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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link P04626.1
Original Database ID sp P04626
Organism Homo sapiens, synthetic construct, etc.
Annotation erbb2_human recname: full=receptor
tyrosine-protein kinase erbb-2;
altname: full =metastatic lymph
node gene 19 protein; short=mln
19; altname: full=p ...
Sequence Length 1255

Dataset Information:

The newest dataset for this sequence was created on 2016-06-12. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region23-642
Protein Length1255
Template PDB Code3n85A
Template Region1-620
Sequence Identity100%
E-Value0
GA3411
MPQS1.58122
z-DOPE-0.34
TSVMod MethodMSALL
TSVMod RMSD35.356
TSVMod NO350.496
DatasetMW-Human_D11
ModPipe VersionSVN.r1600
Model Date2016-06-12

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3n85crystallographic trimer of her2 extracellular regions in complex with tryptophan-rich antibody fragment
DBALI3n85A 
JenaImageLibrary3n85 
Target Sequence
UniProtKBB2RZG3RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProB2RZG3 
PFAMB2RZG3 
ProdomB2RZG3 
UniProtKBP04626RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProP04626 
PFAMP04626 
ProdomP04626 
UniProtKBQ14256RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProQ14256 
PFAMQ14256 
ProdomQ14256 
UniProtKBB4DHN3RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProB4DHN3 
PFAMB4DHN3 
ProdomB4DHN3 
UniProtKBQ6LDV1RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProQ6LDV1 
PFAMQ6LDV1 
ProdomQ6LDV1 
UniProtKBX5DNK3RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00067536};EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00067536};Flags: Fragment;
InterProX5DNK3 
PFAMX5DNK3 
ProdomX5DNK3 
UniProtKBQ9UMK4RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProQ9UMK4 
PFAMQ9UMK4 
ProdomQ9UMK4 
UniProtKBB2RZG3SubName: Full=V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (Avian);SubName: Full=V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, ne
InterProB2RZG3 
PFAMB2RZG3 
ProdomB2RZG3 
UniProtKBX5D2V5RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProX5D2V5 
PFAMX5D2V5 
ProdomX5D2V5 
UniProtKBB4DHN3RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProB4DHN3 
PFAMB4DHN3 
ProdomB4DHN3 
UniProtKBB2RZG3RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProB2RZG3 
PFAMB2RZG3 
ProdomB2RZG3 
UniProtKBQ9UMK4RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProQ9UMK4 
PFAMQ9UMK4 
ProdomQ9UMK4 
UniProtKBP04626RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProP04626 
PFAMP04626 
ProdomP04626 
UniProtKBP04626.1ERBB2_HUMAN RecName: Full=Receptor tyrosine-protein kinase erbB-2; AltName: Full=Metastatic lymph node gene 19 protein; Short=MLN 19; AltName: Full=Proto-oncogene Neu; AltName: Full=Proto-oncogene c-E
InterProP04626.1 
PFAMP04626.1 
ProdomP04626.1 
UniProtKBQ14256RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProQ14256 
PFAMQ14256 
ProdomQ14256 
UniProtKBQ6LDV1RecName: Full=Receptor tyrosine-protein kinase erbB-2;EC=2.7.10.1;AltName: Full=Metastatic lymph node gene 19 protein;Short=MLN 19;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-
InterProQ6LDV1 
PFAMQ6LDV1 
ProdomQ6LDV1 
RefSeqNP_004439.2 receptor tyrosine-protein kinase erbB-2 isoform a [Homo sapiens]
1202345A1202345A gene c-erbB2
GenPept756726089Sequence 20 from patent US 8808997
GenPept756521755Sequence 153 from patent US 8741556
GenPept756372645Sequence 17 from patent US 8703714
GenPept756322233Sequence 112 from patent US 8680041
GenPept61354730v-erb-b2 erythroblastic leukemia viral oncogene-like 2
GenPept61354726v-erb-b2 erythroblastic leukemia viral oncogene-like 2
GenPept61354721v-erb-b2 erythroblastic leukemia viral oncogene-like 2
GenPept608785269v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2 isoform A, partial
GenPept5951013Sequence 2 from patent US 5869445
GenPept593006031Sequence 31 from patent US 8652466
GenPept568534551Sequence 22176 from patent US 8586006
