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Sequence Information

Primary Database Link B1IQY4.1
Original Database ID ref NP_416123.1
Organism Escherichia coli, Shigella boydii, etc.
Annotation folm_ecolc recname: full=dihydrofolate
reductase folm; short=dhfr
Sequence Length 240

Dataset Information:

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Model Information

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Target Region8-240
Protein Length240
Template PDB Code3gemA
Template Region7-236
Sequence Identity45%
E-Value0
GA3411
MPQS1.51893
z-DOPE-0.88
TSVMod MethodMTALL
TSVMod RMSD7.245
TSVMod NO350.675
DatasetMW-e_coli_D1
ModPipe VersionSVN.r1602
Model Date2016-11-09

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Cross-references

Show obsolete/secondary identifiers
Template Structure
PDB3gemcrystal structure of short-chain dehydrogenase from pseudomonas syringae
DBALI3gemA 
CATH3.40.50.720 Domain: 3gemA00 NAD(P)-binding Rossmann-like Domain (99%)
JenaImageLibrary3gem 
Target Sequence
UniProtKBB3BMU4SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB3BMU4 
PFAMB3BMU4 
ProdomB3BMU4 
UniProtKBA0A071AQ18SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDY64636.1};
InterProA0A071AQ18 
PFAMA0A071AQ18 
ProdomA0A071AQ18 
UniProtKBA0A071BWN5SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDY88022.1};
InterProA0A071BWN5 
PFAMA0A071BWN5 
ProdomA0A071BWN5 
UniProtKBA0A073GS78SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KEJ68623.1};
InterProA0A073GS78 
PFAMA0A073GS78 
ProdomA0A073GS78 
UniProtKBA0A073TGE2SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KEL26874.1};
InterProA0A073TGE2 
PFAMA0A073TGE2 
ProdomA0A073TGE2 
UniProtKBA0A079FBQ4SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDY54496.1};
InterProA0A079FBQ4 
PFAMA0A079FBQ4 
ProdomA0A079FBQ4 
UniProtKBA0A079FZQ9SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDY65673.1};
InterProA0A079FZQ9 
PFAMA0A079FZQ9 
ProdomA0A079FZQ9 
UniProtKBA0A080J2I9SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KEO34115.1};
InterProA0A080J2I9 
PFAMA0A080J2I9 
ProdomA0A080J2I9 
UniProtKBA0A090NDW4SubName: Full=Dihydrofolate reductase {ECO:0000313|EMBL:ESU78112.1};EC=1.5.1.3 {ECO:0000313|EMBL:ESU78112.1};
InterProA0A090NDW4 
PFAMA0A090NDW4 
ProdomA0A090NDW4 
UniProtKBA0A0E1LXN7SubName: Full=Dihydromonapterin reductase / dihydrofolate reductase isozyme, NADPH-dependent {ECO:0000313|EMBL:AJF56457.1};EC=1.5.1.3 {ECO:0000313|EMBL:AJF56457.1};
InterProA0A0E1LXN7 
PFAMA0A0E1LXN7 
ProdomA0A0E1LXN7 
UniProtKBA0A0E1T245SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family {ECO:0000313|EMBL:EDU65221.1};
InterProA0A0E1T245 
PFAMA0A0E1T245 
ProdomA0A0E1T245 
UniProtKBA0A070TLJ2SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDX30716.1};
