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ModBase: Database of Comparative Protein Structure Models

Model Details Page

Sequence Information

Primary Database Link B2R9Q3
Original Database ID EN ENSP00000295266.4
Organism Homo sapiens
Annotation subname: full=cdna, flj94505,
homo sapiens pyruvate dehydrogenase
(lipoamide) al pha 2 (pdha2),
mrna;
Sequence Length 388

Dataset Information:

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Model Information

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Target Region24-388
Protein Length388
Template PDB Code3exiA
Template Region-3-361
Sequence Identity85%
E-Value0
GA3411
MPQS1.79302
z-DOPE-0.45
TSVMod MethodMTALL
TSVMod RMSD8.825
TSVMod NO350.856
DatasetMW-Human_D15
ModPipe VersionSVN.r1693
Model Date2020-05-15

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Cross-references

Show obsolete/secondary identifiers
Mutation Data
LS-Mut Somatic mutation found in glioblastoma multiforme for CCDS3644.1 E307K
LS-SNP SNP Information available through LS-SNP
Template Structure
PDB3exicrystal structure of the pyruvate dehydrogenase (e1p) component of human pyruvate dehydrogenase complex with the subunit-binding domain (sbd) of e2p, but sbd cannot be modeled into the electron densit
DBALI3exiA 
JenaImageLibrary3exi 
Target Sequence
UniProtKBQ4VC02RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProQ4VC02 
PFAMQ4VC02 
ProdomQ4VC02 
UniProtKBQ0VDI5RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProQ0VDI5 
PFAMQ0VDI5 
ProdomQ0VDI5 
UniProtKBB2R9Q3RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProB2R9Q3 
PFAMB2R9Q3 
ProdomB2R9Q3 
UniProtKBQ6NXQ1RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProQ6NXQ1 
PFAMQ6NXQ1 
ProdomQ6NXQ1 
UniProtKBP29803RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProP29803 
PFAMP29803 
ProdomP29803 
UniProtKBB2R9Q3SubName: Full=cDNA, FLJ94505, Homo sapiens pyruvate dehydrogenase (lipoamide) alpha 2 (PDHA2), mRNA;
InterProB2R9Q3 
PFAMB2R9Q3 
ProdomB2R9Q3 
UniProtKBQ6NXQ1RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProQ6NXQ1 
PFAMQ6NXQ1 
ProdomQ6NXQ1 
UniProtKBB2R9Q3RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProB2R9Q3 
PFAMB2R9Q3 
ProdomB2R9Q3 
UniProtKBP29803RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProP29803 
PFAMP29803 
ProdomP29803 
UniProtKBP29803.1ODPAT_HUMAN RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; AltName: Full=PDHE1-A type II; Flags: Precursor
InterProP29803.1 
PFAMP29803.1 
ProdomP29803.1 
UniProtKBQ0VDI5RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProQ0VDI5 
PFAMQ0VDI5 
ProdomQ0VDI5 
UniProtKBQ4VC02RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;EC=1.2.4.1;AltName: Full=PDHE1-A type II;Flags: Precursor;
InterProQ4VC02 
PFAMQ4VC02 
ProdomQ4VC02 
RefSeqNP_005381.1 pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial precursor [Homo sapiens]
GenPept133777220Pyruvate dehydrogenase (lipoamide) alpha 2
GenPept66038DEHUPT pyruvate dehydrogenase (lipoamide) (EC 1.2.4.1) alpha chain precursor, testis-specific - human
GenPept649152818PDHA2, partial
GenPept568560763Sequence 63344 from patent US 8586006
GenPept549828339Sequence 70 from patent US 8541550
GenPept534490755Sequence 70 from patent US 8507277
GenPept261385786unnamed protein product
GenPept21265170pyruvate dehydrogenase (lipoamide
GenPept190790pyruvate dehydrogenase complex
GenPept189066860unnamed protein product
GenPept121934212Pyruvate dehydrogenase (lipoamide) alpha 2
GenPept121934094Pyruvate dehydrogenase (lipoamide) alpha 2
GenPept11435278 pyruvate dehydrogenase (lipoamide) alpha 2 [Homo sapiens]
GenPept111185648Pyruvate dehydrogenase (lipoamide) alpha 2
GenPept111185646Pyruvate dehydrogenase (lipoamide) alpha 2
GenPept262270985unnamed protein product
GenPept266687ODPAT_HUMAN RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial; AltName: Full=PDHE1-A type II; Flags: Precursor
GenPept353306105Sequence 70 from patent US 8039587
GenPept358782498Sequence 70 from patent US 8062891
GenPept516171718Sequence 70 from patent US 8470972
GenPept4885543 pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial precursor [Homo sapiens]
GenBankAAA60232.1 pyruvate dehydrogenase complex [Homo sapiens]
GenBankAAH30697.3 Pyruvate dehydrogenase (lipoamide) alpha 2 [Homo sapiens]
GenBankAAI19657.1 Pyruvate dehydrogenase (lipoamide) alpha 2 [Homo sapiens]
GenBankAAI19658.1 Pyruvate dehydrogenase (lipoamide) alpha 2 [Homo sapiens]
GenBankAAI27638.1 Pyruvate dehydrogenase (lipoamide) alpha 2 [Homo sapiens]
GenBankAAI27639.1 Pyruvate dehydrogenase (lipoamide) alpha 2 [Homo sapiens]
ENSEMBLENSP00000295266Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial precursor (EC 1.2.4.1) (PDHE1-A type II). [Homo sapiens]
ENSEMBLENSP00000295266 
ENSEMBLENSP00000295266TDI sequence
ENSEMBLENSP00000295266 
UCSCGenomeBrowserP29803