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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link P42574
Original Database ID gi 2780971
Organism Homo sapiens
Annotation caspase-3 precursor (ec 3.4.22.-)
(casp-3) (apopain) (cysteinede
protease cpp3 2) (yama protein)
(cpp-32) (srebp cleavage activity
1)de (sca-1) [c ...
Sequence Length 277

Dataset Information:

The newest dataset for this sequence was created on 2006-06-16. If you think that a better template has been added to the template database since, you can start a new calculation.

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  Template
PDB Code		 PDB
Segment		 PDB Comment CATH
coverage
or Link		 Dataset Seq
Ident		 E-value Model
Score		 Quality Modeled Segment
2fp3A(158-444)crystal structure of the drosophila initiator caspase droncCATHsnp-human4254e-571
1nw9B(140-415)structure of caspase-9 in an inhibitory complex with xiap-bir33.40.50.1460snp-human4358e-601
1nmsA(34-277)caspase-3 tethered to irreversible inhibitor3.40.50.1460snp-human4993e-711

Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Target Sequence
UniProtKBP42574Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (CysteineDE protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1)DE (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subun
InterProP42574 
PFAMP42574 
ProdomP42574 
PDB1CP3BChain B, Crystal Structure Of The Complex Of Apopain With The Tetrapeptide Inhibitor Ace-Dvad-Fmc
PDB1CP3AChain A, Crystal Structure Of The Complex Of Apopain With The Tetrapeptide Inhibitor Ace-Dvad-Fmc
PDB1CP3B Chain B, Crystal Structure Of The Complex Of Apopain With The Tetrapeptide Inhibitor Ace-Dvad-Fmc
GenPept561666cysteine protease CPP32 isoform alpha
GenPept59719982Sequence 98 from patent US 6833248
GenPept40091896Sequence 12 from patent US 6610541
GenPept34601694Sequence 12 from patent US 6376226
GenPept33752638Sequence 30 from patent US 6586571
GenPept314514997Sequence 30 from patent US 7799901
GenPept29713367Sequence 5 from patent US 6512104
GenPept2780973B Chain B, Crystal Structure Of The Complex Of Apopain With The Tetrapeptide Inhibitor Ace-Dvad-Fmc
GenPept2780971A Chain A, Crystal Structure Of The Complex Of Apopain With The Tetrapeptide Inhibitor Ace-Dvad-Fmc
GenPept25899709unnamed protein product
GenPept21516689Sequence 30 from patent US 6399327
GenPept21509074Sequence 12 from patent US 6379950
GenPept14271056unnamed protein product
GenPept1169072ICE3_HUMAN APOPAIN PRECURSOR (CYSTEINE PROTEASE CPP32) (YAMA PROTEIN) (CPP-32) (CASPASE-3) (CASP-3) (SREBP CLEAVAGE ACTI
GenPept1082321A55315 cysteine proteinase (EC 3.4.22.-) CPP32 precursor - human
GenBankAAA65015.1 cysteine protease CPP32 isoform alpha [Homo sapiens]
UCSCGenomeBrowserP42574