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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link P12694.2
Original Database ID EN GENSCAN00000045235
Organism Homo sapiens
Annotation odba_human recname: full=2-oxoisovalerate
dehydrogenase subunit alpha, mitochond
rial; altname: full=branched-chain
alpha-keto acid dehydrogenase
e1 c ...
Sequence Length 445

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region59-445
Protein Length445
Template PDB Code1v1rA
Template Region14-400
Sequence Identity85%
E-Value0
GA3411
MPQS1.75386
z-DOPE-0.4
TSVMod MethodMSALL
TSVMod RMSD2.289
TSVMod NO350.974
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB1v1rcrosstalk between cofactor binding and the phosphorylation loop conformation in the bckd machine
DBALI1v1rA 
CATH3.40.50.970 Domain: 1v1rA00 Rossmann fold (100%)
JenaImageLibrary1v1r 
Target Sequence
UniProtKBQ16472RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial;EC=1.2.4.4;AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain;Short=BCKDE1A;Short=BCKDH E1-al
InterProQ16472 
PFAMQ16472 
ProdomQ16472 
UniProtKBA0A024R0K3SubName: Full=Branched chain keto acid dehydrogenase E1, alpha polypeptide, isoform CRA_a {ECO:0000313|EMBL:EAW57039.1};
InterProA0A024R0K3 
PFAMA0A024R0K3 
ProdomA0A024R0K3 
UniProtKBP12694RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial;EC=1.2.4.4;AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain;Short=BCKDE1A;Short=BCKDH E1-al
InterProP12694 
PFAMP12694 
ProdomP12694 
UniProtKBQ16034RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial;EC=1.2.4.4;AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain;Short=BCKDE1A;Short=BCKDH E1-al
InterProQ16034 
PFAMQ16034 
ProdomQ16034 
UniProtKBQ16034RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial;EC=1.2.4.4;AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain;Short=BCKDE1A;Short=BCKDH E1-al
InterProQ16034 
PFAMQ16034 
ProdomQ16034 
UniProtKBP12694.2ODBA_HUMAN RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain; Short=BCKDE1A; Short=BCKDH E1
InterProP12694.2 
PFAMP12694.2 
ProdomP12694.2 
UniProtKBP12694RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial;EC=1.2.4.4;AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain;Short=BCKDE1A;Short=BCKDH E1-al
InterProP12694 
PFAMP12694 
ProdomP12694 
UniProtKBQ16472RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial;EC=1.2.4.4;AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain;Short=BCKDE1A;Short=BCKDH E1-al
InterProQ16472 
PFAMQ16472 
ProdomQ16472 
UniProtKBE7EW46RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial;EC=1.2.4.4;AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain;Short=BCKDE1A;Short=BCKDH E1-al
InterProE7EW46 
PFAME7EW46 
ProdomE7EW46 
UniProtKBB4DP47RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial;EC=1.2.4.4;AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain;Short=BCKDE1A;Short=BCKDH E1-al
InterProB4DP47 
PFAMB4DP47 
ProdomB4DP47 
RefSeqNP_000700.1 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform 1 precursor [Homo sapiens]
GenPept11386135 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform 1 precursor [Homo sapiens]
GenPept568536344Sequence 28480 from patent US 8586006
GenPept549828340Sequence 71 from patent US 8541550
GenPept548403ODBA_HUMAN RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain; Short=BCKDE1A; Short=BCKDH E1
GenPept18645155Branched chain keto acid dehydrogenase E1, alpha polypeptide
GenPept14786823 branched chain keto acid dehydrogenase E1, alpha polypeptide (maple syrup urine disease) [Homo sapiens]
GenPept14286270Branched chain keto acid dehydrogenase E1, alpha polypeptide
GenPept29391branched chain decarboxylase alpha subunit
GenPept14043871Branched chain keto acid dehydrogenase E1, alpha polypeptide
GenPept353306106Sequence 71 from patent US 8039587
GenPept119577444branched chain keto acid dehydrogenase E1, alpha polypeptide, isoform CRA_a
GenPept119577443branched chain keto acid dehydrogenase E1, alpha polypeptide, isoform CRA_a
GenPept358782499Sequence 71 from patent US 8062891
GenPept516171720Sequence 71 from patent US 8470972
GenPept534490756Sequence 71 from patent US 8507277
GenPept2144336DEHUXA 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.4) alpha chain precursor - human
GenBankEAW57040.1 branched chain keto acid dehydrogenase E1, alpha polypeptide, isoform CRA_a [Homo sapiens]
GenBankEAW57039.1 branched chain keto acid dehydrogenase E1, alpha polypeptide, isoform CRA_a [Homo sapiens]
GenBankAAH23983.1 Branched chain keto acid dehydrogenase E1, alpha polypeptide [Homo sapiens]
GenBankAAH08933.1 Branched chain keto acid dehydrogenase E1, alpha polypeptide [Homo sapiens]
GenBankAAH07878.1 Branched chain keto acid dehydrogenase E1, alpha polypeptide [Homo sapiens]
ENSEMBLENSP000002699802-oxoisovalerate dehydrogenase alpha subunit, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A). [Homo sapiens]
EMBLCAA78475.1 
ENSEMBLENSP00000269980 
ENSEMBLENSP00000269980TDI sequence
ENSEMBLGENSCAN00000025530 
ENSEMBLENSP00000269980 
UCSCGenomeBrowserP12694