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Sequence Information

Primary Database Link P09126.1
Original Database ID ref NP_418248.1
Organism Escherichia coli, Shigella sonnei, etc.
Annotation hem4_ecoli recname: full=uroporphyrinogen-iii
synthase; short=uros; altname:
ful l=hydroxymethylbilane hydrolyase
[cyclizing]; altname: full=uroporphy
...
Sequence Length 246

Dataset Information:

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Model Information

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Target Region1-245
Protein Length246
Template PDB Code3mw8A
Template Region1-237
Sequence Identity37%
E-Value0
GA3411
MPQS1.47324
z-DOPE-0.54
TSVMod MethodMSALL
TSVMod RMSD2.948
TSVMod NO350.837
DatasetMW-e_coli_D1
ModPipe VersionSVN.r1602
Model Date2016-11-09

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Cross-references

Show obsolete/secondary identifiers
Template Structure
PDB3mw8crystal structure of an uroporphyrinogen-iii synthase (sama_3255) from shewanella amazonensis sb2b at 1.65 a resolution
DBALI3mw8A 
JenaImageLibrary3mw8 
Target Sequence
UniProtKBK5H945SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProK5H945 
PFAMK5H945 
ProdomK5H945 
UniProtKBA0A071CFD6SubName: Full=Uroporphyrinogen-III synthase HemD family protein {ECO:0000313|EMBL:KDZ17779.1};
InterProA0A071CFD6 
PFAMA0A071CFD6 
ProdomA0A071CFD6 
UniProtKBA0A079H1J6SubName: Full=Uroporphyrinogen-III synthase HemD family protein {ECO:0000313|EMBL:KDY97253.1};
InterProA0A079H1J6 
PFAMA0A079H1J6 
ProdomA0A079H1J6 
UniProtKBA0A080GHW2SubName: Full=Uroporphyrinogen-III synthase HemD family protein {ECO:0000313|EMBL:KEN86027.1};
InterProA0A080GHW2 
PFAMA0A080GHW2 
ProdomA0A080GHW2 
UniProtKBA0A094VWB0SubName: Full=Uroporphyrinogen III synthase {ECO:0000313|EMBL:KGM76585.1};EC=4.2.1.75 {ECO:0000313|EMBL:KGM76585.1};SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:AJB53817.1};EC=4.2.1.7
InterProA0A094VWB0 
PFAMA0A094VWB0 
ProdomA0A094VWB0 
UniProtKBA0A0A0F8Q5SubName: Full=Uroporphyrinogen III synthase {ECO:0000313|EMBL:KGM58815.1};EC=4.2.1.75 {ECO:0000313|EMBL:KGM58815.1};
InterProA0A0A0F8Q5 
PFAMA0A0A0F8Q5 
ProdomA0A0A0F8Q5 
UniProtKBA0A0E3N2D2SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:AKA92992.1};EC=4.2.1.75 {ECO:0000313|EMBL:AKA92992.1};
InterProA0A0E3N2D2 
PFAMA0A0E3N2D2 
ProdomA0A0E3N2D2 
UniProtKBA0A0G3HM95SubName: Full=Uroporphyrinogen III synthase protein {ECO:0000313|EMBL:AKK14469.1};
InterProA0A0G3HM95 
PFAMA0A0G3HM95 
ProdomA0A0G3HM95 
UniProtKBN2KNZ6SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProN2KNZ6 
PFAMN2KNZ6 
ProdomN2KNZ6 
UniProtKBN2R6F1SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProN2R6F1 
PFAMN2R6F1 
ProdomN2R6F1 
UniProtKBA0A071CB73SubName: Full=Uroporphyrinogen-III synthase HemD family protein {ECO:0000313|EMBL:KDY89281.1};
InterProA0A071CB73 
PFAMA0A071CB73 
ProdomA0A071CB73 
UniProtKBA0A070Y0G8SubName: Full=Uroporphyrinogen-III synthase HemD family protein {ECO:0000313|EMBL:KDX85077.1};
InterProA0A070Y0G8 
PFAMA0A070Y0G8 
ProdomA0A070Y0G8 
UniProtKBA0A069XHB6SubName: Full=Uroporphyrinogen-III synthase HemD family protein {ECO:0000313|EMBL:KDU29461.1};
InterProA0A069XHB6 
PFAMA0A069XHB6 
ProdomA0A069XHB6 
UniProtKBL3I313SubName: Full=Uroporphyrinogen-III synthase;
InterProL3I313 
PFAML3I313 
ProdomL3I313 
