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Sequence Information

Primary Database Link A8K3P0
Original Database ID EN ENSP00000233057.4
Organism Homo sapiens, synthetic construct
Annotation subname: full=cdna flj78089, highly
similar to homo sapiens eukaryotic
translati on initiation factor
2-alpha kinase 2 (eif2ak2), mrna;subname:
full=c ...
Sequence Length 551

Dataset Information:

The newest dataset for this sequence was created on 2020-05-15. If you think that a better template has been added to the template database since, you can start a new calculation.

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Model Information

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Target Region125-526
Protein Length551
Template PDB Code3pfqA
Template Region185-583
Sequence Identity24%
E-Value0
GA3411
MPQS0.765383
z-DOPE1.12
TSVMod MethodMSALL
TSVMod RMSD11.146
TSVMod NO350.394
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in advanced pancreatic tumor for CCDS1786.1 R307C
Template Structure
PDB3pfq
DBALI3pfqA 
JenaImageLibrary3pfq 
Target Sequence
UniProtKBQ9UIR4RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProQ9UIR4 
PFAMQ9UIR4 
ProdomQ9UIR4 
UniProtKBE9PC80RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProE9PC80 
PFAME9PC80 
ProdomE9PC80 
UniProtKBD6W584RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProD6W584 
PFAMD6W584 
ProdomD6W584 
UniProtKBP19525RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProP19525 
PFAMP19525 
ProdomP19525 
UniProtKBA8K3P0RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProA8K3P0 
PFAMA8K3P0 
ProdomA8K3P0 
UniProtKBQ52M43RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProQ52M43 
PFAMQ52M43 
ProdomQ52M43 
UniProtKBQ7Z6F6RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProQ7Z6F6 
PFAMQ7Z6F6 
ProdomQ7Z6F6 
UniProtKBQ52M43Eukaryotic translation initiation factor 2-alpha kinase 2DE (Hypothetical protein PRKR)
InterProQ52M43 
PFAMQ52M43 
ProdomQ52M43 
UniProtKBD6W584SubName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2, isoform CRA_a;
InterProD6W584 
PFAMD6W584 
ProdomD6W584 
UniProtKBA8K3P0SubName: Full=cDNA FLJ78089, highly similar to Homo sapiens eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), mRNA;SubName: Full=cDNA, FLJ94439, Homo sapiens protein kinase, interfe
InterProA8K3P0 
PFAMA8K3P0 
ProdomA8K3P0 
UniProtKBA8K3P0RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProA8K3P0 
PFAMA8K3P0 
ProdomA8K3P0 
UniProtKBD6W584RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProD6W584 
PFAMD6W584 
ProdomD6W584 
UniProtKBQ9UIR4RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProQ9UIR4 
PFAMQ9UIR4 
ProdomQ9UIR4 
UniProtKBE9PC80RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProE9PC80 
PFAME9PC80 
ProdomE9PC80 
UniProtKBQ7Z6F6RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProQ7Z6F6 
PFAMQ7Z6F6 
ProdomQ7Z6F6 
UniProtKBP19525RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProP19525 
PFAMP19525 
ProdomP19525 
UniProtKBQ52M43RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;EC=2.7.11.1;AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;Short=eIF-2A protein kinase 2;AltName
InterProQ52M43 
PFAMQ52M43 
ProdomQ52M43 
UniProtKBP19525.2E2AK2_HUMAN RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase; AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2; Short=eIF-2A protein kinase 2; AltN
InterProP19525.2 
PFAMP19525.2 
ProdomP19525.2 
RefSeqNP_001129123.1 interferon-induced, double-stranded RNA-activated protein kinase isoform a [Homo sapiens]
