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Sequence Information

Primary Database Link A0A024KS45
Original Database ID ref NP_417827.1
Organism Escherichia coli, Klebsiella pneumoniae, etc.
Annotation recname: full=siroheme synthase
{eco:0000256|hamap-rule:mf_01646};
Sequence Length 457

Dataset Information:

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Model Information

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Target Region1-457
Protein Length457
Template PDB Code1pjqA
Template Region1-457
Sequence Identity90%
E-Value0
GA3411
MPQS1.9923
z-DOPE-0.2
TSVMod MethodMSALL
TSVMod RMSD2.519
TSVMod NO350.925
DatasetMW-e_coli_D1
ModPipe VersionSVN.r1602
Model Date2016-11-09

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Cross-references

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Template Structure
PDB1pjqstructure and function of cysg, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
DBALI1pjqA 
CATH3.40.50.720 Domain: 1pjqA01 NAD(P)-binding Rossmann-like Domain (100%)
CATH3.30.160.110 Domain: 1pjqA02 Siroheme synthase; domain 2 (100%)
CATH1.10.8.210 Domain: 1pjqA03 multifunctional methyltransferase/dehydrogenase/ferrochelatase, domain 3 (100%)
CATH3.40.1010.10 Domain: 1pjqA04 Cobalt-precorrin-4 Transmethylase; Domain 1 (100%)
CATH3.30.950.10 Domain: 1pjqA05 Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 (100%)
JenaImageLibrary1pjq 
Target Sequence
UniProtKBE1INV4RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProE1INV4 
PFAME1INV4 
ProdomE1INV4 
UniProtKBA0A071ARP4RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A071ARP4 
PFAMA0A071ARP4 
ProdomA0A071ARP4 
UniProtKBA0A071CDV6RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A071CDV6 
PFAMA0A071CDV6 
ProdomA0A071CDV6 
UniProtKBA0A073FR52RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A073FR52 
PFAMA0A073FR52 
ProdomA0A073FR52 
UniProtKBA0A073GJ11RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A073GJ11 
PFAMA0A073GJ11 
ProdomA0A073GJ11 
UniProtKBA0A073TV64RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A073TV64 
PFAMA0A073TV64 
ProdomA0A073TV64 
UniProtKBA0A074HHI0RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A074HHI0 
PFAMA0A074HHI0 
ProdomA0A074HHI0 
UniProtKBA0A079G2P0RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A079G2P0 
PFAMA0A079G2P0 
ProdomA0A079G2P0 
UniProtKBA0A079HBL2RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A079HBL2 
PFAMA0A079HBL2 
ProdomA0A079HBL2 
UniProtKBA0A080EX42RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A080EX42 
PFAMA0A080EX42 
ProdomA0A080EX42 
UniProtKBA0A080FJP5RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A080FJP5 
PFAMA0A080FJP5 
ProdomA0A080FJP5 
UniProtKBA0A070T0B2RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A070T0B2 
PFAMA0A070T0B2 
ProdomA0A070T0B2 
UniProtKBA0A070FLD6RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A070FLD6 
PFAMA0A070FLD6 
ProdomA0A070FLD6 
UniProtKBA8A5H5RecName: Full=Siroheme synthase;Includes:RecName: Full=Uroporphyrinogen-III C-methyltransferase;Short=Urogen III methylase;EC=2.1.1.107;AltName: Full=SUMT;AltName: Full=Uroporphyrinogen III methylase;
InterProA8A5H5 
PFAMA8A5H5 
ProdomA8A5H5 
UniProtKBD8BW14RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD8BW14 