InterProA0A070TLJ2 
PFAMA0A070TLJ2 
ProdomA0A070TLJ2 
UniProtKBA0A070SU72SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDX21226.1};
InterProA0A070SU72 
PFAMA0A070SU72 
ProdomA0A070SU72 
UniProtKBH4NNE1SubName: Full=Uncharacterized protein;
InterProH4NNE1 
PFAMH4NNE1 
ProdomH4NNE1 
UniProtKBB3B6X0SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB3B6X0 
PFAMB3B6X0 
ProdomB3B6X0 
UniProtKBB1IQY4RecName: Full=Dihydrofolate reductase FolM;Short=DHFR;EC=1.5.1.3;
InterProB1IQY4 
PFAMB1IQY4 
ProdomB1IQY4 
UniProtKBB3XAF2SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB3XAF2 
PFAMB3XAF2 
ProdomB3XAF2 
UniProtKBB2N111SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB2N111 
PFAMB2N111 
ProdomB2N111 
UniProtKBH4PKF4SubName: Full=Uncharacterized protein;
InterProH4PKF4 
PFAMH4PKF4 
ProdomH4PKF4 
UniProtKBH4R010SubName: Full=Uncharacterized protein;
InterProH4R010 
PFAMH4R010 
ProdomH4R010 
UniProtKBB2P8Y3SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB2P8Y3 
PFAMB2P8Y3 
ProdomB2P8Y3 
UniProtKBH4RFI6SubName: Full=Uncharacterized protein;
InterProH4RFI6 
PFAMH4RFI6 
ProdomH4RFI6 
UniProtKBB3ABU9SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB3ABU9 
PFAMB3ABU9 
ProdomB3ABU9 
UniProtKBB3AUE4SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB3AUE4 
PFAMB3AUE4 
ProdomB3AUE4 
UniProtKBA0A0F6F6U7SubName: Full=FolM Alternative dihydrofolate reductase 1 {ECO:0000313|EMBL:AJA26137.1};
InterProA0A0F6F6U7 
PFAMA0A0F6F6U7 
ProdomA0A0F6F6U7 
UniProtKBA0A0G3HHB9SubName: Full=Dihydromonapterin reductase, NADPH-dependent dihydrofolate reductase isozyme protein {ECO:0000313|EMBL:AKK12711.1};
InterProA0A0G3HHB9 
PFAMA0A0G3HHB9 
ProdomA0A0G3HHB9 
UniProtKBE9WXW4SubName: Full=Short chain dehydrogenase;
InterProE9WXW4 
PFAME9WXW4 
ProdomE9WXW4 
UniProtKBE8HV84SubName: Full=Dihydromonapterin reductase;
InterProE8HV84 
PFAME8HV84 
ProdomE8HV84 
UniProtKBE2KIQ4SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProE2KIQ4 
PFAME2KIQ4 
ProdomE2KIQ4 
UniProtKBB5Z442SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB5Z442 
PFAMB5Z442 
ProdomB5Z442 
UniProtKBF4TGF0SubName: Full=Dihydrofolate reductase isozyme {ECO:0000313|EMBL:EGI21168.1};
InterProF4TGF0 
PFAMF4TGF0 
ProdomF4TGF0 
UniProtKBF4M9Z7SubName: Full=Short chain dehydrogenase;
InterProF4M9Z7 
PFAMF4M9Z7 
ProdomF4M9Z7 
UniProtKBH0QD07SubName: Full=Dihydrofolate reductase isozyme;
InterProH0QD07 
PFAMH0QD07 
ProdomH0QD07 
UniProtKBG2EYA3SubName: Full=Dihydromonapterin reductase;
InterProG2EYA3 
PFAMG2EYA3 
ProdomG2EYA3 
UniProtKBH4LUE9SubName: Full=Uncharacterized protein;
InterProH4LUE9 
PFAMH4LUE9 
ProdomH4LUE9 
UniProtKBH4MSN1SubName: Full=Uncharacterized protein;
InterProH4MSN1 
PFAMH4MSN1 
ProdomH4MSN1 
UniProtKBE8ILQ6SubName: Full=Dihydromonapterin reductase;