RefSeqNP_002750.1 interferon-induced, double-stranded RNA-activated protein kinase isoform a [Homo sapiens]
GenPept189506p68 kinase
GenPept756950707Sequence 469 from patent US 8865653
GenPept756818679Sequence 469 from patent US 8828944
GenPept756521752Sequence 150 from patent US 8741556
GenPept75517635Eukaryotic translation initiation factor 2-alpha kinase 2
GenPept649102479EIF2AK2, partial
GenPept62988930unknown
GenPept62739920Eukaryotic translation initiation factor 2-alpha kinase 2
GenPept61354795protein kinase interferon-inducible double stranded RNA dependent
GenPept314281937Sequence 1 from patent US 7776527
GenPept284897730Sequence 906 from patent US 7638288
GenPept28372413protein kinase, interferon-inducible double stranded RNA dependent
GenPept223088252Sequence 6268 from patent US 6812339
GenPept2136014JC5225 dsRNA-activated protein kinase (EC 2.7.1.-) - human
GenPept208431827 interferon-induced, double-stranded RNA-activated protein kinase isoform a [Homo sapiens]
GenPept189782P1/eIF-2a protein kinase
GenPept189054047unnamed protein product
GenPept158254742unnamed protein product
GenPept1537049interferon-inducible RNA-dependent protein kinase
GenPept125527E2AK2_HUMAN RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase; AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2; Short=eIF-2A protein kinase 2; AltN
GenPept119620814eukaryotic translation initiation factor 2-alpha kinase 2, isoform CRA_a
GenPept119620813eukaryotic translation initiation factor 2-alpha kinase 2, isoform CRA_a
GenPept119620812eukaryotic translation initiation factor 2-alpha kinase 2, isoform CRA_a
GenPept119620811eukaryotic translation initiation factor 2-alpha kinase 2, isoform CRA_a
GenPept339827690Sequence 74 from patent US 7977052
GenPept339827691Sequence 75 from patent US 7977052
GenPept443746115Sequence 906 from patent US 8338124
GenPept5947870Sequence 9 from patent US 5866787
GenPept5947856Sequence 9 from patent US 5866781
GenPept5944578Sequence 9 from patent US 5861300
GenPept4506103 interferon-induced, double-stranded RNA-activated protein kinase isoform a [Homo sapiens]
GenPept339827692Sequence 76 from patent US 7977052
GenPept397030820Sequence 391 from patent US 8216786
GenPept339827693Sequence 77 from patent US 7977052
GenBankAAY24317.1 unknown [Homo sapiens]
GenBankAAA18253.1 P1/eIF-2a protein kinase [Homo sapiens]
GenBankAAA36409.1 p68 kinase [Homo sapiens]
GenBankAAC50768.1 interferon-inducible RNA-dependent protein kinase [Homo sapiens]
GenBankAAX41060.1 protein kinase interferon-inducible double stranded RNA dependent [synthetic construct]
GenBankAAO38055.1 protein kinase, interferon-inducible double stranded RNA dependent [Homo sapiens]
GenBankAAI01476.1 Eukaryotic translation initiation factor 2-alpha kinase 2 [Homo sapiens]
GenBankAAH93676.1 Eukaryotic translation initiation factor 2-alpha kinase 2 [Homo sapiens]
GenBankEAX00407.1 eukaryotic translation initiation factor 2-alpha kinase 2, isoform CRA_a [Homo sapiens]
GenBankEAX00408.1 eukaryotic translation initiation factor 2-alpha kinase 2, isoform CRA_a [Homo sapiens]
GenBankEAX00409.1 eukaryotic translation initiation factor 2-alpha kinase 2, isoform CRA_a [Homo sapiens]
GenBankEAX00406.1 eukaryotic translation initiation factor 2-alpha kinase 2, isoform CRA_a [Homo sapiens]
ENSEMBLENSP00000233057Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.1.-) (Interferon-inducible RNA-dependent protein kinase) (p68 kinase) (P1/eIF-2A protein kinase). [Homo sapiens]
UCSCGenomeBrowserP19525 
ENSEMBLENSP00000233057 
ENSEMBLENSP00000233057TDI sequence
ENSEMBLENSP00000233057