PFAMD8BW14 
ProdomD8BW14 
UniProtKBE3PLH6RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProE3PLH6 
PFAME3PLH6 
ProdomE3PLH6 
UniProtKBE6B0F9RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProE6B0F9 
PFAME6B0F9 
ProdomE6B0F9 
UniProtKBE6BIC0RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProE6BIC0 
PFAME6BIC0 
ProdomE6BIC0 
UniProtKBE2KLE2RecName: Full=Siroheme synthase;
InterProE2KLE2 
PFAME2KLE2 
ProdomE2KLE2 
UniProtKBE8IEI0RecName: Full=Siroheme synthase;
InterProE8IEI0 
PFAME8IEI0 
ProdomE8IEI0 
UniProtKBE8HLR2RecName: Full=Siroheme synthase;
InterProE8HLR2 
PFAME8HLR2 
ProdomE8HLR2 
UniProtKBE8J7G6RecName: Full=Siroheme synthase;
InterProE8J7G6 
PFAME8J7G6 
ProdomE8J7G6 
UniProtKBE8H7Q7RecName: Full=Siroheme synthase;
InterProE8H7Q7 
PFAME8H7Q7 
ProdomE8H7Q7 
UniProtKBC6EFK8SubName: Full=Uroporphyrin-III C-methyltransferase {ECO:0000313|EMBL:ACT27451.1};
InterProC6EFK8 
PFAMC6EFK8 
ProdomC6EFK8 
UniProtKBA0A0E0U456RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0E0U456 
PFAMA0A0E0U456 
ProdomA0A0E0U456 
UniProtKBA0A0E0XUR4RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0E0XUR4 
PFAMA0A0E0XUR4 
ProdomA0A0E0XUR4 
UniProtKBC4ZUM4RecName: Full=Siroheme synthase;Includes:RecName: Full=Uroporphyrinogen-III C-methyltransferase;Short=Urogen III methylase;EC=2.1.1.107;AltName: Full=SUMT;AltName: Full=Uroporphyrinogen III methylase;
InterProC4ZUM4 
PFAMC4ZUM4 
ProdomC4ZUM4 
UniProtKBB3XIU7RecName: Full=Siroheme synthase;
InterProB3XIU7 
PFAMB3XIU7 
ProdomB3XIU7 
UniProtKBB3A180RecName: Full=Siroheme synthase;
InterProB3A180 
PFAMB3A180 
ProdomB3A180 
UniProtKBB1IP96RecName: Full=Siroheme synthase;Includes:RecName: Full=Uroporphyrinogen-III C-methyltransferase;Short=Urogen III methylase;EC=2.1.1.107;AltName: Full=SUMT;AltName: Full=Uroporphyrinogen III methylase;
InterProB1IP96 
PFAMB1IP96 
ProdomB1IP96 
UniProtKBD3QTJ5RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD3QTJ5 
PFAMD3QTJ5 
ProdomD3QTJ5 
UniProtKBC8TXY5RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProC8TXY5 
PFAMC8TXY5 
ProdomC8TXY5 
UniProtKBD7ZX22RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD7ZX22 
PFAMD7ZX22 
ProdomD7ZX22 
UniProtKBD7ZAK1RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD7ZAK1 
PFAMD7ZAK1 
ProdomD7ZAK1 
UniProtKBD8B472RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD8B472 
PFAMD8B472 
ProdomD8B472 
UniProtKBE0J006RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProE0J006 
PFAME0J006 
ProdomE0J006 
UniProtKBB6ZTH8RecName: Full=Siroheme synthase;
InterProB6ZTH8 
PFAMB6ZTH8 
ProdomB6ZTH8 
UniProtKBB7L4P2RecName: Full=Siroheme synthase;Includes:RecName: Full=Uroporphyrinogen-III C-methyltransferase;Short=Urogen III methylase;EC=2.1.1.107;AltName: Full=SUMT;AltName: Full=Uroporphyrinogen III methylase;
InterProB7L4P2 
PFAMB7L4P2 
ProdomB7L4P2 
UniProtKBB3AFP9RecName: Full=Siroheme synthase;
InterProB3AFP9 
PFAMB3AFP9 
ProdomB3AFP9 
UniProtKBA0A0E2U465RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0E2U465 
PFAMA0A0E2U465 
ProdomA0A0E2U465 
UniProtKBA0A0E2U7C9RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0E2U7C9 
PFAMA0A0E2U7C9 
ProdomA0A0E2U7C9 
UniProtKBA0A0G3KCT7RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0G3KCT7 
PFAMA0A0G3KCT7 
ProdomA0A0G3KCT7 
