose-2,6-bisphosphatase;
InterProQ5XLC2 
PFAMQ5XLC2 
ProdomQ5XLC2 
UniProtKBA0A6D2W3586-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A6D2W358 
PFAMA0A6D2W358 
ProdomA0A6D2W358 
UniProtKBA0A2I3RFQ56-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2I3RFQ5 
PFAMA0A2I3RFQ5 
ProdomA0A2I3RFQ5 
UniProtKBA0A2J8P9W96-phosphofructo-2-kinase {ECO:0000256|ARBA:ARBA00018900}EC=2.7.1.105 {ECO:0000256|ARBA:ARBA00012130}EC=3.1.3.46 {ECO:0000256|ARBA:ARBA00013067}AltName: Full=Fructose-2,6-bisphosphatase {ECO:0000256|AR
InterProA0A2J8P9W9 
PFAMA0A2J8P9W9 
ProdomA0A2J8P9W9 
RefSeqXP_001158238.1 PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 isoform 5 [Pan troglodytes]
GenPept541120276-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 splice isoform 5
GenPept407103183Sequence 3 from patent US 8263378
GenPept314681617Sequence 3 from patent US 7829682
GenPept114586701 PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform 5 [Pan troglodytes]
GenBankAAV28719.1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 splice isoform 5 [Homo sapiens]
ENSEMBLENSP00000373240