UniProtKBL3KAX4SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:ELD95258.1};
InterProL3KAX4 
PFAML3KAX4 
ProdomL3KAX4 
UniProtKBL3QLP6SubName: Full=Uroporphyrinogen-III synthase;
InterProL3QLP6 
PFAML3QLP6 
ProdomL3QLP6 
UniProtKBL3V4D2SubName: Full=Uroporphyrinogen-III synthase;
InterProL3V4D2 
PFAML3V4D2 
ProdomL3V4D2 
UniProtKBL3WAB7SubName: Full=Uroporphyrinogen-III synthase;
InterProL3WAB7 
PFAML3WAB7 
ProdomL3WAB7 
UniProtKBL3ZHX7SubName: Full=Uroporphyrinogen-III synthase;
InterProL3ZHX7 
PFAML3ZHX7 
ProdomL3ZHX7 
UniProtKBL4PSG3SubName: Full=Uroporphyrinogen-III synthase;
InterProL4PSG3 
PFAML4PSG3 
ProdomL4PSG3 
UniProtKBM7V8T6SubName: Full=Uroporphyrinogen III synthase;
InterProM7V8T6 
PFAMM7V8T6 
ProdomM7V8T6 
UniProtKBM7VBB8SubName: Full=Uroporphyrinogen III synthase;
InterProM7VBB8 
PFAMM7VBB8 
ProdomM7VBB8 
UniProtKBP09126RecName: Full=Uroporphyrinogen-III synthase;Short=UROS;EC=4.2.1.75;AltName: Full=Hydroxymethylbilane hydrolyase [cyclizing];AltName: Full=Uroporphyrinogen-III cosynthase;
InterProP09126 
PFAMP09126 
ProdomP09126 
UniProtKBQ2M8A9RecName: Full=Uroporphyrinogen-III synthase;Short=UROS;EC=4.2.1.75;AltName: Full=Hydroxymethylbilane hydrolyase [cyclizing];AltName: Full=Uroporphyrinogen-III cosynthase;
InterProQ2M8A9 
PFAMQ2M8A9 
ProdomQ2M8A9 
UniProtKBS1CSS8SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EOV53017.1};
InterProS1CSS8 
PFAMS1CSS8 
ProdomS1CSS8 
UniProtKBM8Q902SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProM8Q902 
PFAMM8Q902 
ProdomM8Q902 
UniProtKBV1AJ30SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:ESE06818.1};
InterProV1AJ30 
PFAMV1AJ30 
ProdomV1AJ30 
UniProtKBB1XAH1SubName: Full=Uroporphyrinogen III synthase;
InterProB1XAH1 
PFAMB1XAH1 
ProdomB1XAH1 
UniProtKBC4ZZ68SubName: Full=Uroporphyrinogen III synthase;
InterProC4ZZ68 
PFAMC4ZZ68 
ProdomC4ZZ68 
UniProtKBC9QWE8SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProC9QWE8 
PFAMC9QWE8 
ProdomC9QWE8 
UniProtKBE9X1S4SubName: Full=Uroporphyrinogen-III synthase HemD;
InterProE9X1S4 
PFAME9X1S4 
ProdomE9X1S4 
UniProtKBD7YBS8SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EFJ94914.1};EC=4.2.1.75 {ECO:0000313|EMBL:EFJ94914.1};
InterProD7YBS8 
PFAMD7YBS8 
ProdomD7YBS8 
UniProtKBD8ASM5SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EFK13860.1};EC=4.2.1.75 {ECO:0000313|EMBL:EFK13860.1};
InterProD8ASM5 
PFAMD8ASM5 
ProdomD8ASM5 
UniProtKBD8AZR7SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EFJ67693.1};EC=4.2.1.75 {ECO:0000313|EMBL:EFJ67693.1};
InterProD8AZR7 
PFAMD8AZR7 
ProdomD8AZR7 
UniProtKBF9R1A1SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProF9R1A1 
PFAMF9R1A1 
ProdomF9R1A1 
UniProtKBT9LV34SubName: Full=Uroporphyrinogen-III synthase;
InterProT9LV34 
PFAMT9LV34 
ProdomT9LV34 
UniProtKBM9G6R5SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProM9G6R5 
PFAMM9G6R5 
ProdomM9G6R5 
UniProtKBS1EII4SubName: Full=Uroporphyrinogen-III synthase;
InterProS1EII4 
PFAMS1EII4 
ProdomS1EII4 
UniProtKBS1H133SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EOW01584.1};
InterProS1H133 
PFAMS1H133 
ProdomS1H133 
UniProtKBS1IHN9SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EOW27190.1};
InterProS1IHN9 
PFAMS1IHN9 
ProdomS1IHN9 
UniProtKBS1KAT0SubName: Full=Uroporphyrinogen-III synthase;
InterProS1KAT0 
PFAMS1KAT0 
ProdomS1KAT0 
