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ModBase: Database of Comparative Protein Structure Models

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Sequence Information

Primary Database Link P06730.2
Original Database ID EN ENSP00000389624.2
Organism Macaca fascicularis, Macaca mulatta, etc.
Annotation if4e_human recname: full=eukaryotic
translation initiation factor
4e; short=eif- 4e; short=eif4e;
altname: full=eif-4f 25 kda subunit;
altname: full=m ...
Sequence Length 217

Dataset Information:

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Model Information

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Target Region1-217
Protein Length217
Template PDB Code2gpqA
Template Region1-217
Sequence Identity100%
E-Value0
GA3411
MPQS2.1174
z-DOPE-0.27
TSVMod MethodMTALL
TSVMod RMSD13.484
TSVMod NO350.907
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB2gpqcap-free structure of eif4e suggests basis for its allosteric regulation
DBALI2gpqA 
JenaImageLibrary2gpq 
Target Sequence
UniProtKBA0A0D9QVU1SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000000480};
InterProA0A0D9QVU1 
PFAMA0A0D9QVU1 
ProdomA0A0D9QVU1 
UniProtKBB7Z6V1RecName: Full=Eukaryotic translation initiation factor 4E;Short=eIF-4E;Short=eIF4E;AltName: Full=eIF-4F 25 kDa subunit;AltName: Full=mRNA cap-binding protein;
InterProB7Z6V1 
PFAMB7Z6V1 
ProdomB7Z6V1 
UniProtKBQ96E95RecName: Full=Eukaryotic translation initiation factor 4E;Short=eIF-4E;Short=eIF4E;AltName: Full=eIF-4F 25 kDa subunit;AltName: Full=mRNA cap-binding protein;
InterProQ96E95 
PFAMQ96E95 
ProdomQ96E95 
UniProtKBG2HH86SubName: Full=Eukaryotic translation initiation factor 4E {ECO:0000313|EMBL:BAK63094.1};
InterProG2HH86 
PFAMG2HH86 
ProdomG2HH86 
UniProtKBD6RCQ6RecName: Full=Eukaryotic translation initiation factor 4E;Short=eIF-4E;Short=eIF4E;AltName: Full=eIF-4F 25 kDa subunit;AltName: Full=mRNA cap-binding protein;
InterProD6RCQ6 
PFAMD6RCQ6 
ProdomD6RCQ6 
UniProtKBH9ENS9SubName: Full=Eukaryotic translation initiation factor 4E isoform 1 {ECO:0000313|EMBL:AFE64038.1};
InterProH9ENS9 
PFAMH9ENS9 
ProdomH9ENS9 
UniProtKBI7GAS4SubName: Full=Macaca fascicularis brain cDNA clone: QtrA-12942, similar to human eukaryotic translation initiation factor 4E (EIF4E), mRNA, RefSeq: NM_001968.1 {ECO:0000313|EMBL:BAE88752.1};
InterProI7GAS4 
PFAMI7GAS4 
ProdomI7GAS4 
UniProtKBP06730RecName: Full=Eukaryotic translation initiation factor 4E;Short=eIF-4E;Short=eIF4E;AltName: Full=eIF-4F 25 kDa subunit;AltName: Full=mRNA cap-binding protein;
InterProP06730 
PFAMP06730 
ProdomP06730 
UniProtKBA0A2K6M3I5SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSRBIP00000030337}
InterProA0A2K6M3I5 
PFAMA0A2K6M3I5 
ProdomA0A2K6M3I5 
UniProtKBA0A6D2XVG9SubName: Full=EIF4E isoform 1 {ECO:0000313|EMBL:PNI56566.1}
InterProA0A6D2XVG9 
PFAMA0A6D2XVG9 
ProdomA0A6D2XVG9 
UniProtKBA0A2K6AUV9SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMNEP00000002922}
InterProA0A2K6AUV9 
PFAMA0A2K6AUV9 
ProdomA0A2K6AUV9 
UniProtKBQ25L74Brain cDNA clone: QtrA-12942, similar to human eukaryotic translationDE initiation factor 4E (EIF4E),
InterProQ25L74 
PFAMQ25L74 
ProdomQ25L74 
UniProtKBA0A2J8TQQ5SubName: Full=EIF4E isoform 1 {ECO:0000313|EMBL:PNJ35350.1}
InterProA0A2J8TQQ5 
PFAMA0A2J8TQQ5 
ProdomA0A2J8TQQ5 
UniProtKBA0A2J8MAM5SubName: Full=Eukaryotic translation initiation factor 4E {ECO:0000313|EMBL:BAK63094.1, ECO:0000313|Ensembl:ENSPTRP00000062638}
InterProA0A2J8MAM5 
PFAMA0A2J8MAM5 
ProdomA0A2J8MAM5 
UniProtKBA0A2K6PUJ2SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSRROP00000020194}
InterProA0A2K6PUJ2 
PFAMA0A2K6PUJ2 
ProdomA0A2K6PUJ2 
UniProtKBG2HH86SubName: Full=Eukaryotic translation initiation factor 4E;
InterProG2HH86 
PFAMG2HH86 
ProdomG2HH86 