InterProE8ILQ6 
PFAME8ILQ6 
ProdomE8ILQ6 
UniProtKBE8IZT3SubName: Full=Dihydromonapterin reductase;
InterProE8IZT3 
PFAME8IZT3 
ProdomE8IZT3 
UniProtKBE2KTZ4SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProE2KTZ4 
PFAME2KTZ4 
ProdomE2KTZ4 
UniProtKBC6EDP2SubName: Full=Short-chain dehydrogenase/reductase SDR {ECO:0000313|EMBL:ACT29084.1};
InterProC6EDP2 
PFAMC6EDP2 
ProdomC6EDP2 
UniProtKBC6UIE6SubName: Full=Short chain dehydrogenase;
InterProC6UIE6 
PFAMC6UIE6 
ProdomC6UIE6 
UniProtKBC4ZY69SubName: Full=Dihydrofolate reductase isozyme;
InterProC4ZY69 
PFAMC4ZY69 
ProdomC4ZY69 
UniProtKBD8AU99SubName: Full=Dihydrofolate reductase FolM {ECO:0000313|EMBL:EFK13281.1};EC=1.5.1.3 {ECO:0000313|EMBL:EFK13281.1};
InterProD8AU99 
PFAMD8AU99 
ProdomD8AU99 
UniProtKBD7ZY07SubName: Full=Dihydrofolate reductase FolM {ECO:0000313|EMBL:EFK24216.1};EC=1.5.1.3 {ECO:0000313|EMBL:EFK24216.1};
InterProD7ZY07 
PFAMD7ZY07 
ProdomD7ZY07 
UniProtKBE1HT49SubName: Full=Dihydrofolate reductase FolM {ECO:0000313|EMBL:EFK88902.1};EC=1.5.1.3 {ECO:0000313|EMBL:EFK88902.1};
InterProE1HT49 
PFAME1HT49 
ProdomE1HT49 
UniProtKBD6IAR8SubName: Full=Dihydrofolate reductase folM {ECO:0000313|EMBL:EFF05549.2};
InterProD6IAR8 
PFAMD6IAR8 
ProdomD6IAR8 
UniProtKBC3T972SubName: Full=Dihydrofolate reductase FolM {ECO:0000313|EMBL:KGM69894.1};EC=1.5.1.3 {ECO:0000313|EMBL:KGM69894.1};SubName: Full=Dihydrofolate reductase folM {ECO:0000313|EMBL:CEE04667.1};EC=1.5.1.3 {E
InterProC3T972 
PFAMC3T972 
ProdomC3T972 
UniProtKBE6AZW4SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:EFU99375.1};EC=1.-.-.- {ECO:0000313|EMBL:EFU99375.1};
InterProE6AZW4 
PFAME6AZW4 
ProdomE6AZW4 
UniProtKBE2XHI3SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:EFP68580.1};EC=1.-.-.- {ECO:0000313|EMBL:EFP68580.1};
InterProE2XHI3 
PFAME2XHI3 
ProdomE2XHI3 
UniProtKBH4N7A0SubName: Full=Uncharacterized protein;
InterProH4N7A0 
PFAMH4N7A0 
ProdomH4N7A0 
UniProtKBH4MAU1SubName: Full=Uncharacterized protein;
InterProH4MAU1 
PFAMH4MAU1 
ProdomH4MAU1 
UniProtKBA0A023YXS9SubName: Full=FolM Alternative dihydrofolate reductase 1 {ECO:0000313|EMBL:AHY70600.1};
InterProA0A023YXS9 
PFAMA0A023YXS9 
ProdomA0A023YXS9 
UniProtKBB1XF71SubName: Full=Dihydrofolate reductase isozyme;
InterProB1XF71 
PFAMB1XF71 
ProdomB1XF71 
UniProtKBA0A069XKT8SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDU29768.1};
InterProA0A069XKT8 
PFAMA0A069XKT8 
ProdomA0A069XKT8 
UniProtKBA0A071CRB7SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDZ17218.1};
InterProA0A071CRB7 
PFAMA0A071CRB7 
ProdomA0A071CRB7 
UniProtKBA0A080GSW5SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KEN90808.1};
InterProA0A080GSW5 
PFAMA0A080GSW5 
ProdomA0A080GSW5 
UniProtKBA0A0E3KMG4SubName: Full=Dihydrofolate reductase FolM {ECO:0000313|EMBL:AKA90628.1};EC=1.5.1.3 {ECO:0000313|EMBL:AKA90628.1};