UniProtKBS1KGC4SubName: Full=Uroporphyrinogen-III synthase;
InterProS1KGC4 
PFAMS1KGC4 
ProdomS1KGC4 
UniProtKBT7ZW80SubName: Full=Uroporphyrinogen-III synthase;
InterProT7ZW80 
PFAMT7ZW80 
ProdomT7ZW80 
UniProtKBT8M2F9SubName: Full=Uroporphyrinogen-III synthase;
InterProT8M2F9 
PFAMT8M2F9 
ProdomT8M2F9 
UniProtKBT9JZM3SubName: Full=Uroporphyrinogen-III synthase;
InterProT9JZM3 
PFAMT9JZM3 
ProdomT9JZM3 
UniProtKBF4SRK9SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EGI08444.1};
InterProF4SRK9 
PFAMF4SRK9 
ProdomF4SRK9 
UniProtKBE1HNR7SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EFK90462.1};EC=4.2.1.75 {ECO:0000313|EMBL:EFK90462.1};
InterProE1HNR7 
PFAME1HNR7 
ProdomE1HNR7 
UniProtKBT9NCT7SubName: Full=Uroporphyrinogen-III synthase;
InterProT9NCT7 
PFAMT9NCT7 
ProdomT9NCT7 
UniProtKBL8BVX6SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProL8BVX6 
PFAML8BVX6 
ProdomL8BVX6 
UniProtKBM8MAK3SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProM8MAK3 
PFAMM8MAK3 
ProdomM8MAK3 
UniProtKBG2B200SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProG2B200 
PFAMG2B200 
ProdomG2B200 
UniProtKBS1C0J9SubName: Full=Uroporphyrinogen-III synthase;
InterProS1C0J9 
PFAMS1C0J9 
ProdomS1C0J9 
UniProtKBS1LIH8SubName: Full=Uroporphyrinogen-III synthase;
InterProS1LIH8 
PFAMS1LIH8 
ProdomS1LIH8 
UniProtKBH4URI5SubName: Full=Uroporphyrinogen-III synthase HemD family protein {ECO:0000313|EMBL:EHV52265.1};
InterProH4URI5 
PFAMH4URI5 
ProdomH4URI5 
UniProtKBH4WI31SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProH4WI31 
PFAMH4WI31 
ProdomH4WI31 
UniProtKBI2PFK5SubName: Full=Uroporphyrinogen-III synthase;
InterProI2PFK5 
PFAMI2PFK5 
ProdomI2PFK5 
UniProtKBT8XUS1SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EQX47880.1};
InterProT8XUS1 
PFAMT8XUS1 
ProdomT8XUS1 
UniProtKBL3RVL9SubName: Full=Uroporphyrinogen-III synthase;
InterProL3RVL9 
PFAML3RVL9 
ProdomL3RVL9 
UniProtKBI4U5I6SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProI4U5I6 
PFAMI4U5I6 
ProdomI4U5I6 
UniProtKBU0CU26SubName: Full=Uroporphyrinogen-III synthase;
InterProU0CU26 
PFAMU0CU26 
ProdomU0CU26 
UniProtKBI4J578SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EIF84387.1};
InterProI4J578 
PFAMI4J578 
ProdomI4J578 
UniProtKBG0F7G1SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:AEJ59205.1};
InterProG0F7G1 
PFAMG0F7G1 
ProdomG0F7G1 
UniProtKBT9UMB2SubName: Full=Uroporphyrinogen-III synthase;
InterProT9UMB2 
PFAMT9UMB2 
ProdomT9UMB2 
UniProtKBL4W5A3SubName: Full=Uroporphyrinogen-III synthase;
InterProL4W5A3 
PFAML4W5A3 
ProdomL4W5A3 
UniProtKBN2HEI6SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProN2HEI6 
PFAMN2HEI6 
ProdomN2HEI6 
UniProtKBG2F611SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProG2F611 
PFAMG2F611 
ProdomG2F611 
UniProtKBH4W3R2SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProH4W3R2 
PFAMH4W3R2 
ProdomH4W3R2 
UniProtKBI2Y5I3SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProI2Y5I3 
PFAMI2Y5I3 
ProdomI2Y5I3 
UniProtKBK3J6M5SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProK3J6M5 
PFAMK3J6M5 
ProdomK3J6M5 
UniProtKBL3INX6SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:ELD75536.1};
InterProL3INX6 
PFAML3INX6 
ProdomL3INX6 
UniProtKBL3TGG0SubName: Full=Uroporphyrinogen-III synthase;
InterProL3TGG0 
PFAML3TGG0 
ProdomL3TGG0 