GenPept568476356Sequence 23 from patent US 8580926
GenPept756734568Sequence 23 from patent US 8809290
GenPept756756347Sequence 553 from patent US 8815249
GenPept915673823Sequence 416 from patent US 8992932
GenPept915093302Sequence 1 from patent US 8945573
GenPept86984A24571 protein-tyrosine kinase (EC 2.7.1.112) erbB2 precursor - human
GenPept84660729unnamed protein product
GenPept83321268Sequence 2 from patent US 6953573
GenPept757036355Sequence 1 from patent US 8895017
GenPept757001734Sequence 1 from patent US 8883164
GenPept756957682Sequence 16 from patent US 8871211
GenPept756920369Sequence 45 from patent US 8858942
GenPept756900942Sequence 11 from patent US 8852604
GenPept756819569Sequence 24 from patent US 8829173
GenPept189862627Sequence 1 from patent US 7375091
GenPept119533ERBB2_HUMAN RecName: Full=Receptor tyrosine-protein kinase erbB-2; AltName: Full=Metastatic lymph node gene 19 protein; Short=MLN 19; AltName: Full=Proto-oncogene Neu; AltName: Full=Proto-oncogene c-E
GenPept217244920Sequence 1 from patent US 7446185
GenPept21899820unnamed protein product
GenPept228208097Sequence 17 from patent US 7498298
GenPept259179747Sequence 6 from patent US 7547681
GenPept2248741202345A gene c-erbB2
GenPept303074137Sequence 4 from patent US 7700299
GenPept31198unnamed protein product
GenPept314128637Sequence 1 from patent US 7737253
GenPept19577807unnamed protein product
GenPept155076304Sequence 17 from patent US 7202033
GenPept19575768unnamed protein product
GenPept119581001v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), isoform CRA_c
GenPept144963156Sequence 553 from patent US 7179645
GenPept15391667unnamed protein product
GenPept155070097Sequence 1 from patent US 7198920
GenPept155685160Sequence 1 from patent US 7229623
GenPept162319062V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
GenPept182991410Sequence 3 from patent US 7348010
GenPept187469647V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
GenPept314145121Sequence 17 from patent US 7745394
GenPept314265106Sequence 23 from patent US 7763438
GenPept550887078Sequence 17 from patent US 8557780
GenPept348048416Sequence 12 from patent US 8007810
GenPept383245382Sequence 17 from patent US 8142784
GenPept397017671Sequence 16 from patent US 8097256
GenPept430257245Sequence 11 from patent US 8323987
GenPept443883884Sequence 45 from patent US 8350011
GenPept448987646unnamed protein product
GenPept47971075unnamed protein product
GenPept53925466Sequence 6 from patent US 6734172
GenPept544080433Sequence 2 from patent US 8524491
GenPept344954800Sequence 17 from patent US 7994135
GenPept339439530Sequence 17 from patent US 7964567
GenPept339439495Sequence 17 from patent US 7964566
GenPept314536530Sequence 461 from patent US 7807392
GenPept314880836Sequence 1078 from patent US 7842467
GenPept314880840Sequence 1082 from patent US 7842467
GenPept331429105Sequence 2 from patent US 7884194
GenPept54792096 receptor tyrosine-protein kinase erbB-2 isoform a [Homo sapiens]
GenPept331467596Sequence 20 from patent US 7892760
GenPept336051256Sequence 17 from patent US 7947839
GenBankAAX41050.1 v-erb-b2 erythroblastic leukemia viral oncogene-like 2 [synthetic construct]
GenBankAAX41051.1 v-erb-b2 erythroblastic leukemia viral oncogene-like 2 [synthetic construct]
GenBankAAX41049.1 v-erb-b2 erythroblastic leukemia viral oncogene-like 2 [synthetic construct]
GenBankEAW60597.1 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), isoform CRA_c [Homo sapiens]
GenBankAAI56756.1 V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [synthetic construct]
GenBankAAI67147.1 V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [Homo sapiens]
ENSEMBLENSP00000269571Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.1.112) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19). [Homo sapiens]
EMBLCAA27060.1 
ENSEMBLENSP00000269571 
ENSEMBLENSP00000269571TDI sequence
ENSEMBLENSP00000269571 
UCSCGenomeBrowserP04626