InterProA0A0E3KMG4 
PFAMA0A0E3KMG4 
ProdomA0A0E3KMG4 
UniProtKBD3QTW3SubName: Full=Dihydrofolate reductase folM {ECO:0000313|EMBL:ADD56572.1};
InterProD3QTW3 
PFAMD3QTW3 
ProdomD3QTW3 
UniProtKBE2K3Y1SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProE2K3Y1 
PFAME2K3Y1 
ProdomE2K3Y1 
UniProtKBE8HFZ9SubName: Full=Dihydromonapterin reductase;
InterProE8HFZ9 
PFAME8HFZ9 
ProdomE8HFZ9 
UniProtKBE9XZ83SubName: Full=Short chain dehydrogenase;
InterProE9XZ83 
PFAME9XZ83 
ProdomE9XZ83 
UniProtKBG2C498SubName: Full=Short chain dehydrogenase family protein;EC=1.-.-.-;
InterProG2C498 
PFAMG2C498 
ProdomG2C498 
UniProtKBE9Y958SubName: Full=Short chain dehydrogenase {ECO:0000313|EMBL:EGB69042.1};
InterProE9Y958 
PFAME9Y958 
ProdomE9Y958 
UniProtKBG2B9K2SubName: Full=Short chain dehydrogenase family protein;EC=1.-.-.-;
InterProG2B9K2 
PFAMG2B9K2 
ProdomG2B9K2 
UniProtKBA0A025CPW5SubName: Full=Dihydromonapterin reductase {ECO:0000313|EMBL:EYV17737.1};
InterProA0A025CPW5 
PFAMA0A025CPW5 
ProdomA0A025CPW5 
UniProtKBG0F1N2SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:AEJ56628.1};
InterProG0F1N2 
PFAMG0F1N2 
ProdomG0F1N2 
UniProtKBA0A027YQF8SubName: Full=Dihydromonapterin reductase {ECO:0000313|EMBL:EZD88467.1};
InterProA0A027YQF8 
PFAMA0A027YQF8 
ProdomA0A027YQF8 
UniProtKBC5W4I0SubName: Full=Short-chain dehydrogenase/reductase SDR {ECO:0000313|EMBL:ACT29084.1};
InterProC5W4I0 
PFAMC5W4I0 
ProdomC5W4I0 
UniProtKBF4SJL1SubName: Full=Dihydrofolate reductase isozyme {ECO:0000313|EMBL:EGI11213.1};
InterProF4SJL1 
PFAMF4SJL1 
ProdomF4SJL1 
UniProtKBH4Q173SubName: Full=Uncharacterized protein;
InterProH4Q173 
PFAMH4Q173 
ProdomH4Q173 
UniProtKBA0A029LKP8SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:EZJ86285.1};
InterProA0A029LKP8 
PFAMA0A029LKP8 
ProdomA0A029LKP8 
UniProtKBA0A079GNC6SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDY93774.1};
InterProA0A079GNC6 
PFAMA0A079GNC6 
ProdomA0A079GNC6 
UniProtKBC9QUY0SubName: Full=Dihydrofolate reductase folM;SubName: Full=Short-chain dehydrogenase/reductase SDR;
InterProC9QUY0 
PFAMC9QUY0 
ProdomC9QUY0 
UniProtKBE8H277SubName: Full=Dihydromonapterin reductase;
InterProE8H277 
PFAME8H277 
ProdomE8H277 
UniProtKBG2CK66SubName: Full=Short chain dehydrogenase family protein;EC=1.-.-.-;
InterProG2CK66 
PFAMG2CK66 
ProdomG2CK66 
UniProtKBA8A0E8RecName: Full=Dihydrofolate reductase FolM;Short=DHFR;EC=1.5.1.3;
InterProA8A0E8 
PFAMA8A0E8 
ProdomA8A0E8 
UniProtKBF1XQV9SubName: Full=FolM Alternative dihydrofolate reductase 1;
InterProF1XQV9 
PFAMF1XQV9 
ProdomF1XQV9 
UniProtKBC6UV47SubName: Full=Dihydrofolate reductase isozyme;
InterProC6UV47 
PFAMC6UV47 
ProdomC6UV47 