UniProtKBA0A0H3Q202RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0H3Q202 
PFAMA0A0H3Q202 
ProdomA0A0H3Q202 
UniProtKBA0A0H4S3H0SubName: Full=Siroheme synthase {ECO:0000313|EMBL:AKP86341.1};
InterProA0A0H4S3H0 
PFAMA0A0H4S3H0 
ProdomA0A0H4S3H0 
UniProtKBA0A0J3YL55SubName: Full=Siroheme synthase {ECO:0000313|EMBL:KME66890.1};
InterProA0A0J3YL55 
PFAMA0A0J3YL55 
ProdomA0A0J3YL55 
UniProtKBB2NLH7RecName: Full=Siroheme synthase;
InterProB2NLH7 
PFAMB2NLH7 
ProdomB2NLH7 
UniProtKBB1X716RecName: Full=Siroheme synthase;Includes:RecName: Full=Uroporphyrinogen-III C-methyltransferase;Short=Urogen III methylase;EC=2.1.1.107;AltName: Full=SUMT;AltName: Full=Uroporphyrinogen III methylase;
InterProB1X716 
PFAMB1X716 
ProdomB1X716 
UniProtKBB3BQS4RecName: Full=Siroheme synthase;
InterProB3BQS4 
PFAMB3BQS4 
ProdomB3BQS4 
UniProtKBB3AW77RecName: Full=Siroheme synthase;
InterProB3AW77 
PFAMB3AW77 
ProdomB3AW77 
UniProtKBE1HMV6RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProE1HMV6 
PFAME1HMV6 
ProdomE1HMV6 
UniProtKBD8E8A0RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD8E8A0 
PFAMD8E8A0 
ProdomD8E8A0 
UniProtKBA0A024KS45RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A024KS45 
PFAMA0A024KS45 
ProdomA0A024KS45 
UniProtKBE8YDV0RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProE8YDV0 
PFAME8YDV0 
ProdomE8YDV0 
UniProtKBA0A069Z182RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A069Z182 
PFAMA0A069Z182 
ProdomA0A069Z182 
UniProtKBA0A071CMR6RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A071CMR6 
PFAMA0A071CMR6 
ProdomA0A071CMR6 
UniProtKBA0A079DLZ0RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A079DLZ0 
PFAMA0A079DLZ0 
ProdomA0A079DLZ0 
UniProtKBA0A080GMZ0RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A080GMZ0 
PFAMA0A080GMZ0 
ProdomA0A080GMZ0 
UniProtKBA0A0F6FD65RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0F6FD65 
PFAMA0A0F6FD65 
ProdomA0A0F6FD65 
UniProtKBB2PGT0RecName: Full=Siroheme synthase;
InterProB2PGT0 
PFAMB2PGT0 
ProdomB2PGT0 
UniProtKBB3WJM6RecName: Full=Siroheme synthase;
InterProB3WJM6 
PFAMB3WJM6 
ProdomB3WJM6 
UniProtKBC5W9U8SubName: Full=Uroporphyrin-III C-methyltransferase {ECO:0000313|EMBL:ACT27451.1};
InterProC5W9U8 
PFAMC5W9U8 
ProdomC5W9U8 
UniProtKBD7XWF5RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD7XWF5 
PFAMD7XWF5 
ProdomD7XWF5 
UniProtKBE7HR07RecName: Full=Siroheme synthase;
InterProE7HR07 
PFAME7HR07 
ProdomE7HR07 
UniProtKBE1J1R9RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProE1J1R9 
PFAME1J1R9 
ProdomE1J1R9 
UniProtKBD6JFU9RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD6JFU9 
PFAMD6JFU9 
ProdomD6JFU9 
UniProtKBA0A026V6K5RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A026V6K5 
PFAMA0A026V6K5 
ProdomA0A026V6K5 
UniProtKBD6I248RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD6I248 
PFAMD6I248 
ProdomD6I248 
UniProtKBA0A027YY62RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A027YY62 
PFAMA0A027YY62 
ProdomA0A027YY62 
UniProtKBA0A0E3N0Y7RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0E3N0Y7 
PFAMA0A0E3N0Y7 
ProdomA0A0E3N0Y7 
UniProtKBC9QWR4RecName: Full=Siroheme synthase;
InterProC9QWR4 
PFAMC9QWR4 
ProdomC9QWR4 
UniProtKBE2WX32RecName: Full=Siroheme synthase;
InterProE2WX32 