UniProtKBT9ISG3SubName: Full=Uroporphyrinogen-III synthase;
InterProT9ISG3 
PFAMT9ISG3 
ProdomT9ISG3 
UniProtKBH4V866SubName: Full=Uroporphyrinogen-III synthase HemD family protein {ECO:0000313|EMBL:EHV51967.1};
InterProH4V866 
PFAMH4V866 
ProdomH4V866 
UniProtKBT8YHA2SubName: Full=Uroporphyrinogen-III synthase;
InterProT8YHA2 
PFAMT8YHA2 
ProdomT8YHA2 
UniProtKBI2I1A0SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProI2I1A0 
PFAMI2I1A0 
ProdomI2I1A0 
UniProtKBW1BJF9SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:CDK80823.1};EC=4.2.1.75 {ECO:0000313|EMBL:CDK80823.1};
InterProW1BJF9 
PFAMW1BJF9 
ProdomW1BJF9 
UniProtKBI2QXK8SubName: Full=Uroporphyrinogen-III synthase;
InterProI2QXK8 
PFAMI2QXK8 
ProdomI2QXK8 
UniProtKBI2X4A5SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:EII43825.1};EC=4.2.1.75 {ECO:0000313|EMBL:EII43825.1};
InterProI2X4A5 
PFAMI2X4A5 
ProdomI2X4A5 
UniProtKBI2ZKT4SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProI2ZKT4 
PFAMI2ZKT4 
ProdomI2ZKT4 
UniProtKBS0ZPE4SubName: Full=Uroporphyrinogen-III synthase;
InterProS0ZPE4 
PFAMS0ZPE4 
ProdomS0ZPE4 
UniProtKBQ47250RecName: Full=Uroporphyrinogen-III synthase;Short=UROS;EC=4.2.1.75;AltName: Full=Hydroxymethylbilane hydrolyase [cyclizing];AltName: Full=Uroporphyrinogen-III cosynthase;
InterProQ47250 
PFAMQ47250 
ProdomQ47250 
UniProtKBH0QF40SubName: Full=Uroporphyrinogen III synthase;
InterProH0QF40 
PFAMH0QF40 
ProdomH0QF40 
UniProtKBM8M1U6SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProM8M1U6 
PFAMM8M1U6 
ProdomM8M1U6 
UniProtKBM2N669SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProM2N669 
PFAMM2N669 
ProdomM2N669 
UniProtKBL3WNB2SubName: Full=Uroporphyrinogen-III synthase;
InterProL3WNB2 
PFAML3WNB2 
ProdomL3WNB2 
UniProtKBM8MM54SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProM8MM54 
PFAMM8MM54 
ProdomM8MM54 
UniProtKBM8PHD3SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProM8PHD3 
PFAMM8PHD3 
ProdomM8PHD3 
UniProtKBN2EHW6SubName: Full=Uroporphyrinogen-III synthase HemD family protein;
InterProN2EHW6 
PFAMN2EHW6 
ProdomN2EHW6 
UniProtKBG2BG63SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProG2BG63 
PFAMG2BG63 
ProdomG2BG63 
UniProtKBG2CS48SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProG2CS48 
PFAMG2CS48 
ProdomG2CS48 
UniProtKBE1HNR7SubName: Full=Uroporphyrinogen-III synthase;
InterProE1HNR7 
PFAME1HNR7 
ProdomE1HNR7 
UniProtKBD8AZR7SubName: Full=Uroporphyrinogen-III synthase;
InterProD8AZR7 
PFAMD8AZR7 
ProdomD8AZR7 
UniProtKBI2X4A5SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProI2X4A5 
PFAMI2X4A5 
ProdomI2X4A5 
UniProtKBD8ASM5SubName: Full=Uroporphyrinogen-III synthase;
InterProD8ASM5 
PFAMD8ASM5 
ProdomD8ASM5 
UniProtKBI2Y5I3SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProI2Y5I3 
PFAMI2Y5I3 
ProdomI2Y5I3 
UniProtKBD7YBS8SubName: Full=Uroporphyrinogen-III synthase;
InterProD7YBS8 
PFAMD7YBS8 
ProdomD7YBS8 
UniProtKBI4J578SubName: Full=Uroporphyrinogen-III synthase;
InterProI4J578 
PFAMI4J578 
ProdomI4J578 
UniProtKBI4U5I6SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProI4U5I6 
PFAMI4U5I6 
ProdomI4U5I6 
UniProtKBC9QWE8SubName: Full=Uroporphyrinogen-III synthase;EC=4.2.1.75;
InterProC9QWE8 
PFAMC9QWE8 
ProdomC9QWE8 
UniProtKBE9X1S4SubName: Full=Uroporphyrinogen-III synthase HemD;
InterProE9X1S4 
PFAME9X1S4 
ProdomE9X1S4