UniProtKBD8B9Z0SubName: Full=Dihydrofolate reductase FolM {ECO:0000313|EMBL:EFJ64091.1};EC=1.5.1.3 {ECO:0000313|EMBL:EFJ64091.1};
InterProD8B9Z0 
PFAMD8B9Z0 
ProdomD8B9Z0 
UniProtKBD8C4W6SubName: Full=Dihydrofolate reductase FolM {ECO:0000313|EMBL:EFI86042.1};EC=1.5.1.3 {ECO:0000313|EMBL:EFI86042.1};
InterProD8C4W6 
PFAMD8C4W6 
ProdomD8C4W6 
UniProtKBE3PMI1SubName: Full=Putative short chain dehydrogenase {ECO:0000313|EMBL:CBJ01143.1};
InterProE3PMI1 
PFAME3PMI1 
ProdomE3PMI1 
UniProtKBE7TZ00SubName: Full=FolM Alternative dihydrofolate reductase 1;
InterProE7TZ00 
PFAME7TZ00 
ProdomE7TZ00 
UniProtKBE8J1K4SubName: Full=Dihydromonapterin reductase;
InterProE8J1K4 
PFAME8J1K4 
ProdomE8J1K4 
UniProtKBE9WEV6SubName: Full=Short chain dehydrogenase;
InterProE9WEV6 
PFAME9WEV6 
ProdomE9WEV6 
UniProtKBB7A2E6SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB7A2E6 
PFAMB7A2E6 
ProdomB7A2E6 
UniProtKBG2AUW5SubName: Full=Short chain dehydrogenase family protein;EC=1.-.-.-;
InterProG2AUW5 
PFAMG2AUW5 
ProdomG2AUW5 
UniProtKBH1E261SubName: Full=Dihydrofolate reductase folM;
InterProH1E261 
PFAMH1E261 
ProdomH1E261 
UniProtKBA0A0H3PJ08SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family {ECO:0000313|EMBL:EDU89370.1};
InterProA0A0H3PJ08 
PFAMA0A0H3PJ08 
ProdomA0A0H3PJ08 
UniProtKBA0A0F6C4P8SubName: Full=Short chain dehydrogenase {ECO:0000313|EMBL:AFJ29204.1};
InterProA0A0F6C4P8 
PFAMA0A0F6C4P8 
ProdomA0A0F6C4P8 
UniProtKBA0A0E0TZ82SubName: Full=Short chain dehydrogenase {ECO:0000313|EMBL:AEE56657.1};
InterProA0A0E0TZ82 
PFAMA0A0E0TZ82 
ProdomA0A0E0TZ82 
UniProtKBH4QIQ0SubName: Full=Uncharacterized protein;
InterProH4QIQ0 
PFAMH4QIQ0 
ProdomH4QIQ0 
UniProtKBB2NU55SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB2NU55 
PFAMB2NU55 
ProdomB2NU55 
UniProtKBB2PRL6SubName: Full=Oxidoreductase, short chain dehydrogenase/reductase family;
InterProB2PRL6 
PFAMB2PRL6 
ProdomB2PRL6 
UniProtKBH4P569SubName: Full=Uncharacterized protein;
InterProH4P569 
PFAMH4P569 
ProdomH4P569 
UniProtKBA0A069Z4Z2SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDU54690.1};
InterProA0A069Z4Z2 
PFAMA0A069Z4Z2 
ProdomA0A069Z4Z2 
UniProtKBA0A070Y1T8SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDX84414.1};
InterProA0A070Y1T8 
PFAMA0A070Y1T8 
ProdomA0A070Y1T8 
UniProtKBA0A071DFK3SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KDZ39952.1};
InterProA0A071DFK3 
PFAMA0A071DFK3 
ProdomA0A071DFK3 
UniProtKBA0A074HWU3SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KEN98925.1};
InterProA0A074HWU3 
PFAMA0A074HWU3 
ProdomA0A074HWU3 
UniProtKBA0A080I8T9SubName: Full=Short chain dehydrogenase family protein {ECO:0000313|EMBL:KEO24255.1};
InterProA0A080I8T9 
PFAMA0A080I8T9 
ProdomA0A080I8T9 
UniProtKBF1Y3G3SubName: Full=FolM Alternative dihydrofolate reductase 1;
InterProF1Y3G3 
PFAMF1Y3G3 
ProdomF1Y3G3