PFAME2WX32 
ProdomE2WX32 
UniProtKBA0A069XMW6RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A069XMW6 
PFAMA0A069XMW6 
ProdomA0A069XMW6 
UniProtKBA0A074HQ75RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A074HQ75 
PFAMA0A074HQ75 
ProdomA0A074HQ75 
UniProtKBA0A0F6C9W2RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0F6C9W2 
PFAMA0A0F6C9W2 
ProdomA0A0F6C9W2 
UniProtKBB3HZI1RecName: Full=Siroheme synthase;
InterProB3HZI1 
PFAMB3HZI1 
ProdomB3HZI1 
UniProtKBD7Y660RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD7Y660 
PFAMD7Y660 
ProdomD7Y660 
UniProtKBE2JVC9RecName: Full=Siroheme synthase;
InterProE2JVC9 
PFAME2JVC9 
ProdomE2JVC9 
UniProtKBA0A0G3HUM6RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0G3HUM6 
PFAMA0A0G3HUM6 
ProdomA0A0G3HUM6 
UniProtKBA0A0H3XA49SubName: Full=Siroheme synthase {ECO:0000313|EMBL:AKM36912.1};
InterProA0A0H3XA49 
PFAMA0A0H3XA49 
ProdomA0A0H3XA49 
UniProtKBB2PBX5RecName: Full=Siroheme synthase;
InterProB2PBX5 
PFAMB2PBX5 
ProdomB2PBX5 
UniProtKBB3BC93RecName: Full=Siroheme synthase;
InterProB3BC93 
PFAMB3BC93 
ProdomB3BC93 
UniProtKBB3HHB7RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProB3HHB7 
PFAMB3HHB7 
ProdomB3HHB7 
UniProtKBC1NEY8SubName: Full=Siroheme synthase;
InterProC1NEY8 
PFAMC1NEY8 
ProdomC1NEY8 
UniProtKBC3SQE2RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProC3SQE2 
PFAMC3SQE2 
ProdomC3SQE2 
UniProtKBB1LHG9RecName: Full=Siroheme synthase;Includes:RecName: Full=Uroporphyrinogen-III C-methyltransferase;Short=Urogen III methylase;EC=2.1.1.107;AltName: Full=SUMT;AltName: Full=Uroporphyrinogen III methylase;
InterProB1LHG9 
PFAMB1LHG9 
ProdomB1LHG9 
UniProtKBD6IEQ4RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD6IEQ4 
PFAMD6IEQ4 
ProdomD6IEQ4 
UniProtKBD8AIF3RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProD8AIF3 
PFAMD8AIF3 
ProdomD8AIF3 
UniProtKBA0A0E1M2K9RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0E1M2K9 
PFAMA0A0E1M2K9 
ProdomA0A0E1M2K9 
UniProtKBA0A0A0FHG5RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A0A0FHG5 
PFAMA0A0A0FHG5 
ProdomA0A0A0FHG5 
UniProtKBA0A080EDB3RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A080EDB3 
PFAMA0A080EDB3 
ProdomA0A080EDB3 
UniProtKBC6UFW8RecName: Full=Siroheme synthase;
InterProC6UFW8 
PFAMC6UFW8 
ProdomC6UFW8 
UniProtKBE7TRS7RecName: Full=Siroheme synthase;
InterProE7TRS7 
PFAME7TRS7 
ProdomE7TRS7 
UniProtKBE8I0D0RecName: Full=Siroheme synthase;
InterProE8I0D0 
PFAME8I0D0 
ProdomE8I0D0 
UniProtKBE2K8Z1RecName: Full=Siroheme synthase;
InterProE2K8Z1 
PFAME2K8Z1 
ProdomE2K8Z1 
UniProtKBA0A070DSG1RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A070DSG1 
PFAMA0A070DSG1 
ProdomA0A070DSG1 
UniProtKBA0A070YNA7RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A070YNA7 
PFAMA0A070YNA7 
ProdomA0A070YNA7 
UniProtKBA0A071DGB7RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A071DGB7 
PFAMA0A071DGB7 
ProdomA0A071DGB7 
UniProtKBA0A073GMM3RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A073GMM3 
PFAMA0A073GMM3 
ProdomA0A073GMM3 
UniProtKBA0A079FFB1RecName: Full=Siroheme synthase {ECO:0000256|HAMAP-Rule:MF_01646};
InterProA0A079FFB1 
PFAMA0A079FFB1 
ProdomA0A079FFB1 
UniProtKBC6UVE2RecName: Full=Siroheme synthase;
InterProC6UVE2 
PFAMC6UVE2 
ProdomC6UVE2