UniProtKBI7GAS4SubName: Full=Macaca fascicularis brain cDNA clone: QtrA-12942, similar to human eukaryotic translation initiation factor 4E (EIF4E), mRNA, RefSeq: NM_001968.1;
InterProI7GAS4 
PFAMI7GAS4 
ProdomI7GAS4 
UniProtKBH9ENS9SubName: Full=Eukaryotic translation initiation factor 4E isoform 1;
InterProH9ENS9 
PFAMH9ENS9 
ProdomH9ENS9 
UniProtKBA0A2K5JHE0SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCANP00000028293}
InterProA0A2K5JHE0 
PFAMA0A2K5JHE0 
ProdomA0A2K5JHE0 
UniProtKBD6RCQ6RecName: Full=Eukaryotic translation initiation factor 4E;Short=eIF-4E;Short=eIF4E;AltName: Full=eIF-4F 25 kDa subunit;AltName: Full=mRNA cap-binding protein;
InterProD6RCQ6 
PFAMD6RCQ6 
ProdomD6RCQ6 
UniProtKBQ96E95RecName: Full=Eukaryotic translation initiation factor 4E;Short=eIF-4E;Short=eIF4E;AltName: Full=eIF-4F 25 kDa subunit;AltName: Full=mRNA cap-binding protein;
InterProQ96E95 
PFAMQ96E95 
ProdomQ96E95 
UniProtKBP06730.2IF4E_HUMAN RecName: Full=Eukaryotic translation initiation factor 4E; Short=eIF-4E; Short=eIF4E; AltName: Full=eIF-4F 25 kDa subunit; AltName: Full=mRNA cap-binding protein
InterProP06730.2 
PFAMP06730.2 
ProdomP06730.2 
UniProtKBB7Z6V1RecName: Full=Eukaryotic translation initiation factor 4E;Short=eIF-4E;Short=eIF4E;AltName: Full=eIF-4F 25 kDa subunit;AltName: Full=mRNA cap-binding protein;
InterProB7Z6V1 
PFAMB7Z6V1 
ProdomB7Z6V1 
UniProtKBP06730RecName: Full=Eukaryotic translation initiation factor 4E;Short=eIF-4E;Short=eIF4E;AltName: Full=eIF-4F 25 kDa subunit;AltName: Full=mRNA cap-binding protein;
InterProP06730 
PFAMP06730 
ProdomP06730 
RefSeqXP_033064312.1eukaryotic translation initiation factor 4E
RefSeqXP_031991233.1eukaryotic translation initiation factor 4E isoform X3
RefSeqXP_033070761.1eukaryotic translation initiation factor 4E isoform X2
RefSeqXP_034796237.1eukaryotic translation initiation factor 4E
RefSeqXP_030675018.1eukaryotic translation initiation factor 4E isoform X3
RefSeqXP_001104976.1 PREDICTED: eukaryotic translation initiation factor 4E-like isoform 1 [Macaca mulatta]
RefSeqXP_018880568.2eukaryotic translation initiation factor 4E isoform X3
RefSeqXP_003829967.1eukaryotic translation initiation factor 4E isoform X3
RefSeqXP_024101818.1eukaryotic translation initiation factor 4E isoform X2
RefSeqXP_023046705.1eukaryotic translation initiation factor 4E
RefSeqNP_001959.1 eukaryotic translation initiation factor 4E isoform 1 [Homo sapiens]
PDB3SMUBChain B, Crystal Structure Of The Human Eif4e-4ebp1 Peptide Complex Without Cap
PDB3TF2AChain A, Crystal Structure Of The Cap Free Human Translation Initiation Factor Eif4e
PDB1IPCA Chain A, Crystal Structure Of Eukaryotic Initiation Factor 4e Complexed With 7-Methyl Gtp
PDB3TF2CChain C, Crystal Structure Of The Cap Free Human Translation Initiation Factor Eif4e
PDB3TF2DChain D, Crystal Structure Of The Cap Free Human Translation Initiation Factor Eif4e
PDB3U7XAChain A, Crystal Structure Of The Human Eif4e-4ebp1 Peptide Complex Without Cap
PDB3U7XBChain B, Crystal Structure Of The Human Eif4e-4ebp1 Peptide Complex Without Cap
PDB4AZAAChain A, Improved Eif4e Binding Peptides By Phage Display Guided Design.
PDB4AZACChain C, Improved Eif4e Binding Peptides By Phage Display Guided Design.
PDB4BEAAChain A, Crystal Structure Of Eif4e In Complex With A Stapled Peptide Derivative
PDB3SMUAChain A, Crystal Structure Of The Human Eif4e-4ebp1 Peptide Complex Without Cap
PDB2V8YAChain A, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
PDB2GPQAChain A, Cap-Free Structure Of Eif4e Suggests Basis For Its Allosteric Regulation
PDB2W97AChain A, Crystal Structure Of Eif4e Bound To Glycerol And Eif4g1 Peptide
PDB2V8WE Chain E, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
PDB2V8XE Chain E, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
PDB2W97A Chain A, Crystal Structure Of Eif4e Bound To Glycerol And Eif4g1 Peptide
PDB1IPCAChain A, Crystal Structure Of Eukaryotic Initiation Factor 4e Complexed With 7-methyl Gtp
PDB1IPBAChain A, Crystal Structure Of Eukaryotic Initiation Factor 4e Complexed With 7-methyl Gpppa
PDB1IPBA Chain A, Crystal Structure Of Eukaryotic Initiation Factor 4e Complexed With 7-Methyl Gpppa
PDB3TF2BChain B, Crystal Structure Of The Cap Free Human Translation Initiation Factor Eif4e
PDB2V8WAChain A, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
PDB2V8WEChain E, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
PDB2V8XAChain A, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
PDB2V8XEChain E, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
PDB2V8YE Chain E, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
PDB2V8YEChain E, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
PDB2GPQA Chain A, Cap-Free Structure Of Eif4e Suggests Basis For Its Allosteric Regulation
GenPept109075052 PREDICTED: eukaryotic translation initiation factor 4E-like isoform 1 [Macaca mulatta]
GenPept296175123unnamed protein product
GenPept119389606A Chain A, Cap-Free Structure Of Eif4e Suggests Basis For Its Allosteric Regulation
GenPept119626484eukaryotic translation initiation factor 4E, isoform CRA_c
GenPept158431105A Chain A, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
GenPept158431107E Chain E, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
GenPept158431109A Chain A, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
GenPept158431113A Chain A, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
GenPept158431115E Chain E, Crystallographic And Mass Spectrometric Characterisation Of Eif4e With N7-Cap Derivatives
GenPept21465626A Chain A, Crystal Structure Of Eukaryotic Initiation Factor 4e Complexed With 7-methyl Gpppa
GenPept261861246eukaryotic translation initiation factor 4E, partial
GenPept292659509A Chain A, Crystal Structure Of Eif4e Bound To Glycerol And Eif4g1 Peptide
GenPept345111039A Chain A, Crystal Structure Of The Cap Free Human Translation Initiation Factor Eif4e
GenPept60819169eukaryotic translation initiation factor 4E
GenPept407094876Sequence 1 from patent US 8257931
GenPept400260757C Chain C, Improved Eif4e Binding Peptides By Phage Display Guided Design.
GenPept400260755A Chain A, Improved Eif4e Binding Peptides By Phage Display Guided Design.
GenPept345111040B Chain B, Crystal Structure Of The Cap Free Human Translation Initiation Factor Eif4e
GenPept345111041C Chain C, Crystal Structure Of The Cap Free Human Translation Initiation Factor Eif4e
GenPept345111042D Chain D, Crystal Structure Of The Cap Free Human Translation Initiation Factor Eif4e
GenPept355333196A Chain A, Crystal Structure Of The Human Eif4e-4ebp1 Peptide Complex Without Cap
GenPept355333197B Chain B, Crystal Structure Of The Human Eif4e-4ebp1 Peptide Complex Without Cap
GenPept380784325eukaryotic translation initiation factor 4E isoform 1
GenPept383408599eukaryotic translation initiation factor 4E isoform 1
GenPept4503535 eukaryotic translation initiation factor 4E isoform 1 [Homo sapiens]
GenPept345101024B Chain B, Crystal Structure Of The Human Eif4e-4ebp1 Peptide Complex Without Cap
GenPept345101023A Chain A, Crystal Structure Of The Human Eif4e-4ebp1 Peptide Complex Without Cap
GenPept90078144unnamed protein product
GenPept88163A26411 translation initiation factor eIF-4E - human
GenPept757925659Sequence 1 from patent US 8604692
GenPept62552573unnamed protein product
GenPept61363092eukaryotic translation initiation factor 4E
GenPept5953986Sequence 2 from patent US 5872011
GenPept313716700unnamed protein product
GenPept313742146unnamed protein product
GenPept54673606Eukaryotic translation initiation factor 4E
GenPept343958478eukaryotic translation initiation factor 4E
UCSCGenomeBrowserP06730 
ENSEMBLENSP00000280892 
ENSEMBLENSPTRP00000027997 
ENSEMBLENSP00000280892TDI sequence
ENSEMBLENSP00000389624